| Definition | Prochlorococcus marinus str. MIT 9301, complete genome. |
|---|---|
| Accession | NC_009091 |
| Length | 1,641,879 |
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The map label for this gene is murC [H]
Identifier: 126695359
GI number: 126695359
Start: 22570
End: 23916
Strand: Reverse
Name: murC [H]
Synonym: P9301_00211
Alternate gene names: 126695359
Gene position: 23916-22570 (Counterclockwise)
Preceding gene: 126695361
Following gene: 126695358
Centisome position: 1.46
GC content: 27.91
Gene sequence:
>1347_bases ATGTCAGCATTAGCAATAGGTTTACTTAAAAAAGGTTATTCAGTTTCAGGATCTGATTTAGTTAAAAATGATGAAACCAA TAAATTAGAGAAATTAGGTGCAGTAATCTTTAATTCTCAAGTACGACAAAATATTGAATTTATTATTTCAAAATTTACCA ACAAATTGATTTATTTTGTTGTAAGCTCCGCGATCAAGCCAGAAAATGAAGAATTTTCGTACTGCAGAGAAAATAATTTA TCAATAAAACATCGTTCAGAGATACTTGCAATGCTAATGCGCACTTACACTGCATTGGCGGTAGCAGGCAGCCACGGAAA AACATCAACCAGTACATTTCTTTCAACAATACTTGAGTTATGTACACGTAATTCGTCTTCAATAACTGGAGGAATAATTC CTATTTACAACTCTAATTGTCATTTAGATAATACAAAATACTTAGTAGCTGAAGTTGATGAATCTGATGGAACAATTAAC AAATATAAGTCTGATATCGGAATAATTAATAACATTGATTTTGATCATTGCGATCACTTTTCTAATTTAAATGAAGTAAT CTCTACTTTTAAAAGTTTCGCTAAAAACTCTAAAAAATTACTACTTAATTTTGATTGTGAAACGTCAAGAAATAATTTTT ATTCTAATTGGAAGTGGTCAAACAGTACTGCTAAAAACGTTACTTATGCAATAATTCCGATTGAGATTAATTCAAAGTAT ACAATTGGGAAATATTATGAAAATGGAAATTTTATTAGTAGTTTAAATATCCCAATTCCAGGTTTACACAATCTATCAAA TATCACCGCAGCAATAGCTGCTTCAAGAATGATAGGAGTAGATTTTATAGAAATTAAAAAAAATATAAAATATCTAAAAC TGCCAAAAAAAAGATTTGAATTTAGAGGCCAATTAGATGAAAGAAGTTTATATGATGATTATGCACATCACCCAAACGAA ATAAAAGAAACGATTAAATTAGGAAGATTATTGATTCAACAAAACCATAATAAAGAATGTCAAAAAAGTAGATTAATAGC TATATTTCAACCTCATAGATACTCTCGAGTAAAACAATTTACGAAAGAATTCGCTGAAGAATTATCAAAAGCAGATGTTA TTTATGTAACCAGTATTTATGGAGCAGGGGAAGGAAACGAAGATAGAATAACTTCGAAAATTATCACTGATCTGATTTAT AAAAAAAATAAAAATGTTAGTTACATAAATAATTATTATGAAGTTACGAAGAATTTTTACGAATTAACTCAAAAAGGGGA TTTAATTTTGAATATGGGAGCTGGTGATTGTCATAATTTCTGGTCAATTTTAAATAAAAATAATTAA
Upstream 100 bases:
>100_bases TATACCTAGAAGTTATTTTGATTTAAGTAAAAGATAAACATTGGATAAAGAATTACTATTGAAAGGTCATTTTCATTTTA TTGGGATTGGGGGTATTGGG
Downstream 100 bases:
>100_bases ATGGATAAATAATTTATGAAAAAAACAATTCTTTCTGAAAGCTGTAATTTAAGTAATTATACGACTATAAAAGTGGGAGG AATAGCTGAATATTTTGCTG
Product: UDP-N-acetylmuramate-alanine ligase
Products: NA
Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]
Number of amino acids: Translated: 448; Mature: 447
Protein sequence:
>448_residues MSALAIGLLKKGYSVSGSDLVKNDETNKLEKLGAVIFNSQVRQNIEFIISKFTNKLIYFVVSSAIKPENEEFSYCRENNL SIKHRSEILAMLMRTYTALAVAGSHGKTSTSTFLSTILELCTRNSSSITGGIIPIYNSNCHLDNTKYLVAEVDESDGTIN KYKSDIGIINNIDFDHCDHFSNLNEVISTFKSFAKNSKKLLLNFDCETSRNNFYSNWKWSNSTAKNVTYAIIPIEINSKY TIGKYYENGNFISSLNIPIPGLHNLSNITAAIAASRMIGVDFIEIKKNIKYLKLPKKRFEFRGQLDERSLYDDYAHHPNE IKETIKLGRLLIQQNHNKECQKSRLIAIFQPHRYSRVKQFTKEFAEELSKADVIYVTSIYGAGEGNEDRITSKIITDLIY KKNKNVSYINNYYEVTKNFYELTQKGDLILNMGAGDCHNFWSILNKNN
Sequences:
>Translated_448_residues MSALAIGLLKKGYSVSGSDLVKNDETNKLEKLGAVIFNSQVRQNIEFIISKFTNKLIYFVVSSAIKPENEEFSYCRENNL SIKHRSEILAMLMRTYTALAVAGSHGKTSTSTFLSTILELCTRNSSSITGGIIPIYNSNCHLDNTKYLVAEVDESDGTIN KYKSDIGIINNIDFDHCDHFSNLNEVISTFKSFAKNSKKLLLNFDCETSRNNFYSNWKWSNSTAKNVTYAIIPIEINSKY TIGKYYENGNFISSLNIPIPGLHNLSNITAAIAASRMIGVDFIEIKKNIKYLKLPKKRFEFRGQLDERSLYDDYAHHPNE IKETIKLGRLLIQQNHNKECQKSRLIAIFQPHRYSRVKQFTKEFAEELSKADVIYVTSIYGAGEGNEDRITSKIITDLIY KKNKNVSYINNYYEVTKNFYELTQKGDLILNMGAGDCHNFWSILNKNN >Mature_447_residues SALAIGLLKKGYSVSGSDLVKNDETNKLEKLGAVIFNSQVRQNIEFIISKFTNKLIYFVVSSAIKPENEEFSYCRENNLS IKHRSEILAMLMRTYTALAVAGSHGKTSTSTFLSTILELCTRNSSSITGGIIPIYNSNCHLDNTKYLVAEVDESDGTINK YKSDIGIINNIDFDHCDHFSNLNEVISTFKSFAKNSKKLLLNFDCETSRNNFYSNWKWSNSTAKNVTYAIIPIEINSKYT IGKYYENGNFISSLNIPIPGLHNLSNITAAIAASRMIGVDFIEIKKNIKYLKLPKKRFEFRGQLDERSLYDDYAHHPNEI KETIKLGRLLIQQNHNKECQKSRLIAIFQPHRYSRVKQFTKEFAEELSKADVIYVTSIYGAGEGNEDRITSKIITDLIYK KNKNVSYINNYYEVTKNFYELTQKGDLILNMGAGDCHNFWSILNKNN
Specific function: Cell wall formation [H]
COG id: COG0773
COG function: function code M; UDP-N-acetylmuramate-alanine ligase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family [H]
Homologues:
Organism=Escherichia coli, GI1786279, Length=456, Percent_Identity=27.8508771929825, Blast_Score=149, Evalue=3e-37, Organism=Escherichia coli, GI1790680, Length=404, Percent_Identity=24.7524752475248, Blast_Score=112, Evalue=4e-26,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR016040 - InterPro: IPR005758 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.8 [H]
Molecular weight: Translated: 51080; Mature: 50948
Theoretical pI: Translated: 9.08; Mature: 9.08
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 0.9 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSALAIGLLKKGYSVSGSDLVKNDETNKLEKLGAVIFNSQVRQNIEFIISKFTNKLIYFV CCHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH VSSAIKPENEEFSYCRENNLSIKHRSEILAMLMRTYTALAVAGSHGKTSTSTFLSTILEL HHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHH CTRNSSSITGGIIPIYNSNCHLDNTKYLVAEVDESDGTINKYKSDIGIINNIDFDHCDHF HCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCHHHHHCCCCEEECCCHHHHHHH SNLNEVISTFKSFAKNSKKLLLNFDCETSRNNFYSNWKWSNSTAKNVTYAIIPIEINSKY HHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEECCCCCCCEEEEEEEEEECCEE TIGKYYENGNFISSLNIPIPGLHNLSNITAAIAASRMIGVDFIEIKKNIKYLKLPKKRFE EEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCEEECCHHHHH FRGQLDERSLYDDYAHHPNEIKETIKLGRLLIQQNHNKECQKSRLIAIFQPHRYSRVKQF HCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCEEEEECCCHHHHHHHH TKEFAEELSKADVIYVTSIYGAGEGNEDRITSKIITDLIYKKNKNVSYINNYYEVTKNFY HHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH ELTQKGDLILNMGAGDCHNFWSILNKNN HHHCCCCEEEECCCCCHHHHHHHHCCCC >Mature Secondary Structure SALAIGLLKKGYSVSGSDLVKNDETNKLEKLGAVIFNSQVRQNIEFIISKFTNKLIYFV CHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH VSSAIKPENEEFSYCRENNLSIKHRSEILAMLMRTYTALAVAGSHGKTSTSTFLSTILEL HHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHH CTRNSSSITGGIIPIYNSNCHLDNTKYLVAEVDESDGTINKYKSDIGIINNIDFDHCDHF HCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCHHHHHCCCCEEECCCHHHHHHH SNLNEVISTFKSFAKNSKKLLLNFDCETSRNNFYSNWKWSNSTAKNVTYAIIPIEINSKY HHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEECCCCCCCEEEEEEEEEECCEE TIGKYYENGNFISSLNIPIPGLHNLSNITAAIAASRMIGVDFIEIKKNIKYLKLPKKRFE EEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCEEECCHHHHH FRGQLDERSLYDDYAHHPNEIKETIKLGRLLIQQNHNKECQKSRLIAIFQPHRYSRVKQF HCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCEEEEECCCHHHHHHHH TKEFAEELSKADVIYVTSIYGAGEGNEDRITSKIITDLIYKKNKNVSYINNYYEVTKNFY HHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH ELTQKGDLILNMGAGDCHNFWSILNKNN HHHCCCCEEEECCCCCHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12917642 [H]