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The map label for this gene is rnr [C]

Identifier: 126696330

GI number: 126696330

Start: 863707

End: 864891

Strand: Direct

Name: rnr [C]

Synonym: P9301_09921

Alternate gene names: 126696330

Gene position: 863707-864891 (Clockwise)

Preceding gene: 126696329

Following gene: 126696331

Centisome position: 52.6

GC content: 22.62

Gene sequence:

>1185_bases
TTGAAAGATTTAACTGATTTAAAAACATATATTATTGACTCTGATGATCCACATGAGGTCGATGACGCTATTTCATTAGA
AATAAAAGAAGGAAATAAAAAAAATTTATGGATACATATTAGTAATCCATGCAAACTCTTTTTGCATGACTCTAATGTTG
ATTTAAATGCAAGAAAGAGAAATAGCAGTTTATATTTAATTGATCAATATGTCCCAATGCTTCCTAATGATATTCTTGAA
AAGGCAAATCTAGCTCAAAATAAAGTTTCAGAAACTATTAGTGCAGCAATAGAATTCAATGACGATGGATCAATAAATAA
ATATGAAATAACCGAAGCAATAATAAAGCCAAAATATCAATTAACATATGAAGATGCAAATGAAATATTAGAAATAGAAC
CTAAAGAAGAAATAGAATTAATTGAGATTAAAAATTTATTAAAAAAAAGTATTACATTCAGAAAGAAACAAGGAGCAATT
ATTTTTGAAAGTCCTAATAATAAAATTAAATTATTTGAAGATAAGATTATATTAACTAAATTAGAGAAAACAATATCTCA
AATTATAGTTGCAGAATCAATGATATTAATGGGTTATGTAACAAGTTTATTTTTAGATAAATATAATTTAGCGGCTGCAT
TTAGAATTCAAAAAATAAACTGCAATCCATCTGAAATACTCAATAGATACATTGATAGTGATATTAAATATATAATATTA
AAACAATATATGGGAAGAAGTTACATAACTATTAAGCCAGGAATCCATGAATCATTAGGCCTTAAAATGTATGTACAATG
TACATCCCCATTGAGAAGATATCTTGATTTAATTATACAAAGGCAAGTCTATAACAAAATTAATAATTACGAAGTTCTAA
GTAAAGATTCAGTCTCTAAGATTATCGATTATTCAAAAAATAGACAATCAGAGAATAATAATATATTTAAAAATGATAAA
TTTAAGTATTTAAGATTATTTTTTAATAATGAAAAAAAACTTTTTTATAACATAATATTCGTTAAGTGGATTAATCATAA
AAAAAATATAGCTTTGGTTTATTTTCCAGATTATTCACTAGAAATACTTATTACCCTTTTTATTTCAATAGAAATATATA
GTAATAAAATATATAAAGTTAAATATATTATAAATGATAGTAATCTTTTAGAATTTATTTATTAA

Upstream 100 bases:

>100_bases
TGTTAAGAGAGCCAGAATTGTTGCTCTTTTACCCTTCGTAAATCCTGAAGGATAATTTCAAATTGAATATAGTTGGCACT
TTAATTAATATTTCAAATAT

Downstream 100 bases:

>100_bases
TAGGATAATAAATACAATAGGTTGTTATTAGTTTAAAAAATATCTGTTAGTATTAATAAAAAAGCTTTATGACTTTTGTC
ATTACTACACCTTTATACTA

Product: ribonuclease II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKDLTDLKTYIIDSDDPHEVDDAISLEIKEGNKKNLWIHISNPCKLFLHDSNVDLNARKRNSSLYLIDQYVPMLPNDILE
KANLAQNKVSETISAAIEFNDDGSINKYEITEAIIKPKYQLTYEDANEILEIEPKEEIELIEIKNLLKKSITFRKKQGAI
IFESPNNKIKLFEDKIILTKLEKTISQIIVAESMILMGYVTSLFLDKYNLAAAFRIQKINCNPSEILNRYIDSDIKYIIL
KQYMGRSYITIKPGIHESLGLKMYVQCTSPLRRYLDLIIQRQVYNKINNYEVLSKDSVSKIIDYSKNRQSENNNIFKNDK
FKYLRLFFNNEKKLFYNIIFVKWINHKKNIALVYFPDYSLEILITLFISIEIYSNKIYKVKYIINDSNLLEFIY

Sequences:

