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The map label for this gene is cat2 [H]

Identifier: 134299348

GI number: 134299348

Start: 1611494

End: 1612837

Strand: Reverse

Name: cat2 [H]

Synonym: Dred_1489

Alternate gene names: 134299348

Gene position: 1612837-1611494 (Counterclockwise)

Preceding gene: 134299349

Following gene: 134299346

Centisome position: 44.7

GC content: 42.19

Gene sequence:

>1344_bases
GTGGCAAATTTTTCTGATTTGTATAAGAGTAAGTTAACAACGCCCGACCAAGCAGTCAGCGTTGTTAAATCCGGGGATTG
GGTGGATTACAATTCCTTTACAGGCCGCCCCATAGTGTTAGACAGAGCTTTGGCCAAAAGAAAAGATGAATTAAGCGATG
TTAAAGTACGATCAACATGCACCATGTATGGGGTTCCAGAGATTGTAAAGGTTGATCCTACATCTCAACATTTCGTTTAC
AACAACTGGCACTTCGGCGGCCTTGACCGTAAATTAGCCGATCAGGGAAGCTGTTGGTACGCACCAGTACTTTATCGTGA
AGTTATTAAATATTATGAAAAACATGTAGATGTGGATGTTGCTTTCTTACAAGTCTGCCCGATGGATAAAAATGGCCTCT
TCAACTTGGGTATACAAGCTTCCCATGCCAGAGCCATCATTAACAAGGCTAAAATAGTCATTCTTGAGGTAAACCAAAAT
ATGCCCCGGGCATTGGGTGGCTATAATGAAGTAGTTCATATTTCAGAAGTTGACTATGTGGTTGAAGGGGATAACCCACC
TTTGCCACAAATTCCTGCAGCCGTTCCAACGGATGCTGATCGAAAAATTGCCCAATATGTTTTAGAGGAAATTGAAGATG
GTTCTTGTATCCAGTTGGGTATTGGCGCTATGCCCAACGTGGTAGGAAAATTGTTAGCCGAATCGGATTTAAAAGACCTG
GGCGCCCACACCGAAATGTTAGTGGATGCCTATGTGGATATGTATGAATCCGGCGTATTAACAGGTCGCAAGAAGAAAAT
TGACCAACATAAAATCGTTTATACCTTTGCTATGGGTACACAAAGATTATATGATTTTATTGACGACAACCCTATATGTG
CCATCTACCCAGTAAATTATACTAATAATACTCGAATCATTGCCCAAAATGACAAGGTGATGTCTATTAACAACGCTGTG
GAGATAGACTTATTTGGTCAGGTAAATTCTGAGACCTCAGGCATACGGCAAATCAGTGGTACAGGTGGTCAACTTGACTT
TATAACCGGTGCTTATGAATCCCAGGGCGGCAAGAGTTTTATTTGTCTCACCTCAAACTATAAAGATAAAAGTGGCAAGG
CTATTTCACGGATCAGACCTTTCCTAGGAAATGGCACTGTAGTAACAGCCCCCAGAACATCGGTTGAATATGTCATTACC
GAATACGGTAAGGCTATTATGAAAGCCAAGTCTACCTGGGAACGGGCAGAAGCCCTTATTGGCATTGCCCATCCTGATTC
TCGGGAGGAATTAATCAAAGCGGCGGAAGATATGGGTATCTGGCGAAGAAGCAATAAACTATAA

Upstream 100 bases:

>100_bases
AAAATCATGCAAATTTATGAAGGCACCAGTCAAGTTCAACGGGTTGTTATTGCCGGCAATATGTTGAAATAGTTCTGTCT
AATGAAAGGAGGAAAACCGG

Downstream 100 bases:

>100_bases
AAAACACTATACAATAAAAAATCCCGTATCACTTAGCTAGTGACACGGGATTTTTTATGGTTCTCTTTGTTTTATCCAGT
TCATTTACTTCTTAAGGAAT

Product: acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MANFSDLYKSKLTTPDQAVSVVKSGDWVDYNSFTGRPIVLDRALAKRKDELSDVKVRSTCTMYGVPEIVKVDPTSQHFVY
NNWHFGGLDRKLADQGSCWYAPVLYREVIKYYEKHVDVDVAFLQVCPMDKNGLFNLGIQASHARAIINKAKIVILEVNQN
MPRALGGYNEVVHISEVDYVVEGDNPPLPQIPAAVPTDADRKIAQYVLEEIEDGSCIQLGIGAMPNVVGKLLAESDLKDL
GAHTEMLVDAYVDMYESGVLTGRKKKIDQHKIVYTFAMGTQRLYDFIDDNPICAIYPVNYTNNTRIIAQNDKVMSINNAV
EIDLFGQVNSETSGIRQISGTGGQLDFITGAYESQGGKSFICLTSNYKDKSGKAISRIRPFLGNGTVVTAPRTSVEYVIT
EYGKAIMKAKSTWERAEALIGIAHPDSREELIKAAEDMGIWRRSNKL

Sequences:

>Translated_447_residues
MANFSDLYKSKLTTPDQAVSVVKSGDWVDYNSFTGRPIVLDRALAKRKDELSDVKVRSTCTMYGVPEIVKVDPTSQHFVY
NNWHFGGLDRKLADQGSCWYAPVLYREVIKYYEKHVDVDVAFLQVCPMDKNGLFNLGIQASHARAIINKAKIVILEVNQN
MPRALGGYNEVVHISEVDYVVEGDNPPLPQIPAAVPTDADRKIAQYVLEEIEDGSCIQLGIGAMPNVVGKLLAESDLKDL
GAHTEMLVDAYVDMYESGVLTGRKKKIDQHKIVYTFAMGTQRLYDFIDDNPICAIYPVNYTNNTRIIAQNDKVMSINNAV
EIDLFGQVNSETSGIRQISGTGGQLDFITGAYESQGGKSFICLTSNYKDKSGKAISRIRPFLGNGTVVTAPRTSVEYVIT
EYGKAIMKAKSTWERAEALIGIAHPDSREELIKAAEDMGIWRRSNKL
>Mature_446_residues
ANFSDLYKSKLTTPDQAVSVVKSGDWVDYNSFTGRPIVLDRALAKRKDELSDVKVRSTCTMYGVPEIVKVDPTSQHFVYN
NWHFGGLDRKLADQGSCWYAPVLYREVIKYYEKHVDVDVAFLQVCPMDKNGLFNLGIQASHARAIINKAKIVILEVNQNM
PRALGGYNEVVHISEVDYVVEGDNPPLPQIPAAVPTDADRKIAQYVLEEIEDGSCIQLGIGAMPNVVGKLLAESDLKDLG
AHTEMLVDAYVDMYESGVLTGRKKKIDQHKIVYTFAMGTQRLYDFIDDNPICAIYPVNYTNNTRIIAQNDKVMSINNAVE
IDLFGQVNSETSGIRQISGTGGQLDFITGAYESQGGKSFICLTSNYKDKSGKAISRIRPFLGNGTVVTAPRTSVEYVITE
YGKAIMKAKSTWERAEALIGIAHPDSREELIKAAEDMGIWRRSNKL

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI32563853, Length=440, Percent_Identity=35.4545454545455, Blast_Score=235, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17538151, Length=440, Percent_Identity=34.3181818181818, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI21358615, Length=428, Percent_Identity=34.8130841121495, Blast_Score=244, Evalue=6e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 49670; Mature: 49539

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANFSDLYKSKLTTPDQAVSVVKSGDWVDYNSFTGRPIVLDRALAKRKDELSDVKVRSTC
CCCHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCCCEEEHHHHHHHHHHHHCEEEEEEE
TMYGVPEIVKVDPTSQHFVYNNWHFGGLDRKLADQGSCWYAPVLYREVIKYYEKHVDVDV
EECCCCCEEEECCCCCCEEEECEEECCCCHHHHCCCCEEEHHHHHHHHHHHHHHHCCCEE
AFLQVCPMDKNGLFNLGIQASHARAIINKAKIVILEVNQNMPRALGGYNEVVHISEVDYV
EEEEECCCCCCCCEEECEECHHHHHHHCCCEEEEEEECCCCCHHHCCCCCEEEEEEEEEE
VEGDNPPLPQIPAAVPTDADRKIAQYVLEEIEDGSCIQLGIGAMPNVVGKLLAESDLKDL
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHH
GAHTEMLVDAYVDMYESGVLTGRKKKIDQHKIVYTFAMGTQRLYDFIDDNPICAIYPVNY
CHHHHHHHHHHHHHHHCCCCCCCHHCCCCEEEEEEEECCHHHHHHHHCCCCEEEEEEECC
TNNTRIIAQNDKVMSINNAVEIDLFGQVNSETSGIRQISGTGGQLDFITGAYESQGGKSF
CCCEEEEEECCCEEEECCEEEEEEEECCCCCCCCCEEECCCCCEEEEEECCCCCCCCCEE
ICLTSNYKDKSGKAISRIRPFLGNGTVVTAPRTSVEYVITEYGKAIMKAKSTWERAEALI
EEEECCCCCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
GIAHPDSREELIKAAEDMGIWRRSNKL
EECCCCCHHHHHHHHHHHCHHHCCCCC
>Mature Secondary Structure 
ANFSDLYKSKLTTPDQAVSVVKSGDWVDYNSFTGRPIVLDRALAKRKDELSDVKVRSTC
CCHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCCCEEEHHHHHHHHHHHHCEEEEEEE
TMYGVPEIVKVDPTSQHFVYNNWHFGGLDRKLADQGSCWYAPVLYREVIKYYEKHVDVDV
EECCCCCEEEECCCCCCEEEECEEECCCCHHHHCCCCEEEHHHHHHHHHHHHHHHCCCEE
AFLQVCPMDKNGLFNLGIQASHARAIINKAKIVILEVNQNMPRALGGYNEVVHISEVDYV
EEEEECCCCCCCCEEECEECHHHHHHHCCCEEEEEEECCCCCHHHCCCCCEEEEEEEEEE
VEGDNPPLPQIPAAVPTDADRKIAQYVLEEIEDGSCIQLGIGAMPNVVGKLLAESDLKDL
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHH
GAHTEMLVDAYVDMYESGVLTGRKKKIDQHKIVYTFAMGTQRLYDFIDDNPICAIYPVNY
CHHHHHHHHHHHHHHHCCCCCCCHHCCCCEEEEEEEECCHHHHHHHHCCCCEEEEEEECC
TNNTRIIAQNDKVMSINNAVEIDLFGQVNSETSGIRQISGTGGQLDFITGAYESQGGKSF
CCCEEEEEECCCEEEECCEEEEEEEECCCCCCCCCEEECCCCCEEEEEECCCCCCCCCEE
ICLTSNYKDKSGKAISRIRPFLGNGTVVTAPRTSVEYVITEYGKAIMKAKSTWERAEALI
EEEECCCCCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
GIAHPDSREELIKAAEDMGIWRRSNKL
EECCCCCHHHHHHHHHHHCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]