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The map label for this gene is atpA

Identifier: 126696979

GI number: 126696979

Start: 1373011

End: 1374528

Strand: Reverse

Name: atpA

Synonym: P9301_16411

Alternate gene names: 126696979

Gene position: 1374528-1373011 (Counterclockwise)

Preceding gene: 126696980

Following gene: 126696978

Centisome position: 83.72

GC content: 38.6

Gene sequence:

>1518_bases
ATGGTATCTATACGCCCTGATGAAATCAGTTCAATCTTAAAACAACAAATAACTGATTATGACCAATCTGTAAGTGTTAG
CAATGTAGGAACTGTTCTGCAAATCGGTGATGGCATTGCAAGAATATATGGCTTAGATCAGGTCATGGCAGGTGAGCTAT
TGGAATTTGAAGATGGTACCGAAGGTATAGCTTTAAATCTTGAAGATGATAATGTTGGGGCCGTTTTGATGGGAGAGGCA
CTTGGTGTCCAAGAAGGGAGTAACGTTAAGTCCACAGGTAAAATTGCATCTGTTCCCGTTGGTGAAGCAATGCAGGGGAG
AGTTGTTAACCCTCTCGGACAACCAATAGATGGGAAAGGGGAAATTCCAACAAGTGATACTAGATTGATTGAAGAAATGG
CTCCTGGAATAATCAAGAGAAGATCAGTGCATGAGCCAATGCAAACAGGTATTACATCTATTGATGCAATGATTCCTGTT
GGAAGAGGTCAAAGAGAATTAATTATTGGTGATAGACAAACTGGAAAGTCGGCAATTGCTATCGATACGATAATTAACCA
AAAAGGTCAAGACGTAGTATGTGTTTACGTAGCTATTGGTCAGAAGTCAGCATCAGTAGCAAATATAGTAGAGGTATTAA
GAGAGAGGGGAGCCCTAGATTATACAGTAGTTGTTAGTGCAGGAGCTTCAGAACCAGCTGCTTTACAGTACTTAGCACCT
TATACCGGTGCAGCAATTGCTGAACATTTTATGTATCAGGGTAAAGCAACACTTGTTATTTATGATGATCTAACGAAACA
AGCTCAGGCTTATAGACAAATGTCTCTCCTTTTAAAAAGACCACCAGGAAGAGAGGCTTATCCAGGAGATGTTTTCTACT
TACACAGTAGATTACTAGAAAGAGCAGCAAAACTTTCTGATGCTATGGGAGGGGGATCTATGACAGCTCTTCCAATTATT
GAAACTCAGGCAGGGGACGTTTCTGCTTACATTCCAACTAATGTTATTTCAATTACAGATGGACAAATATTCTTGAGTGC
AGATTTATTTAACTCAGGATTAAGACCAGCTATTAATGTTGGTATTTCCGTTAGCCGTGTTGGAGGAGCCGCTCAGACAA
AAGCAATTAAAAAAATTGCAGGAACTTTAAAATTAGAACTCGCACAGTTTGATGAACTAGCTGCTTTTTCTCAATTTGCA
TCTGATCTTGATGAAGCAACTCAGCAACAACTTGAACGGGGCAAAAGATTAAGAGAGTTATTAAAGCAACCTCAATTCTC
TCCGTTGAACCTTGCAGAACAAGTTGCAGTTGTTTATGCAGGAGTTAAAGGTCTTATTGATGAGGTTCCTGTTGAAGATG
TTACTAAATTTGCAACTGAACTTCGCGAATACTTAAAGCTAAATAAAGCGGAATTTATAGAAGAGATTCTTAAAGAAAAG
AAATTAAATGATGGACTAGAAGCGACGCTAAAAGAAGTGATAAATGAAGTTAAATCATCAATGCTTGCCACAGTTTAA

Upstream 100 bases:

>100_bases
AGGATCAAAAGTAATTGATGCTTCTCTTGCTTCACAAATAAGAAAACTTGGCTTATCCCTTTCCAAGTAACTTTTAAATC
AACCTTAAATTCTTAAATCC

Downstream 100 bases:

>100_bases
ATTTATTAAGGAGATACCATGGCAAATCTTAAAGAGATTAGAGATCGAATCGTTTCCGTTAAAAATACAAGAAAAATAAC
GGAGGCCATGAGACTTGTTG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGTEGIALNLEDDNVGAVLMGEA
LGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKGEIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPV
GRGQRELIIGDRQTGKSAIAIDTIINQKGQDVVCVYVAIGQKSASVANIVEVLRERGALDYTVVVSAGASEPAALQYLAP
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLKRPPGREAYPGDVFYLHSRLLERAAKLSDAMGGGSMTALPII
ETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQQQLERGKRLRELLKQPQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFATELREYLKLNKAEFIEEILKEK
KLNDGLEATLKEVINEVKSSMLATV

Sequences:

>Translated_505_residues
MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGTEGIALNLEDDNVGAVLMGEA
LGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKGEIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPV
GRGQRELIIGDRQTGKSAIAIDTIINQKGQDVVCVYVAIGQKSASVANIVEVLRERGALDYTVVVSAGASEPAALQYLAP
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLKRPPGREAYPGDVFYLHSRLLERAAKLSDAMGGGSMTALPII
ETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQQQLERGKRLRELLKQPQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFATELREYLKLNKAEFIEEILKEK
KLNDGLEATLKEVINEVKSSMLATV
>Mature_505_residues
MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGTEGIALNLEDDNVGAVLMGEA
LGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKGEIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPV
GRGQRELIIGDRQTGKSAIAIDTIINQKGQDVVCVYVAIGQKSASVANIVEVLRERGALDYTVVVSAGASEPAALQYLAP
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLKRPPGREAYPGDVFYLHSRLLERAAKLSDAMGGGSMTALPII
ETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQQQLERGKRLRELLKQPQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFATELREYLKLNKAEFIEEILKEK
KLNDGLEATLKEVINEVKSSMLATV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=496, Percent_Identity=60.2822580645161, Blast_Score=595, Evalue=1e-170,
Organism=Homo sapiens, GI4757810, Length=496, Percent_Identity=60.2822580645161, Blast_Score=595, Evalue=1e-170,
Organism=Homo sapiens, GI19913428, Length=300, Percent_Identity=29.6666666666667, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI19913426, Length=299, Percent_Identity=29.0969899665552, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI32189394, Length=407, Percent_Identity=24.0786240786241, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1790172, Length=504, Percent_Identity=54.3650793650794, Blast_Score=556, Evalue=1e-159,
Organism=Escherichia coli, GI1790170, Length=418, Percent_Identity=24.8803827751196, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788251, Length=336, Percent_Identity=29.4642857142857, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=495, Percent_Identity=59.3939393939394, Blast_Score=598, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI71988080, Length=495, Percent_Identity=59.3939393939394, Blast_Score=598, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI71988074, Length=495, Percent_Identity=56.1616161616162, Blast_Score=554, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI17570191, Length=292, Percent_Identity=29.1095890410959, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17510931, Length=296, Percent_Identity=27.7027027027027, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=431, Percent_Identity=23.8979118329466, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71988068, Length=78, Percent_Identity=43.5897435897436, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=60, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=495, Percent_Identity=58.1818181818182, Blast_Score=581, Evalue=1e-166,
Organism=Saccharomyces cerevisiae, GI6319603, Length=299, Percent_Identity=29.0969899665552, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6322581, Length=395, Percent_Identity=25.8227848101266, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=59.2079207920792, Blast_Score=600, Evalue=1e-172,
Organism=Drosophila melanogaster, GI281361666, Length=294, Percent_Identity=28.9115646258503, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24646341, Length=294, Percent_Identity=28.9115646258503, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI17136796, Length=294, Percent_Identity=28.9115646258503, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24638766, Length=437, Percent_Identity=24.9427917620137, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28574560, Length=400, Percent_Identity=26, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_PROM0 (A3PET9)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001091865.1
- ProteinModelPortal:   A3PET9
- SMR:   A3PET9
- STRING:   A3PET9
- GeneID:   4911138
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_16411
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- ProtClustDB:   PRK09281
- BioCyc:   PMAR167546:P9301ORF_1673-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54277; Mature: 54277

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGT
CCCCCHHHHHHHHHHHHHCCCCCCCHHHCCHHEECCCHHHHHHHHHHHHHHHHHCCCCCC
EGIALNLEDDNVGAVLMGEALGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKG
CCEEEEECCCCCCEEEECCHHCCCCCCCCCCCCCEECCCCCCHHCCCCCCCCCCCCCCCC
EIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPVGRGQRELIIGDRQTGKSAIA
CCCCHHHHHHHHHCCHHHHHHHHCCHHHHCHHHHHHHCCCCCCCCEEEECCCCCCCCEEE
IDTIINQKGQDVVCVYVAIGQKSASVANIVEVLRERGALDYTVVVSAGASEPAALQYLAP
HHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHCC
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLKRPPGREAYPGDVFYLHSRLLE
CHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLSDAMGGGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINV
HHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEEEHHHCCCCCCHHHC
GISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQQQLERGKRLREL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQPQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFATELREYLKLNKAEFIEEILKEK
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KLNDGLEATLKEVINEVKSSMLATV
CCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGT
CCCCCHHHHHHHHHHHHHCCCCCCCHHHCCHHEECCCHHHHHHHHHHHHHHHHHCCCCCC
EGIALNLEDDNVGAVLMGEALGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKG
CCEEEEECCCCCCEEEECCHHCCCCCCCCCCCCCEECCCCCCHHCCCCCCCCCCCCCCCC
EIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPVGRGQRELIIGDRQTGKSAIA
CCCCHHHHHHHHHCCHHHHHHHHCCHHHHCHHHHHHHCCCCCCCCEEEECCCCCCCCEEE
IDTIINQKGQDVVCVYVAIGQKSASVANIVEVLRERGALDYTVVVSAGASEPAALQYLAP
HHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHCC
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLKRPPGREAYPGDVFYLHSRLLE
CHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLSDAMGGGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINV
HHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEEEHHHCCCCCCHHHC
GISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQQQLERGKRLREL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQPQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFATELREYLKLNKAEFIEEILKEK
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KLNDGLEATLKEVINEVKSSMLATV
CCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA