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The map label for this gene is ltaA [H]

Identifier: 134298512

GI number: 134298512

Start: 694116

End: 695309

Strand: Reverse

Name: ltaA [H]

Synonym: Dred_0644

Alternate gene names: 134298512

Gene position: 695309-694116 (Counterclockwise)

Preceding gene: 134298513

Following gene: 134298511

Centisome position: 19.27

GC content: 42.46

Gene sequence:

>1194_bases
TTGCTTAACATAATGAATTTAAAGCCACAGGATTATGCTTTTGTTTTATTGCTTTTTATTACAGAATTAACCAGAAGTGC
TTTTTTTCTTACCTTTTGGCCACTGTATTCAGCAGAAGCTTTGCATTTTTCTTTATTTAGTGCTGGTTTGGTGGTTTCTG
CCCACTATTTAATAGAAACGCTTCTTAAATCCTTTGCAGGTTCTCTATTGGATCGTCGTGGACGACCTGTATTGTTACTG
GGTTTGTTAATCAGCTTCATTTCCTTAATTGGCTTATACCATGTTAGATCCCAATGGTTAGCCCTATTATTATCTGGTAC
TTTTGGCCTGGGTTTTACTCCGGTATGGCTGGCTGTTATCAGCAATGTTGCTCCAACTGGTTGCTCCAATCGGGCTGCCA
GAATGGGGTTCGTTTTTTCTGCCTGGCTGCTGGGGATGGGCATCGGCCCTGTTGGAGTTAATTTTGTTCTGGCCAGAGGT
TATCAAAACACATTTAAAATATTTATTTTCTTATGGGCCCTCGGCCTTGTCATTGCTTTACTGGCTCCCTTTGCGGCCAA
AACAACCGCCATCAACTTTACCATTCTAGATCAGGTTAAAAGGTTGGCCTCCGACCGTATGGTGGTTCAAATTTTATTGC
CGGGTATGTTTTTACAGACCCTGGCTGCCAGTTTGTTATTGCCCATATTGCCACTCTACGCAACCCATGTTTTAGATTTG
AGCACCCAACAGTACGGTTTGCTATTAACCATTGGTGGTGCAACTGCGATTCTTTTTCTGGTTCCTATGGGTAGAATGGT
TGATCGTTTTTCTGTAAGAAATCTCTTGTCCCTAGGTTTTTTGTTAAGCGCTCTGTTATTGGGTCTTTTTCCCCTTATTA
GGAATTTGAAACTGATTGTATTCTTGGTATTTCTCGTAGGATTTTCCTATGCCATTATACTGCCAGCCTGGAACTCTCTA
TTGGCCAAGGCCATCCCAGAAGAGCAACAGGCTACGGGTTGGGGTATTTTTACGACCTTGGAAGGTCTGGGCATCGCCGC
TGGTCCCACTCTGGGCGGAGCCATTGCCACTTCCCTCCACCCCGCAGGGGCTATCTATATGAGTGCTTTTATATTAGCCT
TCATGGGTATCTTTTATGTTTTATACCCTGTTGAAGAATTATTAAAAAACCAGGAGAAAGAAAATGTATCTTAA

Upstream 100 bases:

>100_bases
GGCGTTAAGGGAATTGATTGGACATAACCCCTCTGAGGTAGTAGCAGGCGCTTTGCTCGGGGTTGTTATGGCCTCGGTGG
TTTTTTAAGGAGATTGCATA

Downstream 100 bases:

>100_bases
CGTTTTTAAGCTCGCTGGCATAGCATTCTTTATTTACATACTGTTACCAACATTCCTGGGCAGGGTCCTTTCCATTGGAT
CCTATCGTAGGGGAAACAAA

Product: major facilitator transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: Lipoteichoic acid protein A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MLNIMNLKPQDYAFVLLLFITELTRSAFFLTFWPLYSAEALHFSLFSAGLVVSAHYLIETLLKSFAGSLLDRRGRPVLLL
GLLISFISLIGLYHVRSQWLALLLSGTFGLGFTPVWLAVISNVAPTGCSNRAARMGFVFSAWLLGMGIGPVGVNFVLARG
YQNTFKIFIFLWALGLVIALLAPFAAKTTAINFTILDQVKRLASDRMVVQILLPGMFLQTLAASLLLPILPLYATHVLDL
STQQYGLLLTIGGATAILFLVPMGRMVDRFSVRNLLSLGFLLSALLLGLFPLIRNLKLIVFLVFLVGFSYAIILPAWNSL
LAKAIPEEQQATGWGIFTTLEGLGIAAGPTLGGAIATSLHPAGAIYMSAFILAFMGIFYVLYPVEELLKNQEKENVS

