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The map label for this gene is bmrR [H]

Identifier: 126701210

GI number: 126701210

Start: 4182518

End: 4183375

Strand: Direct

Name: bmrR [H]

Synonym: CD3583

Alternate gene names: 126701210

Gene position: 4182518-4183375 (Clockwise)

Preceding gene: 126701209

Following gene: 126701222

Centisome position: 97.49

GC content: 26.34

Gene sequence:

>858_bases
ATGAGTAAAAAATTTTCAATAGGAGAAATGTCTAAACTTCATAAAATAAGCATACAGACACTAAGGTACTATGACCAAAT
AGATTTATTTAAACCTGTTCATGTTGACCAAGAAAGCAATTACAGATATTACTCAATTGACCAATTTTCACAATTAGATA
TTATAAAATATTTAAAATATTTAGGTATGCCTTTAAAAGAAATTAAGTCAAAGCTTGATGAAAATAATGAAGAAATTCTA
AAATTACTAACAAATAAAATTAATATAGTGGATGAAAAAATTAAAGAATTAGAGCTTATAAAGAAGGTACTAAGCACAAA
GAAAGAAACTATGGAAAAAGGTATGAAAGTAGATGAAGTTGGTAAAATAGTGAGAAAACATATTCCACGAAGAAGTATCT
TATCTATAGAGTATGAAGAAGGATTAAGTAGTGAAGAAACTATGGAACTTTCCAGAAGACAAATAGCAAATATATTAGAA
GATAATATATCTGTGTTCTATGGTGGAGTAAGTGGACTTGTATCTATAGATAAATTTTTAAAAGAAGATAAAGTTATTTA
TGACAATAGTTTTGTTACTGTTGAAAGAGACTTATTTGATATAAAATCACAAAAACATATAACAGAAATTTCATCTGGTG
ATTTTATTTGTATGACATATAAAGGGCCTTACAAAGAAAATTATACCGCTTTTAAGAAACTGGTTGATTATGTTGAATAT
AAAAGAATACCCATTGAAAATTATATATATGAAATACCTATAATAGACCCTCTGTCTACAAACAACGAAGAGGAACTTCT
AACAGAAATTCAAATACAAGTTAAAAAGAGAGAAATTGACTTAAGATGTCTAGTGTAG

Upstream 100 bases:

>100_bases
AAATTTGCCATCCTACTACAAAAGAAAAAATGGAATTTACATGTCATCCACCTGACAAATATCCATGGAATATATTTTAA
ATCTCAAATGAGGTGATTAT

Downstream 100 bases:

>100_bases
TAATCTAGTTTACTTACACATCTTAATATAGTTGTCTATTATCAACATATGATTTTTCTAGATAGTGATTCCTAACAGTG
AGATTTTCAAAAAATAGGAG

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYYSIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEIL
KLLTNKINIVDEKIKELELIKKVLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICMTYKGPYKENYTAFKKLVDYVEY
KRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKKREIDLRCLV

Sequences:

>Translated_285_residues
MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYYSIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEIL
KLLTNKINIVDEKIKELELIKKVLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICMTYKGPYKENYTAFKKLVDYVEY
KRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKKREIDLRCLV
>Mature_284_residues
SKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYYSIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILK
LLTNKINIVDEKIKELELIKKVLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILED
NISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICMTYKGPYKENYTAFKKLVDYVEYK
RIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKKREIDLRCLV

Specific function: Activates transcription of the bmr gene in response to structurally dissimilar drugs. Binds rhodamine as an inducer [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010499
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011256 [H]

Pfam domain/function: PF06445 AraC_E_bind; PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 33584; Mature: 33453

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYYSIDQFSQLDIIKYLKY
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHH
LGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKKVLSTKKETMEKGMKVDEV
HCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILEDNISVFYGGVSGLVSIDKFL
HHHHHHHCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHCCHHEEECCHHHHHHHHHHH
KEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICMTYKGPYKENYTAFKKLVDYVEY
HCCCEEECCCEEEEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
KRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKKREIDLRCLV
CCCCHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure 
SKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYYSIDQFSQLDIIKYLKY
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHH
LGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKKVLSTKKETMEKGMKVDEV
HCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILEDNISVFYGGVSGLVSIDKFL
HHHHHHHCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHCCHHEEECCHHHHHHHHHHH
KEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICMTYKGPYKENYTAFKKLVDYVEY
HCCCEEECCCEEEEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
KRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKKREIDLRCLV
CCCCHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7961792; 8969508; 9384377; 10568751; 10025401; 11201751 [H]