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The map label for this gene is infC [H]

Identifier: 126697165

GI number: 126697165

Start: 1548328

End: 1548900

Strand: Direct

Name: infC [H]

Synonym: P9301_18271

Alternate gene names: 126697165

Gene position: 1548328-1548900 (Clockwise)

Preceding gene: 126697164

Following gene: 126697166

Centisome position: 94.3

GC content: 34.55

Gene sequence:

>573_bases
ATGCCCCCACGCCCACGCTTTGACCGAAGAGCTCCAGTTAGAGAGCTACCAAATATAAATGAAAGAATAAAATACCCTCA
ATTGAGAGTCGTTGATTCAGATGGAAAACAATTAGGCGTCATAGATAGATTAAAAGCATTAGAAATCGCATCTCAAAGAG
AACTTGATTTAGTTTTGGTGAGCGAAAAAGCAAATCCTCCTGTTTGTAGAATCATGGACTATGGGAAATATAAATTTGAA
CAAGAAAAAAAAGCTAAAGAAGCAAGAAAAAAATCTCATCAAACAGAAGTTAAAGAAGTAAAAATGAGGTACAAAATTGA
CAAGCATGATTATGATGTGCGGATTGGTCAAGCTACTAAATTTCTAAAATCGGGAGACAAGGTAAAATGCACTGTAATTT
TTAGGGGAAGAGAAATTCAACACTCAAATTTAGCTGAGACTCTTCTTTTAAGAATGGCTAATGATTTAGAAGAGCAATCA
GAAGTTCAACAAAAACCAAAAAGAGAAGGAAGAAACATGATTATGTTTTTAAGTCCCCGTAAAACTCCTCTCATTAAAAA
AGATGATGCGTGA

Upstream 100 bases:

>100_bases
ACCCGCTAAAAGATGCAATAATTAAGATAGAGTCTTTTTTAAGCTAACTTTATAAAAATAGATTTTGTTCATCATCCAAT
CAATTTATTTAATTAACTGA

Downstream 100 bases:

>100_bases
TAAACTTTTATCAAAAAATATGACGAATGTTAAAGTGTCACTATATCAAAAAATAAATTAGTAAGGATTTTTCTAAAGTG
AGATTCCATATTCAACAAGA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MPPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLKALEIASQRELDLVLVSEKANPPVCRIMDYGKYKFE
QEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATKFLKSGDKVKCTVIFRGREIQHSNLAETLLLRMANDLEEQS
EVQQKPKREGRNMIMFLSPRKTPLIKKDDA

Sequences:

>Translated_190_residues
MPPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLKALEIASQRELDLVLVSEKANPPVCRIMDYGKYKFE
QEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATKFLKSGDKVKCTVIFRGREIQHSNLAETLLLRMANDLEEQS
EVQQKPKREGRNMIMFLSPRKTPLIKKDDA
>Mature_189_residues
PPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLKALEIASQRELDLVLVSEKANPPVCRIMDYGKYKFEQ
EKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATKFLKSGDKVKCTVIFRGREIQHSNLAETLLLRMANDLEEQSE
VQQKPKREGRNMIMFLSPRKTPLIKKDDA

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=167, Percent_Identity=44.9101796407186, Blast_Score=128, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 22271; Mature: 22140

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLKALEIASQRELDLVLV
CCCCCCCCCCCCHHHCCCCHHHCCCCEEEEECCCCCEECHHHHHHHHHHHCCCCEEEEEE
SEKANPPVCRIMDYGKYKFEQEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATK
ECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECHHHH
FLKSGDKVKCTVIFRGREIQHSNLAETLLLRMANDLEEQSEVQQKPKREGRNMIMFLSPR
HHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
KTPLIKKDDA
CCCCCCCCCC
>Mature Secondary Structure 
PPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLKALEIASQRELDLVLV
CCCCCCCCCCCHHHCCCCHHHCCCCEEEEECCCCCEECHHHHHHHHHHHCCCCEEEEEE
SEKANPPVCRIMDYGKYKFEQEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATK
ECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECHHHH
FLKSGDKVKCTVIFRGREIQHSNLAETLLLRMANDLEEQSEVQQKPKREGRNMIMFLSPR
HHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
KTPLIKKDDA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA