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The map label for this gene is hisZ [H]

Identifier: 126696297

GI number: 126696297

Start: 825994

End: 827145

Strand: Reverse

Name: hisZ [H]

Synonym: P9301_09591

Alternate gene names: 126696297

Gene position: 827145-825994 (Counterclockwise)

Preceding gene: 126696298

Following gene: 126696296

Centisome position: 50.38

GC content: 25.95

Gene sequence:

>1152_bases
ATGACCGATATAAAGGAAATTAAATTAATCGATGTAAAAAATAACTCAAACATCATAAATAATTTAAATAGTATTTATAA
ACTATGGGGATATGAAGAGGTTTCACCCTCATTTATAAATACTTTAGAGACCATAAAAGGCCGTGGCGTTATTGATGAAA
ATCAGGTTGTAGGAATAGTAAGTAATAATTCATTATGTCTTAGGCCAGAAATGACTACATCGATTGTTAAATTGTCTTCC
ACTAGATTAATAAATAAGAAAAGACCTATAAGGTTATTCACCAATGGAATGGTTTTTGATAAAAAACAAAATAATAAAAA
TTCATTTAAGTTACAAGAAAAATTGCAGAGTGGAATTGAATTAATTGGATATGATACAAAATACCCAGAAATTGAAGTTA
TTAATATTTTGTTTGATTCAATCGATAATATTAATTTGAAGGATGGTTGTAATTTATTTCTACTAGTAAGCACAACAAAA
ATAATGGACTTGATCCTGAACAAATATAAGAATAATAATTTTGAAGAAATTAAGAAATGTCTGGTTAATTTTGATCAAGA
TAATTTATCTAAATTAAGAATAGATGAAAATGATAAATATATTCTTAAAGATCTTTTATTCACACGAGGAGAGCCCATTG
CAATATTAAAAAAATTAAAAACTATATTTGGTACTAGTAAAACATTAGATGACTTAAATTTTTTGTTTGAGACATTATCA
AATGTATCAAATAAATATGGTGTTAAATTACAACTTGATCCCACTTTTCAACCTCACTTGAATTTGTATGAAGGAATAGT
TTTTCAACTAATAGGGGATAATGGCAAAAATAAAAGCGTCATCGCAAAAGGCGGAAGATATGATGAGTTAGTGAGATCAT
TTAGTCCTAATGAGAAAATATTTAATGGGATTGGATTTACAATTTCAGTAGACATTTTAAGAAATTTAATTAAGGAAGAA
AAGACAGATAAAAAAAAGATTTTATTGATGTTTAAAGATTCTTATTTGTTAGAAAAAGGGATGAATGAACAAAAAGTACA
ACAGAAAAAAGGAAATATTGCTGTCTTACATTTAAATCCAATTAATGACTTGGCTAAAGCCAATCAAATTATGAAAGAAA
ATAATTGTAGTGAGATTTTGTGGGTAAAATAA

Upstream 100 bases:

>100_bases
AGCTTGTTCTCCCAGCCTTGAGAATGAATTAAAAAATGAACTAGATAAAGTTTCTCCATTAAAAAAAAATCTCTATACCT
AAAAATAGTTAAATATTAAA

Downstream 100 bases:

>100_bases
AGCCTTTTTAAAATTTATTTAACTTTTAAATTCATATATTGTTCGGACAATACTCCTAATTAAACTTGATTAACTAGTTT
TTACGAAATAAGATTTAATA

Product: ATP phosphoribosyltransferase regulatory subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MTDIKEIKLIDVKNNSNIINNLNSIYKLWGYEEVSPSFINTLETIKGRGVIDENQVVGIVSNNSLCLRPEMTTSIVKLSS
TRLINKKRPIRLFTNGMVFDKKQNNKNSFKLQEKLQSGIELIGYDTKYPEIEVINILFDSIDNINLKDGCNLFLLVSTTK
IMDLILNKYKNNNFEEIKKCLVNFDQDNLSKLRIDENDKYILKDLLFTRGEPIAILKKLKTIFGTSKTLDDLNFLFETLS
NVSNKYGVKLQLDPTFQPHLNLYEGIVFQLIGDNGKNKSVIAKGGRYDELVRSFSPNEKIFNGIGFTISVDILRNLIKEE
KTDKKKILLMFKDSYLLEKGMNEQKVQQKKGNIAVLHLNPINDLAKANQIMKENNCSEILWVK

Sequences:

>Translated_383_residues
MTDIKEIKLIDVKNNSNIINNLNSIYKLWGYEEVSPSFINTLETIKGRGVIDENQVVGIVSNNSLCLRPEMTTSIVKLSS
TRLINKKRPIRLFTNGMVFDKKQNNKNSFKLQEKLQSGIELIGYDTKYPEIEVINILFDSIDNINLKDGCNLFLLVSTTK
IMDLILNKYKNNNFEEIKKCLVNFDQDNLSKLRIDENDKYILKDLLFTRGEPIAILKKLKTIFGTSKTLDDLNFLFETLS
NVSNKYGVKLQLDPTFQPHLNLYEGIVFQLIGDNGKNKSVIAKGGRYDELVRSFSPNEKIFNGIGFTISVDILRNLIKEE
KTDKKKILLMFKDSYLLEKGMNEQKVQQKKGNIAVLHLNPINDLAKANQIMKENNCSEILWVK
>Mature_382_residues
TDIKEIKLIDVKNNSNIINNLNSIYKLWGYEEVSPSFINTLETIKGRGVIDENQVVGIVSNNSLCLRPEMTTSIVKLSST
RLINKKRPIRLFTNGMVFDKKQNNKNSFKLQEKLQSGIELIGYDTKYPEIEVINILFDSIDNINLKDGCNLFLLVSTTKI
MDLILNKYKNNNFEEIKKCLVNFDQDNLSKLRIDENDKYILKDLLFTRGEPIAILKKLKTIFGTSKTLDDLNFLFETLSN
VSNKYGVKLQLDPTFQPHLNLYEGIVFQLIGDNGKNKSVIAKGGRYDELVRSFSPNEKIFNGIGFTISVDILRNLIKEEK
TDKKKILLMFKDSYLLEKGMNEQKVQQKKGNIAVLHLNPINDLAKANQIMKENNCSEILWVK

Specific function: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine [H]

COG id: COG3705

COG function: function code E; ATP phosphoribosyltransferase involved in histidine biosynthesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004516 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 43945; Mature: 43813

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIKEIKLIDVKNNSNIINNLNSIYKLWGYEEVSPSFINTLETIKGRGVIDENQVVGIV
CCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEE
SNNSLCLRPEMTTSIVKLSSTRLINKKRPIRLFTNGMVFDKKQNNKNSFKLQEKLQSGIE
ECCCEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCEEEECCCCCCCHHHHHHHHHCCCE
LIGYDTKYPEIEVINILFDSIDNINLKDGCNLFLLVSTTKIMDLILNKYKNNNFEEIKKC
EEECCCCCCCCEEHHEEHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHH
LVNFDQDNLSKLRIDENDKYILKDLLFTRGEPIAILKKLKTIFGTSKTLDDLNFLFETLS
HHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
NVSNKYGVKLQLDPTFQPHLNLYEGIVFQLIGDNGKNKSVIAKGGRYDELVRSFSPNEKI
HCCHHCCEEEEECCCCCCCCHHHHCEEEEEECCCCCCCCEEECCCCHHHHHHHCCCCHHH
FNGIGFTISVDILRNLIKEEKTDKKKILLMFKDSYLLEKGMNEQKVQQKKGNIAVLHLNP
HCCCCCEEEHHHHHHHHHHCCCCCEEEEEEEECCHHHHCCCCHHHHHHHCCCEEEEEECC
INDLAKANQIMKENNCSEILWVK
HHHHHHHHHHHHCCCCCCEEEEC
>Mature Secondary Structure 
TDIKEIKLIDVKNNSNIINNLNSIYKLWGYEEVSPSFINTLETIKGRGVIDENQVVGIV
CCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEE
SNNSLCLRPEMTTSIVKLSSTRLINKKRPIRLFTNGMVFDKKQNNKNSFKLQEKLQSGIE
ECCCEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCEEEECCCCCCCHHHHHHHHHCCCE
LIGYDTKYPEIEVINILFDSIDNINLKDGCNLFLLVSTTKIMDLILNKYKNNNFEEIKKC
EEECCCCCCCCEEHHEEHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHH
LVNFDQDNLSKLRIDENDKYILKDLLFTRGEPIAILKKLKTIFGTSKTLDDLNFLFETLS
HHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
NVSNKYGVKLQLDPTFQPHLNLYEGIVFQLIGDNGKNKSVIAKGGRYDELVRSFSPNEKI
HCCHHCCEEEEECCCCCCCCHHHHCEEEEEECCCCCCCCEEECCCCHHHHHHHCCCCHHH
FNGIGFTISVDILRNLIKEEKTDKKKILLMFKDSYLLEKGMNEQKVQQKKGNIAVLHLNP
HCCCCCEEEHHHHHHHHHHCCCCCEEEEEEEECCHHHHCCCCHHHHHHHCCCEEEEEECC
INDLAKANQIMKENNCSEILWVK
HHHHHHHHHHHHCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]