Sequences:

>Translated_397_residues
MLNIMNLKPQDYAFVLLLFITELTRSAFFLTFWPLYSAEALHFSLFSAGLVVSAHYLIETLLKSFAGSLLDRRGRPVLLL
GLLISFISLIGLYHVRSQWLALLLSGTFGLGFTPVWLAVISNVAPTGCSNRAARMGFVFSAWLLGMGIGPVGVNFVLARG
YQNTFKIFIFLWALGLVIALLAPFAAKTTAINFTILDQVKRLASDRMVVQILLPGMFLQTLAASLLLPILPLYATHVLDL
STQQYGLLLTIGGATAILFLVPMGRMVDRFSVRNLLSLGFLLSALLLGLFPLIRNLKLIVFLVFLVGFSYAIILPAWNSL
LAKAIPEEQQATGWGIFTTLEGLGIAAGPTLGGAIATSLHPAGAIYMSAFILAFMGIFYVLYPVEELLKNQEKENVS
>Mature_397_residues
MLNIMNLKPQDYAFVLLLFITELTRSAFFLTFWPLYSAEALHFSLFSAGLVVSAHYLIETLLKSFAGSLLDRRGRPVLLL
GLLISFISLIGLYHVRSQWLALLLSGTFGLGFTPVWLAVISNVAPTGCSNRAARMGFVFSAWLLGMGIGPVGVNFVLARG
YQNTFKIFIFLWALGLVIALLAPFAAKTTAINFTILDQVKRLASDRMVVQILLPGMFLQTLAASLLLPILPLYATHVLDL
STQQYGLLLTIGGATAILFLVPMGRMVDRFSVRNLLSLGFLLSALLLGLFPLIRNLKLIVFLVFLVGFSYAIILPAWNSL
LAKAIPEEQQATGWGIFTTLEGLGIAAGPTLGGAIATSLHPAGAIYMSAFILAFMGIFYVLYPVEELLKNQEKENVS

Specific function: Probable permease that is required for glycolipid anchoring of LTA. May facilitate the transport of diglucosyl- diacylglycerol (Glc2-DAG) from the inner to the outer leaflet of the cytoplasmic membrane, delivering Glc2-DAG as a substrate for LTA synthesis

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. LtaA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43357; Mature: 43357

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNIMNLKPQDYAFVLLLFITELTRSAFFLTFWPLYSAEALHFSLFSAGLVVSAHYLIET
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLKSFAGSLLDRRGRPVLLLGLLISFISLIGLYHVRSQWLALLLSGTFGLGFTPVWLAVI
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SNVAPTGCSNRAARMGFVFSAWLLGMGIGPVGVNFVLARGYQNTFKIFIFLWALGLVIAL
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHEECCCHHHHHHHHHHHHHHHHHHH
LAPFAAKTTAINFTILDQVKRLASDRMVVQILLPGMFLQTLAASLLLPILPLYATHVLDL
HHCHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
STQQYGLLLTIGGATAILFLVPMGRMVDRFSVRNLLSLGFLLSALLLGLFPLIRNLKLIV
CCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLVFLVGFSYAIILPAWNSLLAKAIPEEQQATGWGIFTTLEGLGIAAGPTLGGAIATSLH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHCC
PAGAIYMSAFILAFMGIFYVLYPVEELLKNQEKENVS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLNIMNLKPQDYAFVLLLFITELTRSAFFLTFWPLYSAEALHFSLFSAGLVVSAHYLIET
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLKSFAGSLLDRRGRPVLLLGLLISFISLIGLYHVRSQWLALLLSGTFGLGFTPVWLAVI
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SNVAPTGCSNRAARMGFVFSAWLLGMGIGPVGVNFVLARGYQNTFKIFIFLWALGLVIAL
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHEECCCHHHHHHHHHHHHHHHHHHH
LAPFAAKTTAINFTILDQVKRLASDRMVVQILLPGMFLQTLAASLLLPILPLYATHVLDL
HHCHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
STQQYGLLLTIGGATAILFLVPMGRMVDRFSVRNLLSLGFLLSALLLGLFPLIRNLKLIV
CCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLVFLVGFSYAIILPAWNSLLAKAIPEEQQATGWGIFTTLEGLGIAAGPTLGGAIATSLH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHCC
PAGAIYMSAFILAFMGIFYVLYPVEELLKNQEKENVS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA