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The map label for this gene is menC [H]

Identifier: 126695533

GI number: 126695533

Start: 179638

End: 180603

Strand: Reverse

Name: menC [H]

Synonym: P9301_01951

Alternate gene names: 126695533

Gene position: 180603-179638 (Counterclockwise)

Preceding gene: 126695534

Following gene: 126695532

Centisome position: 11.0

GC content: 28.67

Gene sequence:

>966_bases
ATGAACTTAATATTTCAAAAAAAATCTTATAGCTTTAAGTTATCGGCCAAAGTAGAAAATTCTAAAACCAATTACCATAC
AAAATCGGGTTGGATAATTAAATTAATAAGTAATGATAAAAAAATAGGGTTTGGAGAAGTTTCACCGCTACAAAAAAAAG
ACTTAAAAAAGTGTGCGAAACAACTAGATATGATCCCTGAGTATATAGAGGAATTTAATTTATCTGAGCAAATAAATATT
TTTCACCCATGCATTCAATCTGCAATAAATTCTGCATTAGCTGAGATTAATGGAAAAATAATTTTTAAAGAAAACTACTA
CTTTGATGAAATTGGTAAAACAGCCATATTGTTAAATCATGAAAATGTAGTTTCAGATCTAAATGATATTAAAAAAAGAC
ATTGTGATATTGGAAAATCATTAACCTTAAAATGGAAAGTAGCACTAAAAAATAACCATGAGGAAGAAGCAAAATTAGAA
GAAATTTTAAGCAAAATAGGTAATAATATTAAGTTAAGAATAGATGCTAATGGTTCTTGGGGAAGAGAGATAGCTAATAG
ATGGGCTGATATTTTAAAAGATAATAAAAATATAGATTGGTTAGAACAACCTCTCTGTGTTGATGATATTGATGGACTGA
CAGAACTAAACAAAAAAATTCCAATAGCTTTAGACGAATCACTTTTAAAATTTCCAACTTTGATTGATGAGTGGAAGGGT
TGGCAAATTAGAAGGCCTTCTCAAGAAAATAATCCAGTTAAGCTTTTAAGAGAATTAGAAAATAAAAAAGCTTTAATATC
TATAAGTACCTCATTTGAAACTGGAATAGGAAAGAGATGGCTCCATCATTTATCTTCTCTACAATTACAAGGACCAACAC
CAAAAGTTCCTGGTTTAGCAATGAATAAATTCCCTAATTCGTTTCTATTTTTAAATGAAGCAAAAACGATATGGGATCAA
CTATGA

Upstream 100 bases:

>100_bases
CTTCTGCAATAAAAAATTGCAAATTCATCGCAATAAAGTTTCAAACGCTTAATGGAATTGGTTTAATCACAGGATTAATA
TTTAATTACTTGCTAAATAA

Downstream 100 bases:

>100_bases
AAAATAAAATTCATACTATTGAAGTTGAAAATAACGAAACTCAATCTGTAGAAAAAATTATTGAAAAAATTAGAGATAAT
AAAATTATTTATGTAAAAAA

Product: putative O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MNLIFQKKSYSFKLSAKVENSKTNYHTKSGWIIKLISNDKKIGFGEVSPLQKKDLKKCAKQLDMIPEYIEEFNLSEQINI
FHPCIQSAINSALAEINGKIIFKENYYFDEIGKTAILLNHENVVSDLNDIKKRHCDIGKSLTLKWKVALKNNHEEEAKLE
EILSKIGNNIKLRIDANGSWGREIANRWADILKDNKNIDWLEQPLCVDDIDGLTELNKKIPIALDESLLKFPTLIDEWKG
WQIRRPSQENNPVKLLRELENKKALISISTSFETGIGKRWLHHLSSLQLQGPTPKVPGLAMNKFPNSFLFLNEAKTIWDQ
L

Sequences:

>Translated_321_residues
MNLIFQKKSYSFKLSAKVENSKTNYHTKSGWIIKLISNDKKIGFGEVSPLQKKDLKKCAKQLDMIPEYIEEFNLSEQINI
FHPCIQSAINSALAEINGKIIFKENYYFDEIGKTAILLNHENVVSDLNDIKKRHCDIGKSLTLKWKVALKNNHEEEAKLE
EILSKIGNNIKLRIDANGSWGREIANRWADILKDNKNIDWLEQPLCVDDIDGLTELNKKIPIALDESLLKFPTLIDEWKG
WQIRRPSQENNPVKLLRELENKKALISISTSFETGIGKRWLHHLSSLQLQGPTPKVPGLAMNKFPNSFLFLNEAKTIWDQ
L
>Mature_321_residues
MNLIFQKKSYSFKLSAKVENSKTNYHTKSGWIIKLISNDKKIGFGEVSPLQKKDLKKCAKQLDMIPEYIEEFNLSEQINI
FHPCIQSAINSALAEINGKIIFKENYYFDEIGKTAILLNHENVVSDLNDIKKRHCDIGKSLTLKWKVALKNNHEEEAKLE
EILSKIGNNIKLRIDANGSWGREIANRWADILKDNKNIDWLEQPLCVDDIDGLTELNKKIPIALDESLLKFPTLIDEWKG
WQIRRPSQENNPVKLLRELENKKALISISTSFETGIGKRWLHHLSSLQLQGPTPKVPGLAMNKFPNSFLFLNEAKTIWDQ
L

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR001354
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 36920; Mature: 36920

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIFQKKSYSFKLSAKVENSKTNYHTKSGWIIKLISNDKKIGFGEVSPLQKKDLKKCAK
CCCEEECCCCCEEEEEEEECCCCCEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
QLDMIPEYIEEFNLSEQINIFHPCIQSAINSALAEINGKIIFKENYYFDEIGKTAILLNH
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCEEEEEEC
ENVVSDLNDIKKRHCDIGKSLTLKWKVALKNNHEEEAKLEEILSKIGNNIKLRIDANGSW
HHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCH
GREIANRWADILKDNKNIDWLEQPLCVDDIDGLTELNKKIPIALDESLLKFPTLIDEWKG
HHHHHHHHHHHHHCCCCCCHHHCCCCHHCCCCHHHHCCCCCEEEHHHHHHHHHHHHHCCC
WQIRRPSQENNPVKLLRELENKKALISISTSFETGIGKRWLHHLSSLQLQGPTPKVPGLA
CEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCEEECCCCCCCCCCC
MNKFPNSFLFLNEAKTIWDQL
HHHCCCCEEEEEHHHHHHHCC
>Mature Secondary Structure
MNLIFQKKSYSFKLSAKVENSKTNYHTKSGWIIKLISNDKKIGFGEVSPLQKKDLKKCAK
CCCEEECCCCCEEEEEEEECCCCCEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
QLDMIPEYIEEFNLSEQINIFHPCIQSAINSALAEINGKIIFKENYYFDEIGKTAILLNH
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCEEEEEEC
ENVVSDLNDIKKRHCDIGKSLTLKWKVALKNNHEEEAKLEEILSKIGNNIKLRIDANGSW
HHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCH
GREIANRWADILKDNKNIDWLEQPLCVDDIDGLTELNKKIPIALDESLLKFPTLIDEWKG
HHHHHHHHHHHHHCCCCCCHHHCCCCHHCCCCHHHHCCCCCEEEHHHHHHHHHHHHHCCC
WQIRRPSQENNPVKLLRELENKKALISISTSFETGIGKRWLHHLSSLQLQGPTPKVPGLA
CEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCEEECCCCCCCCCCC
MNKFPNSFLFLNEAKTIWDQL
HHHCCCCEEEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]