Click here to switch to the map view.

The map label for this gene is murB [H]

Identifier: 126695358

GI number: 126695358

Start: 21661

End: 22554

Strand: Reverse

Name: murB [H]

Synonym: P9301_00201

Alternate gene names: 126695358

Gene position: 22554-21661 (Counterclockwise)

Preceding gene: 126695359

Following gene: 126695357

Centisome position: 1.37

GC content: 28.3

Gene sequence:

>894_bases
ATGAAAAAAACAATTCTTTCTGAAAGCTGTAATTTAAGTAATTATACGACTATAAAAGTGGGAGGAATAGCTGAATATTT
TGCTGAGCCAGTAAGCATTGAAGAATTTTCATATCTAATAAAATGGGCCAATTTAAACAAACAAAGATGTCAAATAATTG
GCGCAGGTTCAAATCTTTTAATAAATAATATTTTCATAAAAGGCTTAGTTTTATGTACAAAAAAATTAAAATCATTAAAG
ATAGAGCCATATTCAGGAATTGTTGAAGCTGAAGCAGGTGTAATGCTCCCAACATTATCTAATTCTCTTGCTAAAAATGG
ATTACAAGGAGGGGAATGGGCTGTCGGAATTCCAGGAACATTAGGAGGAGCAATTTATATGAATGCAGGCACAGGAAATT
TATCACTAGCAAAAAATCTTATTTCCGTAAAAGTTATAAATAATAAAACTCATGAACAACTTGAAATTGAAAAAAAAGAT
ATAAACTTTGAGTATAGATTTAGCTCTTTTCAAAAAAATGATTTAACAATTATTAGTGCAAGACTACATTTTGAGCCTAA
TGGAAATCTAGAACAACTAATTCAAACAACCAAAAATAACCTTAAATTAAAAACAGAAACACAACCATATCATCAACCAA
GCTTTGGTAGTGTTTTTAAAAATCCTGAAAATCATTATGCTGCTAAATTAATTGATGAAATGGGTTTAAAAGGATTTAAA
ATTGGCGGTGCTGAAATTTCTACAATACATTCAAATTTTATAATTAATACTTCTTCAGCAAGTTCAAAAGATATTTTTGA
ATTAATAACAGTAATTCAACAAAAAGTACTACAAAACAAAGGAATTTATTTGCAACCGGAAGTAAGAATGATTGGTTTTG
ACTATCCTAATTAA

Upstream 100 bases:

>100_bases
ATTAACTCAAAAAGGGGATTTAATTTTGAATATGGGAGCTGGTGATTGTCATAATTTCTGGTCAATTTTAAATAAAAATA
ATTAAATGGATAAATAATTT

Downstream 100 bases:

>100_bases
AGAAACTTTTTTACAAAATGGCGGGTTTTGGACTTCCAAACTTTGGACAACTTACAGAAGCTTTTAAAAAAGCTAAACAA
ATTCAGCAAGATGCTCAAAA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKKTILSESCNLSNYTTIKVGGIAEYFAEPVSIEEFSYLIKWANLNKQRCQIIGAGSNLLINNIFIKGLVLCTKKLKSLK
IEPYSGIVEAEAGVMLPTLSNSLAKNGLQGGEWAVGIPGTLGGAIYMNAGTGNLSLAKNLISVKVINNKTHEQLEIEKKD
INFEYRFSSFQKNDLTIISARLHFEPNGNLEQLIQTTKNNLKLKTETQPYHQPSFGSVFKNPENHYAAKLIDEMGLKGFK
IGGAEISTIHSNFIINTSSASSKDIFELITVIQQKVLQNKGIYLQPEVRMIGFDYPN

Sequences:

>Translated_297_residues
MKKTILSESCNLSNYTTIKVGGIAEYFAEPVSIEEFSYLIKWANLNKQRCQIIGAGSNLLINNIFIKGLVLCTKKLKSLK
IEPYSGIVEAEAGVMLPTLSNSLAKNGLQGGEWAVGIPGTLGGAIYMNAGTGNLSLAKNLISVKVINNKTHEQLEIEKKD
INFEYRFSSFQKNDLTIISARLHFEPNGNLEQLIQTTKNNLKLKTETQPYHQPSFGSVFKNPENHYAAKLIDEMGLKGFK
IGGAEISTIHSNFIINTSSASSKDIFELITVIQQKVLQNKGIYLQPEVRMIGFDYPN
>Mature_297_residues
MKKTILSESCNLSNYTTIKVGGIAEYFAEPVSIEEFSYLIKWANLNKQRCQIIGAGSNLLINNIFIKGLVLCTKKLKSLK
IEPYSGIVEAEAGVMLPTLSNSLAKNGLQGGEWAVGIPGTLGGAIYMNAGTGNLSLAKNLISVKVINNKTHEQLEIEKKD
INFEYRFSSFQKNDLTIISARLHFEPNGNLEQLIQTTKNNLKLKTETQPYHQPSFGSVFKNPENHYAAKLIDEMGLKGFK
IGGAEISTIHSNFIINTSSASSKDIFELITVIQQKVLQNKGIYLQPEVRMIGFDYPN

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 32895; Mature: 32895

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTILSESCNLSNYTTIKVGGIAEYFAEPVSIEEFSYLIKWANLNKQRCQIIGAGSNLL
CCCCCCCCCCCCCCEEEEEECCHHHHHCCCCCHHHHHHEEEECCCCCCCEEEEECCCCEE
INNIFIKGLVLCTKKLKSLKIEPYSGIVEAEAGVMLPTLSNSLAKNGLQGGEWAVGIPGT
EHHHHHHHHHHHHHHHHHEECCCCCCEEECCCCEECHHHHHHHHHCCCCCCCEEEECCCC
LGGAIYMNAGTGNLSLAKNLISVKVINNKTHEQLEIEKKDINFEYRFSSFQKNDLTIISA
CCCEEEEECCCCCHHHHHCEEEEEEECCCCCCEEEEEHHCCCEEEEECCCCCCCEEEEEE
RLHFEPNGNLEQLIQTTKNNLKLKTETQPYHQPSFGSVFKNPENHYAAKLIDEMGLKGFK
EEEECCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCEEE
IGGAEISTIHSNFIINTSSASSKDIFELITVIQQKVLQNKGIYLQPEVRMIGFDYPN
ECCCEEEEEECEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCC
>Mature Secondary Structure
MKKTILSESCNLSNYTTIKVGGIAEYFAEPVSIEEFSYLIKWANLNKQRCQIIGAGSNLL
CCCCCCCCCCCCCCEEEEEECCHHHHHCCCCCHHHHHHEEEECCCCCCCEEEEECCCCEE
INNIFIKGLVLCTKKLKSLKIEPYSGIVEAEAGVMLPTLSNSLAKNGLQGGEWAVGIPGT
EHHHHHHHHHHHHHHHHHEECCCCCCEEECCCCEECHHHHHHHHHCCCCCCCEEEECCCC
LGGAIYMNAGTGNLSLAKNLISVKVINNKTHEQLEIEKKDINFEYRFSSFQKNDLTIISA
CCCEEEEECCCCCHHHHHCEEEEEEECCCCCCEEEEEHHCCCEEEEECCCCCCCEEEEEE
RLHFEPNGNLEQLIQTTKNNLKLKTETQPYHQPSFGSVFKNPENHYAAKLIDEMGLKGFK
EEEECCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCEEE
IGGAEISTIHSNFIINTSSASSKDIFELITVIQQKVLQNKGIYLQPEVRMIGFDYPN
ECCCEEEEEECEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]