Click here to switch to the map view.

The map label for this gene is metA [H]

Identifier: 126696008

GI number: 126696008

Start: 596514

End: 597464

Strand: Direct

Name: metA [H]

Synonym: P9301_06701

Alternate gene names: 126696008

Gene position: 596514-597464 (Clockwise)

Preceding gene: 126696007

Following gene: 126696011

Centisome position: 36.33

GC content: 35.12

Gene sequence:

>951_bases
ATGATATTAAAGCCGATTTCGAACAAGCACTTTCACAAATCACATAGGAAAGGAGATTTATTGGCTTTAATAATTCCTGG
TAATTATCACAAGATTAGTGATGTTGAGAAAAATCATATATCTTGGATCGAACCAGAATTGGCAAAAAGACAGGATATAC
GTCCTCTTAGGATTGGTATTTTGAATATTATGCCTCTTGGTAAGCAGTATGAATTTAACTTGCTACATCCACTTGGTTTA
TCTCCTCTTCAAATAGAGCCTGTTTGGATAAAGCTTAAAACTCACTCTTATAAGACATGGGATCTTAATCATCTAAATAA
TCTATACGTTACTTGGGAAGAAGCAAATAATCCAGAACCGTTAGACGGAATCATAATTACTGGGGCACCTATTGAGCACT
TAGCCTTTGAGGATGTTAATTATTGGGATGAATTTGTGAAAATTGTAAATGAAGCTAGAACTTCTTGTGCGAGTACTCTT
GGATTATGTTGGGCGGGCTTTGCTCTGGCTTATTTGGCAGGAGTTGATAAGCAAGTTTTTGATAGGAAATTATTTGGGGT
ATTCCCTTTAAAAAGTCTTGTTCCAGGACACCCTTTGATGGGTACACAAGATGATGAATTTATATGTCCTCAAAGTAGAT
TTGCAGGATTACCAGATTTAGAAATGGAGAAGGCCCAAAAAGAAGGGAAATTGAATTTGTTGGCTTATGGAGAAAACGTC
GGATATACAATATTTGAATCTATTGATCAAAAACAACTTATGCATTTAGGTCATCCTGAATATACGGTGCATAGAATTAT
TAGTGAAATTGAAAGAGACAAAGAAAAGGGAGATGTTCCTCCTCCTAAAAATTTTGATCCAAATAGTTCAAAAACCGCTT
GGAGATCGCATAGGAATTTGCTTTTTCAGCAATGGCTTTGGTTTTGTTATCAACAAGTTAGTCTTAATTAA

Upstream 100 bases:

>100_bases
CCGGCTTCAACTACTCATCAGCAATTATCTGAAGAAGAACAATTATCTGCAGGCGTTACCCCCACGATGGTAAGAGTTTC
TGTAGGAATTGAACATATTG

Downstream 100 bases:

>100_bases
CTTTCTTAATGAGCACTTTCAATACCGCCTAGTCTTTCAAATAAGTTAAGACTTTCTTTATTTAATCCTACAATTTCAAC
TTTAGAACCACCATTCTGGA

Product: putative homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MILKPISNKHFHKSHRKGDLLALIIPGNYHKISDVEKNHISWIEPELAKRQDIRPLRIGILNIMPLGKQYEFNLLHPLGL
SPLQIEPVWIKLKTHSYKTWDLNHLNNLYVTWEEANNPEPLDGIIITGAPIEHLAFEDVNYWDEFVKIVNEARTSCASTL
GLCWAGFALAYLAGVDKQVFDRKLFGVFPLKSLVPGHPLMGTQDDEFICPQSRFAGLPDLEMEKAQKEGKLNLLAYGENV
GYTIFESIDQKQLMHLGHPEYTVHRIISEIERDKEKGDVPPPKNFDPNSSKTAWRSHRNLLFQQWLWFCYQQVSLN

Sequences:

>Translated_316_residues
MILKPISNKHFHKSHRKGDLLALIIPGNYHKISDVEKNHISWIEPELAKRQDIRPLRIGILNIMPLGKQYEFNLLHPLGL
SPLQIEPVWIKLKTHSYKTWDLNHLNNLYVTWEEANNPEPLDGIIITGAPIEHLAFEDVNYWDEFVKIVNEARTSCASTL
GLCWAGFALAYLAGVDKQVFDRKLFGVFPLKSLVPGHPLMGTQDDEFICPQSRFAGLPDLEMEKAQKEGKLNLLAYGENV
GYTIFESIDQKQLMHLGHPEYTVHRIISEIERDKEKGDVPPPKNFDPNSSKTAWRSHRNLLFQQWLWFCYQQVSLN
>Mature_316_residues
MILKPISNKHFHKSHRKGDLLALIIPGNYHKISDVEKNHISWIEPELAKRQDIRPLRIGILNIMPLGKQYEFNLLHPLGL
SPLQIEPVWIKLKTHSYKTWDLNHLNNLYVTWEEANNPEPLDGIIITGAPIEHLAFEDVNYWDEFVKIVNEARTSCASTL
GLCWAGFALAYLAGVDKQVFDRKLFGVFPLKSLVPGHPLMGTQDDEFICPQSRFAGLPDLEMEKAQKEGKLNLLAYGENV
GYTIFESIDQKQLMHLGHPEYTVHRIISEIERDKEKGDVPPPKNFDPNSSKTAWRSHRNLLFQQWLWFCYQQVSLN

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=299, Percent_Identity=33.1103678929766, Blast_Score=155, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 36440; Mature: 36440

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKPISNKHFHKSHRKGDLLALIIPGNYHKISDVEKNHISWIEPELAKRQDIRPLRIGI
CCCCCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHEEEE
LNIMPLGKQYEFNLLHPLGLSPLQIEPVWIKLKTHSYKTWDLNHLNNLYVTWEEANNPEP
EEEECCCCCCCEEEECCCCCCCEEEEEEEEEEEECCEEEEECCCCCCEEEEEECCCCCCC
LDGIIITGAPIEHLAFEDVNYWDEFVKIVNEARTSCASTLGLCWAGFALAYLAGVDKQVF
CCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DRKLFGVFPLKSLVPGHPLMGTQDDEFICPQSRFAGLPDLEMEKAQKEGKLNLLAYGENV
HHHHHHCCCHHHHCCCCCCCCCCCCCEECCHHHCCCCCCHHHHHHHHCCCEEEEEECCCC
GYTIFESIDQKQLMHLGHPEYTVHRIISEIERDKEKGDVPPPKNFDPNSSKTAWRSHRNL
CCHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
LFQQWLWFCYQQVSLN
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MILKPISNKHFHKSHRKGDLLALIIPGNYHKISDVEKNHISWIEPELAKRQDIRPLRIGI
CCCCCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHEEEE
LNIMPLGKQYEFNLLHPLGLSPLQIEPVWIKLKTHSYKTWDLNHLNNLYVTWEEANNPEP
EEEECCCCCCCEEEECCCCCCCEEEEEEEEEEEECCEEEEECCCCCCEEEEEECCCCCCC
LDGIIITGAPIEHLAFEDVNYWDEFVKIVNEARTSCASTLGLCWAGFALAYLAGVDKQVF
CCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DRKLFGVFPLKSLVPGHPLMGTQDDEFICPQSRFAGLPDLEMEKAQKEGKLNLLAYGENV
HHHHHHCCCHHHHCCCCCCCCCCCCCEECCHHHCCCCCCHHHHHHHHCCCEEEEEECCCC
GYTIFESIDQKQLMHLGHPEYTVHRIISEIERDKEKGDVPPPKNFDPNSSKTAWRSHRNL
CCHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
LFQQWLWFCYQQVSLN
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA