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The map label for this gene is ubiB [C]

Identifier: 126697242

GI number: 126697242

Start: 1638172

End: 1640028

Strand: Direct

Name: ubiB [C]

Synonym: P9301_19041

Alternate gene names: 126697242

Gene position: 1638172-1640028 (Clockwise)

Preceding gene: 126697238

Following gene: 126697243

Centisome position: 99.77

GC content: 31.83

Gene sequence:

>1857_bases
ATGAAAGAAGATTTTACTGATTTTATTGAGGTATCTGGACTCTTAAATTACGATCCGGATACAATTTCTAAAATTTACAA
AAAAAATCCTAAAAGACTTTTAAAAAGACTTTGGCAAACACTCATACCTATTTTTGCTTACATTTTCTCCGTGGGATGGG
ATAAATTCACTGGAAGATTAAAAAATGAACAGCAAGCAAGATTTAGAGCACGAGAATTAACAAATTTATTAGTAGAACTT
GGGCCTGCATTTGTTAAGGCAGGCCAAGCTTTATCAACAAGACCAGATATAATCCCAGGGATTCTTCTAGAAGAATTATC
TGAATTGCAAGATCAACTCCCCGGGTTTGATGGCAATAAAGCTATGGAGTTAATAGAAGAAGATTTAGGATACAAAATAA
ATGAGATTTTTTTAGAAATTGATAAAGAACCAATTTCCGCTGCTTCTTTAGGGCAAGTACATAAAGCGAAATTAAAAAAC
GAAGAGATCGTTGCAATAAAAGTTCAAAGGCCAGGATTGAGAGAACAAATAACCTTAGATCTCTATATAGTTAGAAATAT
TGCTTATTGGCTAAAAAACAATATCGGATTAATAAGAAGTGATCTAGTTGCTTTGATTGATGAATTAGGCAAAAGAGTTT
TTGAGGAGATGGATTATCTAAACGAAGCTGCAAATGCAGAAAAATTTAGAGATATGCACAAACATAACAAAATGATTGCT
GTACCAAAAATTTATAAAGAAATAACATCAAGAAGAGTATTAGCAATGGAATGGATAGACGGTACAAAATTAACAAATTT
AGAAGACGTAAAAAAATTAGGAATTAATCCTGATGAAATGATTGATATAGGAGTGCAATGCAGTTTAGAACAGCTTTTAG
AACATGGTTTTTTTCATGCAGACCCACATCCAGGTAATTTATTAGCCTTAGAAGATGGAAGATTATGTTACTTAGATTTT
GGAATGATGAGCGAGGTTTCTAGAGAATCAAGATCGGGATTAATTCAAGCAGTAGTACATTTAGTAAATAAAAACTTCGA
TAAATTGTCTCAAGATTTCGTAAAATTGGGATTTTTATCAGAGGAAGTTAATCTAGAGCCCATTGTTCCAGCATTTCAAG
ATGTTTTCATTAACGCCGTTGAACAAGGAGTGTCGAAAATGGATTTTAAAAGCGTTACAGACGATATGTCTGGTGTTATG
TATAAATTCCCTTTCAGACTACCACCATATTACGCGCTTATAATTAGGTCATTACTTACATTAGAAGGAATAGCTTTAAG
CGTAGATCCAAACTTCAAGATATTAGGCGCGGCTTATCCATATTTTGCAAGAAGATTGATGGAAGATCCTGATCCACAAT
TAAGGGAAAGTCTTAAAGAAATGCTTTTTGATAATAAAAAATTTAAATGGGACCGTTTAGAAGATCTACTTTCTAACGCT
GCAAAGCAAACAAATCTCGATTTAGAAAAACTTTTAGACGAAGTTATAAATCTTCTCTTTTCTCCAAATGGAGGATTTCT
TAGAAATGAGATAGTTGAAGGTTTAACAAATCAGATAGATTTATTTAGTCTAAAAATATTGAAAAGTTTGAATAACTACC
TTCCACAATCAATTAAATTAAATACTATCAACGAGAATAATAACTTAAATGACCTTATAATGTACGTAGAGCCATTGAGA
AACTTCTTAGAGATTTTACAAAAAGTCCCCGGGTATTCAATTGATATTTTTCTAAAAAGGGTTCCAAGACTAATAAATGA
ACCTTATACAAAAGAAATGGGTATAAAGATTGCAAAAAAAGTAACTGAAAAAGGAGTAGTAAGACTTGTTAAGATTGCTG
CTGGTGCAAATATCTAA

Upstream 100 bases:

>100_bases
GCAATATTTTCTATTTTTAGTTGTACTAACATGATAAATCTTCCATATAAAAAAATTAACTTCTTTTTTAAAAAAATAAA
GGTTTTAAATATATAAAGTT

Downstream 100 bases:

>100_bases
ATGAAGTTTAGCAAAATTTTAATATTTAAAATATTTTTTATTTTAGTAATTTCTCCATTATTTTTAAATATTCCAAAAGC
TAATAGTGCTGAAGAAATTA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MKEDFTDFIEVSGLLNYDPDTISKIYKKNPKRLLKRLWQTLIPIFAYIFSVGWDKFTGRLKNEQQARFRARELTNLLVEL
GPAFVKAGQALSTRPDIIPGILLEELSELQDQLPGFDGNKAMELIEEDLGYKINEIFLEIDKEPISAASLGQVHKAKLKN
EEIVAIKVQRPGLREQITLDLYIVRNIAYWLKNNIGLIRSDLVALIDELGKRVFEEMDYLNEAANAEKFRDMHKHNKMIA
VPKIYKEITSRRVLAMEWIDGTKLTNLEDVKKLGINPDEMIDIGVQCSLEQLLEHGFFHADPHPGNLLALEDGRLCYLDF
GMMSEVSRESRSGLIQAVVHLVNKNFDKLSQDFVKLGFLSEEVNLEPIVPAFQDVFINAVEQGVSKMDFKSVTDDMSGVM
YKFPFRLPPYYALIIRSLLTLEGIALSVDPNFKILGAAYPYFARRLMEDPDPQLRESLKEMLFDNKKFKWDRLEDLLSNA
AKQTNLDLEKLLDEVINLLFSPNGGFLRNEIVEGLTNQIDLFSLKILKSLNNYLPQSIKLNTINENNNLNDLIMYVEPLR
NFLEILQKVPGYSIDIFLKRVPRLINEPYTKEMGIKIAKKVTEKGVVRLVKIAAGANI

Sequences:

>Translated_618_residues
MKEDFTDFIEVSGLLNYDPDTISKIYKKNPKRLLKRLWQTLIPIFAYIFSVGWDKFTGRLKNEQQARFRARELTNLLVEL
GPAFVKAGQALSTRPDIIPGILLEELSELQDQLPGFDGNKAMELIEEDLGYKINEIFLEIDKEPISAASLGQVHKAKLKN
EEIVAIKVQRPGLREQITLDLYIVRNIAYWLKNNIGLIRSDLVALIDELGKRVFEEMDYLNEAANAEKFRDMHKHNKMIA
VPKIYKEITSRRVLAMEWIDGTKLTNLEDVKKLGINPDEMIDIGVQCSLEQLLEHGFFHADPHPGNLLALEDGRLCYLDF
GMMSEVSRESRSGLIQAVVHLVNKNFDKLSQDFVKLGFLSEEVNLEPIVPAFQDVFINAVEQGVSKMDFKSVTDDMSGVM
YKFPFRLPPYYALIIRSLLTLEGIALSVDPNFKILGAAYPYFARRLMEDPDPQLRESLKEMLFDNKKFKWDRLEDLLSNA
AKQTNLDLEKLLDEVINLLFSPNGGFLRNEIVEGLTNQIDLFSLKILKSLNNYLPQSIKLNTINENNNLNDLIMYVEPLR
NFLEILQKVPGYSIDIFLKRVPRLINEPYTKEMGIKIAKKVTEKGVVRLVKIAAGANI
>Mature_618_residues
MKEDFTDFIEVSGLLNYDPDTISKIYKKNPKRLLKRLWQTLIPIFAYIFSVGWDKFTGRLKNEQQARFRARELTNLLVEL
GPAFVKAGQALSTRPDIIPGILLEELSELQDQLPGFDGNKAMELIEEDLGYKINEIFLEIDKEPISAASLGQVHKAKLKN
EEIVAIKVQRPGLREQITLDLYIVRNIAYWLKNNIGLIRSDLVALIDELGKRVFEEMDYLNEAANAEKFRDMHKHNKMIA
VPKIYKEITSRRVLAMEWIDGTKLTNLEDVKKLGINPDEMIDIGVQCSLEQLLEHGFFHADPHPGNLLALEDGRLCYLDF
GMMSEVSRESRSGLIQAVVHLVNKNFDKLSQDFVKLGFLSEEVNLEPIVPAFQDVFINAVEQGVSKMDFKSVTDDMSGVM
YKFPFRLPPYYALIIRSLLTLEGIALSVDPNFKILGAAYPYFARRLMEDPDPQLRESLKEMLFDNKKFKWDRLEDLLSNA
AKQTNLDLEKLLDEVINLLFSPNGGFLRNEIVEGLTNQIDLFSLKILKSLNNYLPQSIKLNTINENNNLNDLIMYVEPLR
NFLEILQKVPGYSIDIFLKRVPRLINEPYTKEMGIKIAKKVTEKGVVRLVKIAAGANI

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=293, Percent_Identity=30.0341296928328, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI41393593, Length=263, Percent_Identity=30.0380228136882, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI217035081, Length=231, Percent_Identity=30.3030303030303, Blast_Score=116, Evalue=8e-26,
Organism=Homo sapiens, GI27363457, Length=324, Percent_Identity=29.320987654321, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI34147522, Length=299, Percent_Identity=30.1003344481605, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI217416386, Length=288, Percent_Identity=29.5138888888889, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI2367309, Length=407, Percent_Identity=27.5184275184275, Blast_Score=173, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17559152, Length=269, Percent_Identity=34.9442379182156, Blast_Score=138, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI32565180, Length=316, Percent_Identity=25.6329113924051, Blast_Score=79, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6323282, Length=238, Percent_Identity=35.7142857142857, Blast_Score=124, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6325148, Length=436, Percent_Identity=24.0825688073394, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6321319, Length=256, Percent_Identity=28.515625, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI22024280, Length=260, Percent_Identity=32.3076923076923, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24662575, Length=268, Percent_Identity=32.8358208955224, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI18859849, Length=260, Percent_Identity=28.4615384615385, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 70744; Mature: 70744

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEDFTDFIEVSGLLNYDPDTISKIYKKNPKRLLKRLWQTLIPIFAYIFSVGWDKFTGRL
CCCHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHC
KNEQQARFRARELTNLLVELGPAFVKAGQALSTRPDIIPGILLEELSELQDQLPGFDGNK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
AMELIEEDLGYKINEIFLEIDKEPISAASLGQVHKAKLKNEEIVAIKVQRPGLREQITLD
HHHHHHHHHCCCHHHHHHEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
LYIVRNIAYWLKNNIGLIRSDLVALIDELGKRVFEEMDYLNEAANAEKFRDMHKHNKMIA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEE
VPKIYKEITSRRVLAMEWIDGTKLTNLEDVKKLGINPDEMIDIGVQCSLEQLLEHGFFHA
HHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHCCCCHHHHEECCHHCCHHHHHHCCCCCC
DPHPGNLLALEDGRLCYLDFGMMSEVSRESRSGLIQAVVHLVNKNFDKLSQDFVKLGFLS
CCCCCCEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
EEVNLEPIVPAFQDVFINAVEQGVSKMDFKSVTDDMSGVMYKFPFRLPPYYALIIRSLLT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHH
LEGIALSVDPNFKILGAAYPYFARRLMEDPDPQLRESLKEMLFDNKKFKWDRLEDLLSNA
HCCEEEEECCCEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AKQTNLDLEKLLDEVINLLFSPNGGFLRNEIVEGLTNQIDLFSLKILKSLNNYLPQSIKL
HHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
NTINENNNLNDLIMYVEPLRNFLEILQKVPGYSIDIFLKRVPRLINEPYTKEMGIKIAKK
EEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHH
VTEKGVVRLVKIAAGANI
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKEDFTDFIEVSGLLNYDPDTISKIYKKNPKRLLKRLWQTLIPIFAYIFSVGWDKFTGRL
CCCHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHC
KNEQQARFRARELTNLLVELGPAFVKAGQALSTRPDIIPGILLEELSELQDQLPGFDGNK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
AMELIEEDLGYKINEIFLEIDKEPISAASLGQVHKAKLKNEEIVAIKVQRPGLREQITLD
HHHHHHHHHCCCHHHHHHEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
LYIVRNIAYWLKNNIGLIRSDLVALIDELGKRVFEEMDYLNEAANAEKFRDMHKHNKMIA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEE
VPKIYKEITSRRVLAMEWIDGTKLTNLEDVKKLGINPDEMIDIGVQCSLEQLLEHGFFHA
HHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHCCCCHHHHEECCHHCCHHHHHHCCCCCC
DPHPGNLLALEDGRLCYLDFGMMSEVSRESRSGLIQAVVHLVNKNFDKLSQDFVKLGFLS
CCCCCCEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
EEVNLEPIVPAFQDVFINAVEQGVSKMDFKSVTDDMSGVMYKFPFRLPPYYALIIRSLLT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHH
LEGIALSVDPNFKILGAAYPYFARRLMEDPDPQLRESLKEMLFDNKKFKWDRLEDLLSNA
HCCEEEEECCCEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AKQTNLDLEKLLDEVINLLFSPNGGFLRNEIVEGLTNQIDLFSLKILKSLNNYLPQSIKL
HHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
NTINENNNLNDLIMYVEPLRNFLEILQKVPGYSIDIFLKRVPRLINEPYTKEMGIKIAKK
EEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHH
VTEKGVVRLVKIAAGANI
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]