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The map label for this gene is coaE [H]

Identifier: 126695390

GI number: 126695390

Start: 57055

End: 57672

Strand: Reverse

Name: coaE [H]

Synonym: P9301_00521

Alternate gene names: 126695390

Gene position: 57672-57055 (Counterclockwise)

Preceding gene: 126695392

Following gene: 126695388

Centisome position: 3.51

GC content: 26.05

Gene sequence:

>618_bases
ATGGATATTCTTCAAAAATCAAAAAACAACCAAAGAAGGATTGGTTTAACAGGAGGTATTGCAAGTGGAAAGACAACCAT
AACCAATTACATTAAAAAACATAAAAACATACCAATATTAGATGCAGATCATTTTTCAAGAGAATTAATTAAACCAAACA
CATATGGATATAAGAAAATTTTAGATTATTTTGGAAATAAAATTATTGATAATAAGAGCAATTCAGAAAGAGAAATAAAC
AGAAAACTTTTAAGGAACATTATTTTTAAACACTCAGCAAGCAAGGAATGGATTGAAAAACTACTTCACCCCTTGATTAA
AGAAAGAATGATAGAAGAATGCAGTCAATACAGAAATAATCAAACTATAGTATTGGTTATTCCATTATTGTTTGAAGCAA
AATTTGAAGATATTTGCACTGAAATATGGTTAGTTAAATGTTCTAAAGAACTACAAAAAAACAGACTCATCACAAGAGAT
AAAATTAGTGAAAAAGAAGCATATGAATTGATAAATTTTCAATTAAGTTTTGAAGAAAAAAGAAAATTTTCAGATATTAT
TTTAGATAATTCGGATGATCAAAATAAATGGGTCAATACGATAAAGGAGCTTCTTTAA

Upstream 100 bases:

>100_bases
CCAATTGGAATCTAACTGGCTCAAATTTTTTGGTATTTTAATTCATACTAACTACTCTTTAATACTAAAGAAACTAAGTA
ATTAGATTATTATTAATTAT

Downstream 100 bases:

>100_bases
ACTTTAATTATTTAATTTTTCCATAAGAAGTTTATTTGCAAGTTTAGGGTCAGCTTTACCTTTTGTTCTTTTCATAAGTT
GACCAACAAAAAAACCAAGT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MDILQKSKNNQRRIGLTGGIASGKTTITNYIKKHKNIPILDADHFSRELIKPNTYGYKKILDYFGNKIIDNKSNSEREIN
RKLLRNIIFKHSASKEWIEKLLHPLIKERMIEECSQYRNNQTIVLVIPLLFEAKFEDICTEIWLVKCSKELQKNRLITRD
KISEKEAYELINFQLSFEEKRKFSDIILDNSDDQNKWVNTIKELL

Sequences:

>Translated_205_residues
MDILQKSKNNQRRIGLTGGIASGKTTITNYIKKHKNIPILDADHFSRELIKPNTYGYKKILDYFGNKIIDNKSNSEREIN
RKLLRNIIFKHSASKEWIEKLLHPLIKERMIEECSQYRNNQTIVLVIPLLFEAKFEDICTEIWLVKCSKELQKNRLITRD
KISEKEAYELINFQLSFEEKRKFSDIILDNSDDQNKWVNTIKELL
>Mature_205_residues
MDILQKSKNNQRRIGLTGGIASGKTTITNYIKKHKNIPILDADHFSRELIKPNTYGYKKILDYFGNKIIDNKSNSEREIN
RKLLRNIIFKHSASKEWIEKLLHPLIKERMIEECSQYRNNQTIVLVIPLLFEAKFEDICTEIWLVKCSKELQKNRLITRD
KISEKEAYELINFQLSFEEKRKFSDIILDNSDDQNKWVNTIKELL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=195, Percent_Identity=29.7435897435897, Blast_Score=103, Evalue=8e-23,
Organism=Homo sapiens, GI191252795, Length=195, Percent_Identity=29.7435897435897, Blast_Score=103, Evalue=8e-23,
Organism=Homo sapiens, GI110227607, Length=179, Percent_Identity=25.6983240223464, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI110227605, Length=179, Percent_Identity=25.6983240223464, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI110227603, Length=179, Percent_Identity=25.6983240223464, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI110227601, Length=179, Percent_Identity=25.6983240223464, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI205277394, Length=179, Percent_Identity=25.6983240223464, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786292, Length=191, Percent_Identity=27.7486910994764, Blast_Score=94, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17554944, Length=179, Percent_Identity=30.7262569832402, Blast_Score=104, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI25143409, Length=175, Percent_Identity=25.1428571428571, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320402, Length=180, Percent_Identity=36.6666666666667, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24644728, Length=180, Percent_Identity=31.6666666666667, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24658602, Length=185, Percent_Identity=27.5675675675676, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 24287; Mature: 24287

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILQKSKNNQRRIGLTGGIASGKTTITNYIKKHKNIPILDADHFSRELIKPNTYGYKKI
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEECHHHHHHHCCCCCCCHHHH
LDYFGNKIIDNKSNSEREINRKLLRNIIFKHSASKEWIEKLLHPLIKERMIEECSQYRNN
HHHHCCHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
QTIVLVIPLLFEAKFEDICTEIWLVKCSKELQKNRLITRDKISEKEAYELINFQLSFEEK
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHEECHHHH
RKFSDIILDNSDDQNKWVNTIKELL
HHHHHHHCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MDILQKSKNNQRRIGLTGGIASGKTTITNYIKKHKNIPILDADHFSRELIKPNTYGYKKI
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEECHHHHHHHCCCCCCCHHHH
LDYFGNKIIDNKSNSEREINRKLLRNIIFKHSASKEWIEKLLHPLIKERMIEECSQYRNN
HHHHCCHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
QTIVLVIPLLFEAKFEDICTEIWLVKCSKELQKNRLITRDKISEKEAYELINFQLSFEEK
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHEECHHHH
RKFSDIILDNSDDQNKWVNTIKELL
HHHHHHHCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA