| Definition | Prochlorococcus marinus str. MIT 9301, complete genome. |
|---|---|
| Accession | NC_009091 |
| Length | 1,641,879 |
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The map label for this gene is clpB2 [H]
Identifier: 126695565
GI number: 126695565
Start: 209214
End: 211970
Strand: Reverse
Name: clpB2 [H]
Synonym: P9301_02271
Alternate gene names: 126695565
Gene position: 211970-209214 (Counterclockwise)
Preceding gene: 126695567
Following gene: 126695564
Centisome position: 12.91
GC content: 30.58
Gene sequence:
>2757_bases ATGAGAGAAACCCTTACATCCAGTCCCGAATTATTTAGCGATATCAGTTGGAACCTTCTTTTATTAGGGGAAGAAACCGC AAAAAAATGGGATCATAGCGAATTTAATATTGAACACATAATTCATACATTGTTCTCATCAAGTGAATTCTTTGCTTTCA TTGAAAAATTATCAATCGACCAAGATACAGTTTTAGACATAACAGAAGATTTTTTAGAAGAGACACCAACAAATGAGTCA GATATTTTTACTATCGGAGAAGATTTAGAAATTTTATTAGATAACGCGAATCAGATTAAAACTCAATGGGGATCGAGATT AATAGAAATCCCTCATTTACTAATTGCTCTTGGAAGAGATTTAAGAATTGGGAATTATGTTTTTGAAGAAGGAAACCTTT CAATGGAAAAATTAGAGGAAGAATTAAAGTTTTACCCAAATATTAATCAATCAAAAGATTCTTTTAATTATGGGAATGTA ATTGAAATAAATAATCAATCTAATTTTGAATCAGATAAAGAAACTTTAGTTAAAGAAGAAAAATTGAAAAAAGCTATTGT TCCATTACCGAAAAGTGAACTTCAAATTGAAACCAAAAAACAAGTTGGAAAAGATGAAAATGCTCTTTCAATTTATGGAA AAGATTTAACAGAATCAGCTAAAAAAGGCTTAATGGATCCCATTTTAGGAAGAGAAAATGAGATCAATAATTTAATGAGG GTACTCTGCAGAAGAAACAAAAATAACCCTATACTCATTGGCAATCCTGGAGTTGGTAAAACCTCAATTGCAAAATTACT TGCTCAATTAATTGTAGACAAAAAAGTTCCTGATACTTTAAAGGACTTAAAAATTATTTCACTTGACTTAGGTGCATTAG TTTCTGGGACCAAATTTAGAGGTCAACTAGAAGAAAGACTAAGTTTAATAATACAGGAACTAAATAATCCAAACCAAGGA ATGATTCTATTTATTGATGAAATTCACTCAATATTAAGTTCTGACAGATCTTCTACCAACATCAGTAATGTTTTAAAACC TTTACTAGCTGAAGGAGAACTTAGATGTATCGGTACAACAACACCTGAGAAATTTCGTGAAACTATTGAAAAAGATCAGG CATTAAATAATTGCTTTCAAAAGATAGCTGTTAATGAACCTTCAGTAGAATTAAGCGCAAAAATACTACAAGGTATCAAA AAGAAATATGAATCACATCATGGCATAAAAATTTCTGAAGAGGCTGTAAACTATTCTGCAAAATTAGCCGATAGATACAT CAGCGATAAATGTCTCCCTGATAGCGCAATAGATTTAATTGATGAAGCAGCTGCACAGTTGAAAATCGAGTCTAATAATG TGCCTCAAATCATTCTTCAACAAGAAAACAAACTTAATACAATTGATGAAAAATTGAATAATTTGCAAGGAGAAAATATC GAAGCTCAAGAAAAACTATTGAATAATAGACAACAATCAGAGGCAAAATTGAACCTTCTTTTAGAAAATTGGAACAATTT ACGTGAAGAAATGGAGGAATTATCTATTTTAATGAAAGAAGAAGATAAGATAACCAAACAAATTAAAGATAAATCAAATC GAGAAATTGAAAATGATCTAGATTATTTAGAAAAGCTTGAAGAAGAGTTAAGTGAAATAGAGAATGACATACAAAAAGTT GAAGAGAACTTTAATAAAATAAAGAAAAATAGAAATTTCCCTTTTAAATATCAAGTTGAACCTGATGATATTGCTGATGT TGTCTCAAAAATTACAGGTATTCCAATTTCTAAAGTAGTTTCAAATGAGCGTAAGAAATTAGTCAATCTAGAGACAGAAC TAAGTGAAAAAGTTATTGGACAAGAAAAAGCTATAGAAGCTGTTTCTGCTGCAATTAGAAGAGCTCGCGTTGGCATGAAA AGTCCTAAAAGACCTATCGGATCTTTTTTATTTATGGGTCCTACAGGCGTTGGTAAAACAGAATTAGCAAAATCTCTTGC AACAGCTTTATTTGATGAAGAAGACGCACTTTTAAGATTAGACATGAGTGAATATATGGAGAAAAATGCTGTAGCAAGGC TTTTGGGAGCTCCTCCAGGTTATGTTGGTTATGAAGAGGGAGGTCAATTAACTGAAGCTGTAAGACGTAAACCCTATTCA GTAATACTTCTTGATGAGATAGAAAAAGCACATTCAGAAGTTTTTAATATCCTTTTACAAGTTTTAGATGAAGGAAGATT AACGGACTCTCAAGGAAGGACAGTAGACTTCAAAAATACCGTAATCATTATGACAAGCAACCTAGCTGGTAAATCTATAC TGGAATATTCACAAAAAATTTCTAGAAGTGATGGAAAGTTAGAAAAAGACCAACAAAACTTAGATGACTCCATTAGTAAT ACATTGTCTTCAATTTTTAGACCTGAATTTTTAAATAGAATTGATGAAGTGGTAAAGTTTAATCCATTATCTATTGATGA ACTTCAAAAAATAATAATTTTACAAACAGAAGATTTAAAAAACCTGCTACTTGAACAAAAAATAAATATCGCTATAGACA AAAAAGTTATTAATAAAATTGCAAATGATTCTTACGAACCTGAATATGGTGCTAGGCCACTTAGCAGGGAACTTAGAAGA CAAATAGAAAATCCCTTGGCTGCAAAACTTTTAGAGGAAAACTTCAAAAACAAAAAAAATATAATAATTAAACTTAACCC TGCTAAAAAAGATGAGATCATTTTCAAACCTAGCTGA
Upstream 100 bases:
>100_bases TCTTTGAAATTTCATCTTACAATTTGAAAATTATTGGATGATTATTAATGCATATCCTATTTAGAATATTAATTAATAAT CAACTGTAGTTTTATAGTTT
Downstream 100 bases:
>100_bases GGAGTAAATCAATAAGCTAAAATAAAAATTAAAGCGTAAAGCTTAATTTCAAAAAAAATTTTGTGACAAGTCCTACTACT AATAAAGAACCTGTTAAAAA
Product: putative ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 918; Mature: 918
Protein sequence:
>918_residues MRETLTSSPELFSDISWNLLLLGEETAKKWDHSEFNIEHIIHTLFSSSEFFAFIEKLSIDQDTVLDITEDFLEETPTNES DIFTIGEDLEILLDNANQIKTQWGSRLIEIPHLLIALGRDLRIGNYVFEEGNLSMEKLEEELKFYPNINQSKDSFNYGNV IEINNQSNFESDKETLVKEEKLKKAIVPLPKSELQIETKKQVGKDENALSIYGKDLTESAKKGLMDPILGRENEINNLMR VLCRRNKNNPILIGNPGVGKTSIAKLLAQLIVDKKVPDTLKDLKIISLDLGALVSGTKFRGQLEERLSLIIQELNNPNQG MILFIDEIHSILSSDRSSTNISNVLKPLLAEGELRCIGTTTPEKFRETIEKDQALNNCFQKIAVNEPSVELSAKILQGIK KKYESHHGIKISEEAVNYSAKLADRYISDKCLPDSAIDLIDEAAAQLKIESNNVPQIILQQENKLNTIDEKLNNLQGENI EAQEKLLNNRQQSEAKLNLLLENWNNLREEMEELSILMKEEDKITKQIKDKSNREIENDLDYLEKLEEELSEIENDIQKV EENFNKIKKNRNFPFKYQVEPDDIADVVSKITGIPISKVVSNERKKLVNLETELSEKVIGQEKAIEAVSAAIRRARVGMK SPKRPIGSFLFMGPTGVGKTELAKSLATALFDEEDALLRLDMSEYMEKNAVARLLGAPPGYVGYEEGGQLTEAVRRKPYS VILLDEIEKAHSEVFNILLQVLDEGRLTDSQGRTVDFKNTVIIMTSNLAGKSILEYSQKISRSDGKLEKDQQNLDDSISN TLSSIFRPEFLNRIDEVVKFNPLSIDELQKIIILQTEDLKNLLLEQKINIAIDKKVINKIANDSYEPEYGARPLSRELRR QIENPLAAKLLEENFKNKKNIIIKLNPAKKDEIIFKPS
Sequences:
>Translated_918_residues MRETLTSSPELFSDISWNLLLLGEETAKKWDHSEFNIEHIIHTLFSSSEFFAFIEKLSIDQDTVLDITEDFLEETPTNES DIFTIGEDLEILLDNANQIKTQWGSRLIEIPHLLIALGRDLRIGNYVFEEGNLSMEKLEEELKFYPNINQSKDSFNYGNV IEINNQSNFESDKETLVKEEKLKKAIVPLPKSELQIETKKQVGKDENALSIYGKDLTESAKKGLMDPILGRENEINNLMR VLCRRNKNNPILIGNPGVGKTSIAKLLAQLIVDKKVPDTLKDLKIISLDLGALVSGTKFRGQLEERLSLIIQELNNPNQG MILFIDEIHSILSSDRSSTNISNVLKPLLAEGELRCIGTTTPEKFRETIEKDQALNNCFQKIAVNEPSVELSAKILQGIK KKYESHHGIKISEEAVNYSAKLADRYISDKCLPDSAIDLIDEAAAQLKIESNNVPQIILQQENKLNTIDEKLNNLQGENI EAQEKLLNNRQQSEAKLNLLLENWNNLREEMEELSILMKEEDKITKQIKDKSNREIENDLDYLEKLEEELSEIENDIQKV EENFNKIKKNRNFPFKYQVEPDDIADVVSKITGIPISKVVSNERKKLVNLETELSEKVIGQEKAIEAVSAAIRRARVGMK SPKRPIGSFLFMGPTGVGKTELAKSLATALFDEEDALLRLDMSEYMEKNAVARLLGAPPGYVGYEEGGQLTEAVRRKPYS VILLDEIEKAHSEVFNILLQVLDEGRLTDSQGRTVDFKNTVIIMTSNLAGKSILEYSQKISRSDGKLEKDQQNLDDSISN TLSSIFRPEFLNRIDEVVKFNPLSIDELQKIIILQTEDLKNLLLEQKINIAIDKKVINKIANDSYEPEYGARPLSRELRR QIENPLAAKLLEENFKNKKNIIIKLNPAKKDEIIFKPS >Mature_918_residues MRETLTSSPELFSDISWNLLLLGEETAKKWDHSEFNIEHIIHTLFSSSEFFAFIEKLSIDQDTVLDITEDFLEETPTNES DIFTIGEDLEILLDNANQIKTQWGSRLIEIPHLLIALGRDLRIGNYVFEEGNLSMEKLEEELKFYPNINQSKDSFNYGNV IEINNQSNFESDKETLVKEEKLKKAIVPLPKSELQIETKKQVGKDENALSIYGKDLTESAKKGLMDPILGRENEINNLMR VLCRRNKNNPILIGNPGVGKTSIAKLLAQLIVDKKVPDTLKDLKIISLDLGALVSGTKFRGQLEERLSLIIQELNNPNQG MILFIDEIHSILSSDRSSTNISNVLKPLLAEGELRCIGTTTPEKFRETIEKDQALNNCFQKIAVNEPSVELSAKILQGIK KKYESHHGIKISEEAVNYSAKLADRYISDKCLPDSAIDLIDEAAAQLKIESNNVPQIILQQENKLNTIDEKLNNLQGENI EAQEKLLNNRQQSEAKLNLLLENWNNLREEMEELSILMKEEDKITKQIKDKSNREIENDLDYLEKLEEELSEIENDIQKV EENFNKIKKNRNFPFKYQVEPDDIADVVSKITGIPISKVVSNERKKLVNLETELSEKVIGQEKAIEAVSAAIRRARVGMK SPKRPIGSFLFMGPTGVGKTELAKSLATALFDEEDALLRLDMSEYMEKNAVARLLGAPPGYVGYEEGGQLTEAVRRKPYS VILLDEIEKAHSEVFNILLQVLDEGRLTDSQGRTVDFKNTVIIMTSNLAGKSILEYSQKISRSDGKLEKDQQNLDDSISN TLSSIFRPEFLNRIDEVVKFNPLSIDELQKIIILQTEDLKNLLLEQKINIAIDKKVINKIANDSYEPEYGARPLSRELRR QIENPLAAKLLEENFKNKKNIIIKLNPAKKDEIIFKPS
Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase
COG id: COG0542
COG function: function code O; ATPases with chaperone activity, ATP-binding subunit
Gene ontology:
Cell location: Cytoplasm (Probable) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the clpA/clpB family [H]
Homologues:
Organism=Homo sapiens, GI13540606, Length=301, Percent_Identity=39.8671096345515, Blast_Score=210, Evalue=4e-54, Organism=Escherichia coli, GI1788943, Length=714, Percent_Identity=45.2380952380952, Blast_Score=607, Evalue=1e-174, Organism=Escherichia coli, GI1787109, Length=340, Percent_Identity=42.9411764705882, Blast_Score=261, Evalue=1e-70, Organism=Saccharomyces cerevisiae, GI6320464, Length=700, Percent_Identity=42.8571428571429, Blast_Score=547, Evalue=1e-156, Organism=Saccharomyces cerevisiae, GI6323002, Length=930, Percent_Identity=34.1935483870968, Blast_Score=493, Evalue=1e-140,
Paralogues:
None
Copy number: 560 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR013093 - InterPro: IPR003959 - InterPro: IPR018368 - InterPro: IPR001270 - InterPro: IPR019489 - InterPro: IPR004176 - InterPro: IPR023150 [H]
Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]
EC number: NA
Molecular weight: Translated: 104241; Mature: 104241
Theoretical pI: Translated: 4.74; Mature: 4.74
Prosite motif: PS00871 CLPAB_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 1.7 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 1.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRETLTSSPELFSDISWNLLLLGEETAKKWDHSEFNIEHIIHTLFSSSEFFAFIEKLSID CCCCCCCCCHHHHCCCCCEEEEECHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCC QDTVLDITEDFLEETPTNESDIFTIGEDLEILLDNANQIKTQWGSRLIEIPHLLIALGRD CHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC LRIGNYVFEEGNLSMEKLEEELKFYPNINQSKDSFNYGNVIEINNQSNFESDKETLVKEE CEECCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHH KLKKAIVPLPKSELQIETKKQVGKDENALSIYGKDLTESAKKGLMDPILGRENEINNLMR HHHHHHCCCCCHHHEEEHHHHCCCCCCCEEEECCHHHHHHHHCCHHHHCCCCHHHHHHHH VLCRRNKNNPILIGNPGVGKTSIAKLLAQLIVDKKVPDTLKDLKIISLDLGALVSGTKFR HHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCEEEEEEHHHHHCCCHHH GQLEERLSLIIQELNNPNQGMILFIDEIHSILSSDRSSTNISNVLKPLLAEGELRCIGTT HHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECC TPEKFRETIEKDQALNNCFQKIAVNEPSVELSAKILQGIKKKYESHHGIKISEEAVNYSA CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHH KLADRYISDKCLPDSAIDLIDEAAAQLKIESNNVPQIILQQENKLNTIDEKLNNLQGENI HHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCCEEEEECCCCCHHHHHHHHCCCCCCC EAQEKLLNNRQQSEAKLNLLLENWNNLREEMEELSILMKEEDKITKQIKDKSNREIENDL HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH DYLEKLEEELSEIENDIQKVEENFNKIKKNRNFPFKYQVEPDDIADVVSKITGIPISKVV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCCHHHHH SNERKKLVNLETELSEKVIGQEKAIEAVSAAIRRARVGMKSPKRPIGSFLFMGPTGVGKT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHH ELAKSLATALFDEEDALLRLDMSEYMEKNAVARLLGAPPGYVGYEEGGQLTEAVRRKPYS HHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCE VILLDEIEKAHSEVFNILLQVLDEGRLTDSQGRTVDFKNTVIIMTSNLAGKSILEYSQKI EEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCCCHHHHHHHHHHH SRSDGKLEKDQQNLDDSISNTLSSIFRPEFLNRIDEVVKFNPLSIDELQKIIILQTEDLK HCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHEEECHHHH NLLLEQKINIAIDKKVINKIANDSYEPEYGARPLSRELRRQIENPLAAKLLEENFKNKKN HHHHHHHHCCEECHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCC IIIKLNPAKKDEIIFKPS EEEEECCCCCCCEEECCC >Mature Secondary Structure MRETLTSSPELFSDISWNLLLLGEETAKKWDHSEFNIEHIIHTLFSSSEFFAFIEKLSID CCCCCCCCCHHHHCCCCCEEEEECHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCC QDTVLDITEDFLEETPTNESDIFTIGEDLEILLDNANQIKTQWGSRLIEIPHLLIALGRD CHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC LRIGNYVFEEGNLSMEKLEEELKFYPNINQSKDSFNYGNVIEINNQSNFESDKETLVKEE CEECCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHH KLKKAIVPLPKSELQIETKKQVGKDENALSIYGKDLTESAKKGLMDPILGRENEINNLMR HHHHHHCCCCCHHHEEEHHHHCCCCCCCEEEECCHHHHHHHHCCHHHHCCCCHHHHHHHH VLCRRNKNNPILIGNPGVGKTSIAKLLAQLIVDKKVPDTLKDLKIISLDLGALVSGTKFR HHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCEEEEEEHHHHHCCCHHH GQLEERLSLIIQELNNPNQGMILFIDEIHSILSSDRSSTNISNVLKPLLAEGELRCIGTT HHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECC TPEKFRETIEKDQALNNCFQKIAVNEPSVELSAKILQGIKKKYESHHGIKISEEAVNYSA CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHH KLADRYISDKCLPDSAIDLIDEAAAQLKIESNNVPQIILQQENKLNTIDEKLNNLQGENI HHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCCEEEEECCCCCHHHHHHHHCCCCCCC EAQEKLLNNRQQSEAKLNLLLENWNNLREEMEELSILMKEEDKITKQIKDKSNREIENDL HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH DYLEKLEEELSEIENDIQKVEENFNKIKKNRNFPFKYQVEPDDIADVVSKITGIPISKVV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCCHHHHH SNERKKLVNLETELSEKVIGQEKAIEAVSAAIRRARVGMKSPKRPIGSFLFMGPTGVGKT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHH ELAKSLATALFDEEDALLRLDMSEYMEKNAVARLLGAPPGYVGYEEGGQLTEAVRRKPYS HHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCE VILLDEIEKAHSEVFNILLQVLDEGRLTDSQGRTVDFKNTVIIMTSNLAGKSILEYSQKI EEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCCCHHHHHHHHHHH SRSDGKLEKDQQNLDDSISNTLSSIFRPEFLNRIDEVVKFNPLSIDELQKIIILQTEDLK HCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHEEECHHHH NLLLEQKINIAIDKKVINKIANDSYEPEYGARPLSRELRRQIENPLAAKLLEENFKNKKN HHHHHHHHCCEECHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCC IIIKLNPAKKDEIIFKPS EEEEECCCCCCCEEECCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12917641 [H]