>Translated_394_residues
MKDLTDLKTYIIDSDDPHEVDDAISLEIKEGNKKNLWIHISNPCKLFLHDSNVDLNARKRNSSLYLIDQYVPMLPNDILE
KANLAQNKVSETISAAIEFNDDGSINKYEITEAIIKPKYQLTYEDANEILEIEPKEEIELIEIKNLLKKSITFRKKQGAI
IFESPNNKIKLFEDKIILTKLEKTISQIIVAESMILMGYVTSLFLDKYNLAAAFRIQKINCNPSEILNRYIDSDIKYIIL
KQYMGRSYITIKPGIHESLGLKMYVQCTSPLRRYLDLIIQRQVYNKINNYEVLSKDSVSKIIDYSKNRQSENNNIFKNDK
FKYLRLFFNNEKKLFYNIIFVKWINHKKNIALVYFPDYSLEILITLFISIEIYSNKIYKVKYIINDSNLLEFIY
>Mature_394_residues
MKDLTDLKTYIIDSDDPHEVDDAISLEIKEGNKKNLWIHISNPCKLFLHDSNVDLNARKRNSSLYLIDQYVPMLPNDILE
KANLAQNKVSETISAAIEFNDDGSINKYEITEAIIKPKYQLTYEDANEILEIEPKEEIELIEIKNLLKKSITFRKKQGAI
IFESPNNKIKLFEDKIILTKLEKTISQIIVAESMILMGYVTSLFLDKYNLAAAFRIQKINCNPSEILNRYIDSDIKYIIL
KQYMGRSYITIKPGIHESLGLKMYVQCTSPLRRYLDLIIQRQVYNKINNYEVLSKDSVSKIIDYSKNRQSENNNIFKNDK
FKYLRLFFNNEKKLFYNIIFVKWINHKKNIALVYFPDYSLEILITLFISIEIYSNKIYKVKYIINDSNLLEFIY

Specific function: 3'-5'Exoribonuclease That Participates In An Essential Cell Function. Acts Nonspecifically On Poly(A), Poly(U) And Ribosomal RNAs. Required For The Expression Of VIrulence Genes In Enteroinvasive Strains Of E.Coli. [C]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonuclease II (RNB) family [H]

Homologues:

Organism=Escherichia coli, GI87082383, Length=323, Percent_Identity=25.3869969040248, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787542, Length=320, Percent_Identity=24.0625, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323943, Length=332, Percent_Identity=29.8192771084337, Blast_Score=112, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001900
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00773 RNB [H]

EC number: 3.1.13.1

Molecular weight: Translated: 46351; Mature: 46351

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLTDLKTYIIDSDDPHEVDDAISLEIKEGNKKNLWIHISNPCKLFLHDSNVDLNARKR
CCCHHCCCEEEECCCCCCCCCCEEEEEEECCCCCEEEEEECCCEEEEEECCCCCEEEEEC
NSSLYLIDQYVPMLPNDILEKANLAQNKVSETISAAIEFNDDGSINKYEITEAIIKPKYQ
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEHHHHHHCCCEE
LTYEDANEILEIEPKEEIELIEIKNLLKKSITFRKKQGAIIFESPNNKIKLFEDKIILTK
EEECCCCCEEEECCCCCCHHHHHHHHHHHHHCEEECCCEEEEECCCCCEEEEECHHHHHH
LEKTISQIIVAESMILMGYVTSLFLDKYNLAAAFRIQKINCNPSEILNRYIDSDIKYIIL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCHHHHHHHHHCCCHHEEEE
KQYMGRSYITIKPGIHESLGLKMYVQCTSPLRRYLDLIIQRQVYNKINNYEVLSKDSVSK
HHHHCCEEEEECCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHH
IIDYSKNRQSENNNIFKNDKFKYLRLFFNNEKKLFYNIIFVKWINHKKNIALVYFPDYSL
HHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEEEEEEECCCCCEEEEEECCCCH
EILITLFISIEIYSNKIYKVKYIINDSNLLEFIY
HEEEEEEEEEEEECCEEEEEEEEECCCCEEEECC
>Mature Secondary Structure
MKDLTDLKTYIIDSDDPHEVDDAISLEIKEGNKKNLWIHISNPCKLFLHDSNVDLNARKR
CCCHHCCCEEEECCCCCCCCCCEEEEEEECCCCCEEEEEECCCEEEEEECCCCCEEEEEC
NSSLYLIDQYVPMLPNDILEKANLAQNKVSETISAAIEFNDDGSINKYEITEAIIKPKYQ
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEHHHHHHCCCEE
LTYEDANEILEIEPKEEIELIEIKNLLKKSITFRKKQGAIIFESPNNKIKLFEDKIILTK
EEECCCCCEEEECCCCCCHHHHHHHHHHHHHCEEECCCEEEEECCCCCEEEEECHHHHHH
LEKTISQIIVAESMILMGYVTSLFLDKYNLAAAFRIQKINCNPSEILNRYIDSDIKYIIL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCHHHHHHHHHCCCHHEEEE
KQYMGRSYITIKPGIHESLGLKMYVQCTSPLRRYLDLIIQRQVYNKINNYEVLSKDSVSK
HHHHCCEEEEECCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHH
IIDYSKNRQSENNNIFKNDKFKYLRLFFNNEKKLFYNIIFVKWINHKKNIALVYFPDYSL
HHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEEEEEEECCCCCEEEEEECCCCH
EILITLFISIEIYSNKIYKVKYIINDSNLLEFIY
HEEEEEEEEEEEECCEEEEEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]