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The map label for this gene is clpX

Identifier: 126697185

GI number: 126697185

Start: 1572250

End: 1573617

Strand: Direct

Name: clpX

Synonym: P9301_18471

Alternate gene names: 126697185

Gene position: 1572250-1573617 (Clockwise)

Preceding gene: 126697184

Following gene: 126697186

Centisome position: 95.76

GC content: 33.19

Gene sequence:

>1368_bases
ATGGCTAAATTCGACGCCCATCTTAAATGTTCATTTTGCGGGAAATCACAAGACCAAGTAAGAAAGCTTATTGCTGGTCC
TGGGGTTTATATCTGTGATGAGTGCATAGATCTTTGTAATGAAATTCTCGATGAAGAACTACTTGATAATCAAGCGAACA
CTAATAACTCTCCGCAAGTAAAAAAGAAATTACCAACTGATAATCCAAAAAAATCTGTTCCTTTAGAATTAACCTCTATT
CCTAAGCCATTAGAAATTAAAAGTTTTCTAGATAATCAAGTTGTTGGACAAGAATCTGCAAAAAAAATATTATCTGTAGC
CGTATACAATCACTACAAGCGATTAGCTTGGAAATTTAAAGAAGAAAATAAAAATAGCAATTCAAAAGATTCACAAGCAA
CTAAATTACAAAAATCAAATATTTTACTCATCGGCCCTACTGGAAGTGGGAAAACATTATTGGCGCAAACTTTAGCAGAG
TTTCTGGATGTTCCTTTTGCAGTAGCTGATGCAACGACTTTGACAGAAGCTGGATATGTTGGGGAGGATGTTGAAAATAT
ACTTTTAAGACTTCTACAAAAATCAGAAATGAATGTAGAACTAGCTCAAAAAGGAATAATTTATATTGATGAAATAGATA
AAATTGCGAGAAAAAGCGAAAATCCTTCAATTACTAGAGATGTCTCTGGTGAAGGAGTACAGCAAGCATTATTAAAAATG
CTTGAAGGAACAATTGCTAATGTGCCACCACAAGGAGGAAGAAAACATCCTTATCATGACTGCATCCAAATTGATACGAG
TCAAATATTATTTATTTGTGGGGGAGCTTTTATAGGTTTAGAGGATATCGTTCAAAAGCGAATGGGTAAACACTCTATAG
GATTTACCACCAATTCAGATCAAAACAAAGTTGATACAAAAAAAATAGTAGATCCAAGAGATGCCCTGAAAAATCTAGAA
TTAGATGACTTAGTGAAATATGGCCTAATTCCAGAATTTATTGGAAGAATTCCGGTTTGTGCTGTATTAGATCGTCTTAC
AAAGGAAACTTTAGAATCTATTTTGACTCAACCAAGAGATGCATTAGTAAAGCAATTCAAAACTTTGCTAAGTATGGATA
ATGTTGAATTATCGTTTGAGCCTGATTCTGTTGAAGCAATAGCAAATGAGGCATATAAAAGAAAAACAGGTGCAAGAGCA
TTAAGGTCAATAATTGAAGAGCTAATGCTAGACATAATGTACACTTTGCCTTCTGAAGAAAATGTAAAAGAATTCACAAT
TACGAAAAAAATGGTAGATAATTTGTTCTCATCTAAAATTGTTAAACTACCTTCAGGATCAAAAAGAGTCATTAAAGAGT
CTGCATAA

Upstream 100 bases:

>100_bases
AATACTGATTTTTTAAGAATATGATGACGAATTGATATTTATAAGCAATCCTAGTGAATAGGGAATATTAAACACCTTAC
ACTTTAAAAACTTATAATCG

Downstream 100 bases:

>100_bases
AATTAGAGTTTAATTTTTTTAATTTAATCCCGAATTTTTCTAATGAATGAAAAATAAATGCCAAATATACATAAGCCTTT
TCATCAAAAATATAGACCAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELLDNQANTNNSPQVKKKLPTDNPKKSVPLELTSI
PKPLEIKSFLDNQVVGQESAKKILSVAVYNHYKRLAWKFKEENKNSNSKDSQATKLQKSNILLIGPTGSGKTLLAQTLAE
FLDVPFAVADATTLTEAGYVGEDVENILLRLLQKSEMNVELAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRMGKHSIGFTTNSDQNKVDTKKIVDPRDALKNLE
LDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTQPRDALVKQFKTLLSMDNVELSFEPDSVEAIANEAYKRKTGARA
LRSIIEELMLDIMYTLPSEENVKEFTITKKMVDNLFSSKIVKLPSGSKRVIKESA

Sequences:

>Translated_455_residues
MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELLDNQANTNNSPQVKKKLPTDNPKKSVPLELTSI
PKPLEIKSFLDNQVVGQESAKKILSVAVYNHYKRLAWKFKEENKNSNSKDSQATKLQKSNILLIGPTGSGKTLLAQTLAE
FLDVPFAVADATTLTEAGYVGEDVENILLRLLQKSEMNVELAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRMGKHSIGFTTNSDQNKVDTKKIVDPRDALKNLE
LDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTQPRDALVKQFKTLLSMDNVELSFEPDSVEAIANEAYKRKTGARA
LRSIIEELMLDIMYTLPSEENVKEFTITKKMVDNLFSSKIVKLPSGSKRVIKESA
>Mature_454_residues
AKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELLDNQANTNNSPQVKKKLPTDNPKKSVPLELTSIP
KPLEIKSFLDNQVVGQESAKKILSVAVYNHYKRLAWKFKEENKNSNSKDSQATKLQKSNILLIGPTGSGKTLLAQTLAEF
LDVPFAVADATTLTEAGYVGEDVENILLRLLQKSEMNVELAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKML
EGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRMGKHSIGFTTNSDQNKVDTKKIVDPRDALKNLEL
DDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTQPRDALVKQFKTLLSMDNVELSFEPDSVEAIANEAYKRKTGARAL
RSIIEELMLDIMYTLPSEENVKEFTITKKMVDNLFSSKIVKLPSGSKRVIKESA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=307, Percent_Identity=49.5114006514658, Blast_Score=289, Evalue=4e-78,
Organism=Escherichia coli, GI1786642, Length=431, Percent_Identity=55.4524361948956, Blast_Score=470, Evalue=1e-134,
Organism=Escherichia coli, GI1790366, Length=217, Percent_Identity=31.3364055299539, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71982908, Length=295, Percent_Identity=45.4237288135593, Blast_Score=269, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI71982905, Length=297, Percent_Identity=45.7912457912458, Blast_Score=268, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI71988663, Length=413, Percent_Identity=38.7409200968523, Blast_Score=254, Evalue=5e-68,
Organism=Caenorhabditis elegans, GI71988660, Length=253, Percent_Identity=40.7114624505929, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=431, Percent_Identity=37.122969837587, Blast_Score=246, Evalue=4e-66,
Organism=Drosophila melanogaster, GI24648291, Length=317, Percent_Identity=46.3722397476341, Blast_Score=285, Evalue=6e-77,
Organism=Drosophila melanogaster, GI24648289, Length=317, Percent_Identity=46.3722397476341, Blast_Score=284, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_PROM0 (A3PFE5)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001092071.1
- ProteinModelPortal:   A3PFE5
- STRING:   A3PFE5
- GeneID:   4911049
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_18471
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- BioCyc:   PMAR167546:P9301ORF_1888-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 50597; Mature: 50466

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELLDNQANTNNSPQV
CCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
KKKLPTDNPKKSVPLELTSIPKPLEIKSFLDNQVVGQESAKKILSVAVYNHYKRLAWKFK
HHCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EENKNSNSKDSQATKLQKSNILLIGPTGSGKTLLAQTLAEFLDVPFAVADATTLTEAGYV
HHCCCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCC
GEDVENILLRLLQKSEMNVELAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
CHHHHHHHHHHHHHHCCCHHHHHCCCEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRMGKHSIGFTTNSD
HHHHHCCCCCCCCCCCCCHHHHEECCHHEEEECCCHHCCHHHHHHHHHCCCCCCCCCCCC
QNKVDTKKIVDPRDALKNLELDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTQPRD
CCCCCHHHCCCHHHHHHCCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHH
ALVKQFKTLLSMDNVELSFEPDSVEAIANEAYKRKTGARALRSIIEELMLDIMYTLPSEE
HHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NVKEFTITKKMVDNLFSSKIVKLPSGSKRVIKESA
CHHHHHHHHHHHHHHHHHCEEECCCCCHHHHCCCC
>Mature Secondary Structure 
AKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELLDNQANTNNSPQV
CCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
KKKLPTDNPKKSVPLELTSIPKPLEIKSFLDNQVVGQESAKKILSVAVYNHYKRLAWKFK
HHCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EENKNSNSKDSQATKLQKSNILLIGPTGSGKTLLAQTLAEFLDVPFAVADATTLTEAGYV
HHCCCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCC
GEDVENILLRLLQKSEMNVELAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
CHHHHHHHHHHHHHHCCCHHHHHCCCEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRMGKHSIGFTTNSD
HHHHHCCCCCCCCCCCCCHHHHEECCHHEEEECCCHHCCHHHHHHHHHCCCCCCCCCCCC
QNKVDTKKIVDPRDALKNLELDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTQPRD
CCCCCHHHCCCHHHHHHCCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHH
ALVKQFKTLLSMDNVELSFEPDSVEAIANEAYKRKTGARALRSIIEELMLDIMYTLPSEE
HHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NVKEFTITKKMVDNLFSSKIVKLPSGSKRVIKESA
CHHHHHHHHHHHHHHHHHCEEECCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA