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The map label for this gene is alr [H]

Identifier: 126697057

GI number: 126697057

Start: 1454261

End: 1455460

Strand: Reverse

Name: alr [H]

Synonym: P9301_17191

Alternate gene names: 126697057

Gene position: 1455460-1454261 (Counterclockwise)

Preceding gene: 126697059

Following gene: 126697054

Centisome position: 88.65

GC content: 30.25

Gene sequence:

>1200_bases
ATGCAAATTCGGAAATCTAACCAGGAATTTAATTTTGATAAATATTCATTTTTTAAACAAGATATAGATCCAAAACAAAG
GGCATGGATTGAAGTTAAAGGCAAAGCATTGGAGACAAATGTAAGGCAATTAAGAACAAAATTAAGAAAAAATTGTCAAT
TTATGGCGGTTGTCAAAGCTGATGGATATGGACATGATGCAAAAGTAGTATGTGACTACGCAATTAAAGGCGGAGCTTCG
GAATTAGGCGTTGCAACTTTAGAAGAAGGGATTAAGCTACGTTCTTTTGGAGTTAAAAAACCAATTCTTATTTTAGGAAA
TCTATATACAAAAAGAGATTTAATAATATCCTTTAAAAATGACCTTATGCCAACTATAAGTAGTATAAGAGAGTGTTTAG
TTTGCAATAATATCGGGAAGCACTTTGGGTTAAAATTTTCTTTACATCTTAAGGTTGATACTGGAATGTCAAGATTAGGA
TTTGAATCTAAAAAATTTATTCAGCAATTTGAAAAAATAAAATCTTTTGAGAACATTTCAATAGAAGGAATATATAGTCA
TTTATCATCTGCAGATGAAAATAACGCATTAGATTCTCAAAGTATTACACAATCACAAAGACTGAAGTTCAATGAATTAT
TAAAGCAAATTAATTTTGATAGAAATAATGAAATTAAGATTCATTTGGCTAATTCAGCGGGCATGCTTCTTAGCAAAGAT
TTTCATTTTCACATGGTACGTGTTGGGCTTTCAATGTACGGATACAGTCCTCTAGCTAAAATAGATAAAAATTTATTACT
TAAACCAGCTTTATCTTTGAAGGTCAAAGTAGCTTTTATAAGAACTATTGATAAAGGGGTAAGTGTAAGTTATGGAGGCA
AATTTGTAAGTAATAGAAAAACTAAGTTAGCTGTATTAAGTATTGGTTATGCAGATGGTGTACCAAGAAATCTTTCAGGC
AAGATTAAAGTTATTCATAATAATAAATTTTATCCTCAAGTTGGATCTATAACTATGGACCAAATGATGGTAGACATAAC
AGATTCCAAGGAAATTAAAGTTGGTAGTATCATGGTATTACTAGGATCTGATGGAGATAAAACAATTTCTCCTCTTGAAT
GGTCAAGAAAATCTAATACTATCCCCTGGGAAATTCTTTGTTCTTTTAAAAATAGATTACCGAAAGTTCAAGTAGATTAG

Upstream 100 bases:

>100_bases
TAAGATGCATTTAAAACTAGAGTCTGGCCCATGCCAAAATACAATTTACATGTCATGCTAACTGTATATTTCAATAAGCG
CATACAATTGTGCAAAGTTA

Downstream 100 bases:

>100_bases
ACATTTCGAATAAATAAAAAATTTTGAATGTTTGCAGAAAAATTGATAATGTATAAGAACTGGAGAGGTGGCTGAGTGGT
TGAAAGCGGCTCCCTGCTAA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MQIRKSNQEFNFDKYSFFKQDIDPKQRAWIEVKGKALETNVRQLRTKLRKNCQFMAVVKADGYGHDAKVVCDYAIKGGAS
ELGVATLEEGIKLRSFGVKKPILILGNLYTKRDLIISFKNDLMPTISSIRECLVCNNIGKHFGLKFSLHLKVDTGMSRLG
FESKKFIQQFEKIKSFENISIEGIYSHLSSADENNALDSQSITQSQRLKFNELLKQINFDRNNEIKIHLANSAGMLLSKD
FHFHMVRVGLSMYGYSPLAKIDKNLLLKPALSLKVKVAFIRTIDKGVSVSYGGKFVSNRKTKLAVLSIGYADGVPRNLSG
KIKVIHNNKFYPQVGSITMDQMMVDITDSKEIKVGSIMVLLGSDGDKTISPLEWSRKSNTIPWEILCSFKNRLPKVQVD

Sequences:

>Translated_399_residues
MQIRKSNQEFNFDKYSFFKQDIDPKQRAWIEVKGKALETNVRQLRTKLRKNCQFMAVVKADGYGHDAKVVCDYAIKGGAS
ELGVATLEEGIKLRSFGVKKPILILGNLYTKRDLIISFKNDLMPTISSIRECLVCNNIGKHFGLKFSLHLKVDTGMSRLG
FESKKFIQQFEKIKSFENISIEGIYSHLSSADENNALDSQSITQSQRLKFNELLKQINFDRNNEIKIHLANSAGMLLSKD
FHFHMVRVGLSMYGYSPLAKIDKNLLLKPALSLKVKVAFIRTIDKGVSVSYGGKFVSNRKTKLAVLSIGYADGVPRNLSG
KIKVIHNNKFYPQVGSITMDQMMVDITDSKEIKVGSIMVLLGSDGDKTISPLEWSRKSNTIPWEILCSFKNRLPKVQVD
>Mature_399_residues
MQIRKSNQEFNFDKYSFFKQDIDPKQRAWIEVKGKALETNVRQLRTKLRKNCQFMAVVKADGYGHDAKVVCDYAIKGGAS
ELGVATLEEGIKLRSFGVKKPILILGNLYTKRDLIISFKNDLMPTISSIRECLVCNNIGKHFGLKFSLHLKVDTGMSRLG
FESKKFIQQFEKIKSFENISIEGIYSHLSSADENNALDSQSITQSQRLKFNELLKQINFDRNNEIKIHLANSAGMLLSKD
FHFHMVRVGLSMYGYSPLAKIDKNLLLKPALSLKVKVAFIRTIDKGVSVSYGGKFVSNRKTKLAVLSIGYADGVPRNLSG
KIKVIHNNKFYPQVGSITMDQMMVDITDSKEIKVGSIMVLLGSDGDKTISPLEWSRKSNTIPWEILCSFKNRLPKVQVD

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=351, Percent_Identity=31.3390313390313, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787439, Length=369, Percent_Identity=27.10027100271, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 45059; Mature: 45059

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIRKSNQEFNFDKYSFFKQDIDPKQRAWIEVKGKALETNVRQLRTKLRKNCQFMAVVKA
CCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEE
DGYGHDAKVVCDYAIKGGASELGVATLEEGIKLRSFGVKKPILILGNLYTKRDLIISFKN
CCCCCCCEEEEEEEECCCCCCCCHHHHHCCCEEEECCCCCCEEEEECCCCCCEEEEEECH
DLMPTISSIRECLVCNNIGKHFGLKFSLHLKVDTGMSRLGFESKKFIQQFEKIKSFENIS
HHHHHHHHHHHHHHHHCCHHHCCEEEEEEEEEECCCHHCCCCHHHHHHHHHHHHHHCCCC
IEGIYSHLSSADENNALDSQSITQSQRLKFNELLKQINFDRNNEIKIHLANSAGMLLSKD
HHHHHHHHCCCCCCCCCCCHHHHHHHCCCHHHHHHHCCCCCCCEEEEEEECCCCCEEECC
FHFHMVRVGLSMYGYSPLAKIDKNLLLKPALSLKVKVAFIRTIDKGVSVSYGGKFVSNRK
CCEEEEEHHHHHHCCCCHHHHCHHHEECCCCCEEEEEEEEEECCCCCEEECCCEEECCCC
TKLAVLSIGYADGVPRNLSGKIKVIHNNKFYPQVGSITMDQMMVDITDSKEIKVGSIMVL
EEEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCEEEEHEEEEECCCCCEEEEEEEEE
LGSDGDKTISPLEWSRKSNTIPWEILCSFKNRLPKVQVD
EECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEECC
>Mature Secondary Structure
MQIRKSNQEFNFDKYSFFKQDIDPKQRAWIEVKGKALETNVRQLRTKLRKNCQFMAVVKA
CCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEE
DGYGHDAKVVCDYAIKGGASELGVATLEEGIKLRSFGVKKPILILGNLYTKRDLIISFKN
CCCCCCCEEEEEEEECCCCCCCCHHHHHCCCEEEECCCCCCEEEEECCCCCCEEEEEECH
DLMPTISSIRECLVCNNIGKHFGLKFSLHLKVDTGMSRLGFESKKFIQQFEKIKSFENIS
HHHHHHHHHHHHHHHHCCHHHCCEEEEEEEEEECCCHHCCCCHHHHHHHHHHHHHHCCCC
IEGIYSHLSSADENNALDSQSITQSQRLKFNELLKQINFDRNNEIKIHLANSAGMLLSKD
HHHHHHHHCCCCCCCCCCCHHHHHHHCCCHHHHHHHCCCCCCCEEEEEEECCCCCEEECC
FHFHMVRVGLSMYGYSPLAKIDKNLLLKPALSLKVKVAFIRTIDKGVSVSYGGKFVSNRK
CCEEEEEHHHHHHCCCCHHHHCHHHEECCCCCEEEEEEEEEECCCCCEEECCCEEECCCC
TKLAVLSIGYADGVPRNLSGKIKVIHNNKFYPQVGSITMDQMMVDITDSKEIKVGSIMVL
EEEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCEEEEHEEEEECCCCCEEEEEEEEE
LGSDGDKTISPLEWSRKSNTIPWEILCSFKNRLPKVQVD
EECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]