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The map label for this gene is mraY

Identifier: 126697238

GI number: 126697238

Start: 1630588

End: 1631664

Strand: Direct

Name: mraY

Synonym: P9301_19001

Alternate gene names: 126697238

Gene position: 1630588-1631664 (Clockwise)

Preceding gene: 126697237

Following gene: 126697242

Centisome position: 99.31

GC content: 26.93

Gene sequence:

>1077_bases
ATGATTGGGAAGATTAAAAAGTTTAACTTTAAATCTTTATTTATATTAAATACTTTTGCTTTAATAGTTACCTCCTATCT
TTTTAATAATTTTATTTTTACAGGAGTATACATATTATTCTTCTTTATTTCTATTTTTATAACGAAAAATGGTCTAAAGA
TTATCAAAAAATTTAATTTCCTTCAAAATATTAGGGATGAAGGCCCAACTAATCACTTTAAAAAAAGTGATACCCCAACA
ATGGGTGGGATTTTTATGATAATCCCTTTTTTAATTCTGCTTTTAATAATAACTATCAATTTAAGTTCTCTAAAATTAAT
TCTTTTATTACTTACTGTTTTTGGTTTCTTTATTACAGGATTTTTAGATGATTATTTAAGCATTAAAAAAAGAGAGAACA
CAGGTTTAAAAACAAAAGAGAAATTTATCTTACAAAGTGTCATCTCAATAATTTTTATATTGTTAGCCTACGAAAAAAAT
TTAATCAGTCCATTAATAACAATTTCTGACTCCTGGGCTATAAATATGAATATTTTCATATTGCCAGTTGCTTTTTTAGT
ACTTGTCGGCATAAGTAATTCAGTAAATTTAACTGATGGACTAGATGGATTAGCAGCTGGATGCAGTGGGATTGTCTTTT
ATGGATTAGGAACAGAAATATTACTGAAAGGACAGCAAGAACTTTTTGTTTTTAGCATTTTATGTTTTTCGATGTCAGGC
ATATGCTTAGGTTTTCTCAAGTACAATAGTTATCCTGCAAAAATATTTATGGGTGATACCGGATCTCTAAGTATAGGAGC
TATCCTAGGTTCTATAGCGTTATTAACCAATAGCATTTTTACCTTATCTATTTTCTCAGGAATATTTATTATTGAATCGT
TATCAGTAATTATTCAAGTAGGGTTTTTTAAAATTACAAAAAAATTATTTCATAGAGGTAAACGCATATTTTTAATGGCT
CCACTACACCACCACTTCGAACTTAAAGGAGTGAAGGAAGAAAAAATAGTAGAAAATTTTTGGAAAATCAACATTTTACT
TGTAATTTTAGGTATAGTTTTAAAAATCAATCTTTGA

Upstream 100 bases:

>100_bases
GGAGATTCCCAAGAGATTAGTACAATAGAGGAAGAAGAACTTTCAGCACTAATGGGAGAAAAAGAAGATTATAAAACTGA
AGAAGATCCTTCATTAGAAG

Downstream 100 bases:

>100_bases
AAAATTTGTTATGAATTTTTTTACATGGAAAGATAATGGATTAACAAGTGACTGCTCAAGTCTTGATGCAATGGCATCAA
GATTTGAAGAAACTGCCAAC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MIGKIKKFNFKSLFILNTFALIVTSYLFNNFIFTGVYILFFFISIFITKNGLKIIKKFNFLQNIRDEGPTNHFKKSDTPT
MGGIFMIIPFLILLLIITINLSSLKLILLLLTVFGFFITGFLDDYLSIKKRENTGLKTKEKFILQSVISIIFILLAYEKN
LISPLITISDSWAINMNIFILPVAFLVLVGISNSVNLTDGLDGLAAGCSGIVFYGLGTEILLKGQQELFVFSILCFSMSG
ICLGFLKYNSYPAKIFMGDTGSLSIGAILGSIALLTNSIFTLSIFSGIFIIESLSVIIQVGFFKITKKLFHRGKRIFLMA
PLHHHFELKGVKEEKIVENFWKINILLVILGIVLKINL

Sequences:

>Translated_358_residues
MIGKIKKFNFKSLFILNTFALIVTSYLFNNFIFTGVYILFFFISIFITKNGLKIIKKFNFLQNIRDEGPTNHFKKSDTPT
MGGIFMIIPFLILLLIITINLSSLKLILLLLTVFGFFITGFLDDYLSIKKRENTGLKTKEKFILQSVISIIFILLAYEKN
LISPLITISDSWAINMNIFILPVAFLVLVGISNSVNLTDGLDGLAAGCSGIVFYGLGTEILLKGQQELFVFSILCFSMSG
ICLGFLKYNSYPAKIFMGDTGSLSIGAILGSIALLTNSIFTLSIFSGIFIIESLSVIIQVGFFKITKKLFHRGKRIFLMA
PLHHHFELKGVKEEKIVENFWKINILLVILGIVLKINL
>Mature_358_residues
MIGKIKKFNFKSLFILNTFALIVTSYLFNNFIFTGVYILFFFISIFITKNGLKIIKKFNFLQNIRDEGPTNHFKKSDTPT
MGGIFMIIPFLILLLIITINLSSLKLILLLLTVFGFFITGFLDDYLSIKKRENTGLKTKEKFILQSVISIIFILLAYEKN
LISPLITISDSWAINMNIFILPVAFLVLVGISNSVNLTDGLDGLAAGCSGIVFYGLGTEILLKGQQELFVFSILCFSMSG
ICLGFLKYNSYPAKIFMGDTGSLSIGAILGSIALLTNSIFTLSIFSGIFIIESLSVIIQVGFFKITKKLFHRGKRIFLMA
PLHHHFELKGVKEEKIVENFWKINILLVILGIVLKINL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=336, Percent_Identity=37.202380952381, Blast_Score=207, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_PROM0 (A3PFJ8)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001092124.1
- STRING:   A3PFJ8
- GeneID:   4912517
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_19001
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   PMAR167546:P9301ORF_1942-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 40199; Mature: 40199

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f85e82c)-; HASH(0x1f550ec8)-; HASH(0x1bddd9d8)-; HASH(0x1f789354)-; HASH(0x1f35f0c0)-; HASH(0x1fb444d4)-; HASH(0x1f97a0d4)-; HASH(0x1fa7d054)-; HASH(0x1edcf29c)-; HASH(0x1f6ba5c8)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKIKKFNFKSLFILNTFALIVTSYLFNNFIFTGVYILFFFISIFITKNGLKIIKKFNF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LQNIRDEGPTNHFKKSDTPTMGGIFMIIPFLILLLIITINLSSLKLILLLLTVFGFFITG
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
FLDDYLSIKKRENTGLKTKEKFILQSVISIIFILLAYEKNLISPLITISDSWAINMNIFI
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCEEEEEEHHH
LPVAFLVLVGISNSVNLTDGLDGLAAGCSGIVFYGLGTEILLKGQQELFVFSILCFSMSG
HHHHHHHHHCCCCCCCCCCCCHHHHHCCCCEEEEECCHHHEECCCHHHHHHHHHHHHHHH
ICLGFLKYNSYPAKIFMGDTGSLSIGAILGSIALLTNSIFTLSIFSGIFIIESLSVIIQV
HHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFFKITKKLFHRGKRIFLMAPLHHHFELKGVKEEKIVENFWKINILLVILGIVLKINL
HHHHHHHHHHHCCCEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MIGKIKKFNFKSLFILNTFALIVTSYLFNNFIFTGVYILFFFISIFITKNGLKIIKKFNF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LQNIRDEGPTNHFKKSDTPTMGGIFMIIPFLILLLIITINLSSLKLILLLLTVFGFFITG
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
FLDDYLSIKKRENTGLKTKEKFILQSVISIIFILLAYEKNLISPLITISDSWAINMNIFI
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCEEEEEEHHH
LPVAFLVLVGISNSVNLTDGLDGLAAGCSGIVFYGLGTEILLKGQQELFVFSILCFSMSG
HHHHHHHHHCCCCCCCCCCCCHHHHHCCCCEEEEECCHHHEECCCHHHHHHHHHHHHHHH
ICLGFLKYNSYPAKIFMGDTGSLSIGAILGSIALLTNSIFTLSIFSGIFIIESLSVIIQV
HHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFFKITKKLFHRGKRIFLMAPLHHHFELKGVKEEKIVENFWKINILLVILGIVLKINL
HHHHHHHHHHHCCCEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA