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The map label for this gene is ubiB [C]

Identifier: 126695567

GI number: 126695567

Start: 213525

End: 215192

Strand: Reverse

Name: ubiB [C]

Synonym: P9301_02291

Alternate gene names: 126695567

Gene position: 215192-213525 (Counterclockwise)

Preceding gene: 126695568

Following gene: 126695565

Centisome position: 13.11

GC content: 33.33

Gene sequence:

>1668_bases
ATGAGTTTTCAAATTCTTCATTATCGTTTAAAAAAATTGAAGAGGGCTTTTCTTATTTGGAAAACTCTTATTTCGCTTTT
AATAAATTTGTGGATAGATAATATTAGATTTACAATTTTCCAAATTAAAAGCAATGAAAAAAGTAGGGTCCAAATTAAAA
GAGCTAGGTGGTTTACTAATCAATTAATAAATCTTGGTTCAGCATTTATTAAAATTGGACAATTATTATCAGCGAGACCT
GATTTAATTCCTAATACCTGGATACAGGAATTGTCTAAATTGCAAGATCAAGTTCCTAATTTTTCATTTGAGCAAATTGA
AGAAACTATAAGAGAAGAACTAGGGTCCAAGTTTTATGAAATAGATCAAATAATAGCTGATCCGGTTGGATCAGCATCAC
TAGCTCAGGTTCATAGGGCGACTTTAAAAGATGGCAAGAAAGTAGTATTCAAAGTTCAAAGACCCAATTTAAAAGAATTG
TTTATTATCGATTTGGGCATAATGCAGCAGATAGCAGGATTGTTGCAAAAAAACAAGAACTGGAGTCGAGGTAGAAACTG
GGTTGAGATTGCTAAAGAGTGCAGAAAAGTTCTCATGAAGGAGCTTGATTTTAATTGTGAAGCACAATATGCAGCAAGAT
TTAGACAGCAATTTCTTGATGATGTAAATGTTGAAGTTCCTGAAGTGATTTGGGATATGAGCAGTGAAAAAGTGCTTTGC
TTAAGTTATCTTGAGGGAACGAAAATAAGCGATTTAGAAAAATTAAAATTACAAGAAATTGATTTGCCTAAAATTGCAGA
AATAGGGGCTATAAGCTATCTAAAACAATTAGTAAATTACGGTTTTTTCCATGCAGATCCTCATCCAGGGAATCTAGCAG
TTTCAAAAAAAGGTAAATTGATTTTTTATGATTTTGGAATGATGGGCAACATTTCAAATAATCTTCAAACAAGATTAGGG
GGGATGGTTAAGGCTGCCGCATTAAGAGACGCCTCATCACTTGTTAGCCAATTACAGCAAGCTGGGCTAATTTCAAAAGA
TATTGATGTTGGACCAGTCAGAAGATTAGTCAGACTGATGCTTAAAGAGGCCTTAACTCCCCCATTTAGCCCAAATATTA
TTGAAAAATTATCTGGAGATTTATACGAACTTGTTTATGAAACACCATTTCAACTACCAGTAGATTTAATCTTTGTGATG
AGAGCTTTATCAACTTTTGAAGGAGTTGGCAGAATGCTCGATCCAGGGTTTAACCTTGTATCAGTTACCAAGCCTTATTT
AATAGAACTTATGACTTCAAATAACCAAACTCCCAACGATTTAATTAACCAATTTGGAAGGCAAGTAGGTGAACTAGGAT
CTAAAGCTGTTGGAATTCCCAAAAGAATAGATGAAAGTTTAGAAAGATTAGAACAGGGCGATTTACAATTGCAAATAAGA
ATGGGAGAGTCTGATAGGCAATTCAAAAAAATGTTTACCGCTCAAAAAACTTTAGGCCATTCAATTCTTATAGGCAGCTT
ATCAATTGCATCTGCATTACTAGTAACCAATAAACAAAATAATTTTGCATTGTTGCCACTTCTTTTTGCAGTACCAATAA
GTATTGATTGGATAAAATGCCAATTAAGTATGAGAAAAGGCTCACGTTTAGAAAAACTAAAGCAATAA

Upstream 100 bases:

>100_bases
AAACTTATCAAGATTCGAAAATAAAAAAAGCTTTAAATGAAATTGAAGATATTAATGAACAAATTGATCTGTTTAATAAA
ACAATAAATAATCAAATTAA

Downstream 100 bases:

>100_bases
TAAACTATATATTTTTGGGACCTAAACCTAAAGCTCCAGCGAATCTTGCTTGATTTCCCAATTCCTCTTCAATTTTTAAA
AGCCTATTATATTTTGCAAT

Product: putative kinase

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MSFQILHYRLKKLKRAFLIWKTLISLLINLWIDNIRFTIFQIKSNEKSRVQIKRARWFTNQLINLGSAFIKIGQLLSARP
DLIPNTWIQELSKLQDQVPNFSFEQIEETIREELGSKFYEIDQIIADPVGSASLAQVHRATLKDGKKVVFKVQRPNLKEL
FIIDLGIMQQIAGLLQKNKNWSRGRNWVEIAKECRKVLMKELDFNCEAQYAARFRQQFLDDVNVEVPEVIWDMSSEKVLC
LSYLEGTKISDLEKLKLQEIDLPKIAEIGAISYLKQLVNYGFFHADPHPGNLAVSKKGKLIFYDFGMMGNISNNLQTRLG
GMVKAAALRDASSLVSQLQQAGLISKDIDVGPVRRLVRLMLKEALTPPFSPNIIEKLSGDLYELVYETPFQLPVDLIFVM
RALSTFEGVGRMLDPGFNLVSVTKPYLIELMTSNNQTPNDLINQFGRQVGELGSKAVGIPKRIDESLERLEQGDLQLQIR
MGESDRQFKKMFTAQKTLGHSILIGSLSIASALLVTNKQNNFALLPLLFAVPISIDWIKCQLSMRKGSRLEKLKQ

Sequences:

>Translated_555_residues
MSFQILHYRLKKLKRAFLIWKTLISLLINLWIDNIRFTIFQIKSNEKSRVQIKRARWFTNQLINLGSAFIKIGQLLSARP
DLIPNTWIQELSKLQDQVPNFSFEQIEETIREELGSKFYEIDQIIADPVGSASLAQVHRATLKDGKKVVFKVQRPNLKEL
FIIDLGIMQQIAGLLQKNKNWSRGRNWVEIAKECRKVLMKELDFNCEAQYAARFRQQFLDDVNVEVPEVIWDMSSEKVLC
LSYLEGTKISDLEKLKLQEIDLPKIAEIGAISYLKQLVNYGFFHADPHPGNLAVSKKGKLIFYDFGMMGNISNNLQTRLG
GMVKAAALRDASSLVSQLQQAGLISKDIDVGPVRRLVRLMLKEALTPPFSPNIIEKLSGDLYELVYETPFQLPVDLIFVM
RALSTFEGVGRMLDPGFNLVSVTKPYLIELMTSNNQTPNDLINQFGRQVGELGSKAVGIPKRIDESLERLEQGDLQLQIR
MGESDRQFKKMFTAQKTLGHSILIGSLSIASALLVTNKQNNFALLPLLFAVPISIDWIKCQLSMRKGSRLEKLKQ
>Mature_554_residues
SFQILHYRLKKLKRAFLIWKTLISLLINLWIDNIRFTIFQIKSNEKSRVQIKRARWFTNQLINLGSAFIKIGQLLSARPD
LIPNTWIQELSKLQDQVPNFSFEQIEETIREELGSKFYEIDQIIADPVGSASLAQVHRATLKDGKKVVFKVQRPNLKELF
IIDLGIMQQIAGLLQKNKNWSRGRNWVEIAKECRKVLMKELDFNCEAQYAARFRQQFLDDVNVEVPEVIWDMSSEKVLCL
SYLEGTKISDLEKLKLQEIDLPKIAEIGAISYLKQLVNYGFFHADPHPGNLAVSKKGKLIFYDFGMMGNISNNLQTRLGG
MVKAAALRDASSLVSQLQQAGLISKDIDVGPVRRLVRLMLKEALTPPFSPNIIEKLSGDLYELVYETPFQLPVDLIFVMR
ALSTFEGVGRMLDPGFNLVSVTKPYLIELMTSNNQTPNDLINQFGRQVGELGSKAVGIPKRIDESLERLEQGDLQLQIRM
GESDRQFKKMFTAQKTLGHSILIGSLSIASALLVTNKQNNFALLPLLFAVPISIDWIKCQLSMRKGSRLEKLKQ

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=267, Percent_Identity=32.2097378277154, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI41393593, Length=357, Percent_Identity=28.8515406162465, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI217035081, Length=201, Percent_Identity=32.3383084577114, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI34147522, Length=283, Percent_Identity=24.3816254416961, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI27363457, Length=275, Percent_Identity=24.3636363636364, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367309, Length=516, Percent_Identity=27.1317829457364, Blast_Score=163, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17559152, Length=258, Percent_Identity=31.3953488372093, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI32565180, Length=293, Percent_Identity=24.5733788395904, Blast_Score=82, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6323282, Length=251, Percent_Identity=31.4741035856574, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321319, Length=293, Percent_Identity=27.3037542662116, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6325148, Length=255, Percent_Identity=26.2745098039216, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24662575, Length=399, Percent_Identity=28.8220551378446, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI22024280, Length=310, Percent_Identity=30.6451612903226, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI18859849, Length=261, Percent_Identity=26.0536398467433, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 63200; Mature: 63069

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFQILHYRLKKLKRAFLIWKTLISLLINLWIDNIRFTIFQIKSNEKSRVQIKRARWFTN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHH
QLINLGSAFIKIGQLLSARPDLIPNTWIQELSKLQDQVPNFSFEQIEETIREELGSKFYE
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IDQIIADPVGSASLAQVHRATLKDGKKVVFKVQRPNLKELFIIDLGIMQQIAGLLQKNKN
HHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHCCCC
WSRGRNWVEIAKECRKVLMKELDFNCEAQYAARFRQQFLDDVNVEVPEVIWDMSSEKVLC
HHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEE
LSYLEGTKISDLEKLKLQEIDLPKIAEIGAISYLKQLVNYGFFHADPHPGNLAVSKKGKL
EEHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEECCCCE
IFYDFGMMGNISNNLQTRLGGMVKAAALRDASSLVSQLQQAGLISKDIDVGPVRRLVRLM
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LKEALTPPFSPNIIEKLSGDLYELVYETPFQLPVDLIFVMRALSTFEGVGRMLDPGFNLV
HHHHCCCCCCCHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
SVTKPYLIELMTSNNQTPNDLINQFGRQVGELGSKAVGIPKRIDESLERLEQGDLQLQIR
EECCHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEE
MGESDRQFKKMFTAQKTLGHSILIGSLSIASALLVTNKQNNFALLPLLFAVPISIDWIKC
ECCCHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCEEEEEE
QLSMRKGSRLEKLKQ
EEEHHCCCHHHHHCC
>Mature Secondary Structure 
SFQILHYRLKKLKRAFLIWKTLISLLINLWIDNIRFTIFQIKSNEKSRVQIKRARWFTN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHH
QLINLGSAFIKIGQLLSARPDLIPNTWIQELSKLQDQVPNFSFEQIEETIREELGSKFYE
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IDQIIADPVGSASLAQVHRATLKDGKKVVFKVQRPNLKELFIIDLGIMQQIAGLLQKNKN
HHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHCCCC
WSRGRNWVEIAKECRKVLMKELDFNCEAQYAARFRQQFLDDVNVEVPEVIWDMSSEKVLC
HHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEE
LSYLEGTKISDLEKLKLQEIDLPKIAEIGAISYLKQLVNYGFFHADPHPGNLAVSKKGKL
EEHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEECCCCE
IFYDFGMMGNISNNLQTRLGGMVKAAALRDASSLVSQLQQAGLISKDIDVGPVRRLVRLM
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LKEALTPPFSPNIIEKLSGDLYELVYETPFQLPVDLIFVMRALSTFEGVGRMLDPGFNLV
HHHHCCCCCCCHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
SVTKPYLIELMTSNNQTPNDLINQFGRQVGELGSKAVGIPKRIDESLERLEQGDLQLQIR
EECCHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEE
MGESDRQFKKMFTAQKTLGHSILIGSLSIASALLVTNKQNNFALLPLLFAVPISIDWIKC
ECCCHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCEEEEEE
QLSMRKGSRLEKLKQ
EEEHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]