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The map label for this gene is uxaA [H]

Identifier: 126700488

GI number: 126700488

Start: 3358914

End: 3360077

Strand: Direct

Name: uxaA [H]

Synonym: CD2872

Alternate gene names: 126700488

Gene position: 3358914-3360077 (Clockwise)

Preceding gene: 126700487

Following gene: 126700489

Centisome position: 78.29

GC content: 35.4

Gene sequence:

>1164_bases
ATGAAATTAATGGGTTATTTAAGAGAAAATGGTCAGTTTGGTATTCGTAATCATGTTTTAATTATTCCAACATCTGTATG
TTCAAGTGAGACAGCTACAAGAATAGCATCACTTGTGCCTGGAGCAATAGCAATCCCTCATCAACATGGATGTTGTCAAA
TTGGTTCTGATATAGAGCTTACAGCAAAGACATTAATAGGATTTGGAAAAAATCCTAATGTTGCCGCAGTTTTAGTAGTT
GGTCTTGGATGTGATGGTATTCAAGCAAAAGAATTAGCATCTGAAATAGCTACAACAGGAAAAAAGGTAGATTACGTTGT
TATACAAGAATGTGGCGGAACATTAAAAACAGTTTCTAAGGGAGCTGAAATAGTAAGTAAAATGGCTCGTGAAGTATCAA
AAGAAGTAAGAGTTGAATTTGGTATGAGTGAAATTACATTAGCACTTGAATGTGGTGGTTCTGACCCAACAAGTGGAATA
GCTTCAAACCCTTCAATAGGCGTTGCATCAAACCTTCTTGTAGATGAAGGTGGAAGTAGCATACTAAGTGAAACTACAGA
AGTAATTGGTGCAGAACATTTGTTGGCTACCCGTTTTGAAGATGAAGAAATGAAAGATAAGTTTCTTAAATTTGTAAGTG
ATGTAGAAAAAAGAGCAATTGCTATGGGAGAAGATTTACGTAGTGGTCAACCTACTCCAGGCAATAAAACTGGTGGACTT
TCAACAATTGAAGAAAAGTCACTTGGGTGTATGTATAAGGCAGGCAATAAGCCATTCAAAGGTGCTCTTGAATATGCTGA
TATTGTACCTCCTGATAAAAAAGGATTATATTTTATGGATACTCCAGGTCAAGATATAGATTCTATCACTGGTATGGTAG
CAGGTGGTGCACAAATTGTAATCTTTTCAACTGGTAGAGGTACTCCAACAGGAAGCCCTATTTCACCAGTTATTAAAATC
ACTGGGAATAGTGATACATACAACAAAATGCCAGACAATATCGATATAAATGCAGGTAGAATTATAACAGATGGTGCTAA
AATAGCAGATATAGGTCAAGAAATATTTAATGAAATAATAGAAGTCTGTAATGGTAAACATACCAAAGCTGAAAGTCTTG
GTCATAGAGAATTTGGCATTTACAGAATTTCATCTACATTTTAG

Upstream 100 bases:

>100_bases
AGGAATTGCAACAGTTGACATAAAAACTGGTGACTATGTTCATGTACATAACATTGAAAGTACACGTGGTCGTGGAGATA
AAAAATAGGAGGAAGTTAAA

Downstream 100 bases:

>100_bases
ATTGTAACAAAATATCTTTTATAAATATAATACTTATGTAGATACATAAGCTAAAAGTTCTTTCTAATACTATAAAAATT
TTCTATACTGAAAAGGAACT

Product: altronate hydrolase

Products: NA

Alternate protein names: Altronic acid hydratase [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIAIPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVV
GLGCDGIQAKELASEIATTGKKVDYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKRAIAMGEDLRSGQPTPGNKTGGL
STIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGLYFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKI
TGNSDTYNKMPDNIDINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF

Sequences:

>Translated_387_residues
MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIAIPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVV
GLGCDGIQAKELASEIATTGKKVDYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKRAIAMGEDLRSGQPTPGNKTGGL
STIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGLYFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKI
TGNSDTYNKMPDNIDINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF
>Mature_387_residues
MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIAIPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVV
GLGCDGIQAKELASEIATTGKKVDYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKRAIAMGEDLRSGQPTPGNKTGGL
STIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGLYFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKI
TGNSDTYNKMPDNIDINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789475, Length=388, Percent_Identity=33.5051546391753, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1789516, Length=403, Percent_Identity=31.7617866004963, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.7 [H]

Molecular weight: Translated: 40893; Mature: 40893

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIAIPHQHGCCQIGSDIEL
CCCCHHHHCCCCCCCCCCEEEEECHHCCCHHHHHHHHHCCCCEECCCCCCCEECCCCCEE
TAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKKVDYVVIQECGGTLKTVSK
EHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHH
GAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGIASNPSIGVASNLLVDEGGSS
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCH
ILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKRAIAMGEDLRSGQPTPGNKTGGL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCC
STIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGLYFMDTPGQDIDSITGMVAGGAQIV
CHHHHHCCCEEEECCCCCCCCHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHCCCCEEEE
IFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNIDINAGRIITDGAKIADIGQEIFNEII
EEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCEECCCCEEEECCCHHHHHHHHHHHHHH
EVCNGKHTKAESLGHREFGIYRISSTF
HHHCCCCCCHHHCCCCCEEEEEEECCC
>Mature Secondary Structure
MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIAIPHQHGCCQIGSDIEL
CCCCHHHHCCCCCCCCCCEEEEECHHCCCHHHHHHHHHCCCCEECCCCCCCEECCCCCEE
TAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKKVDYVVIQECGGTLKTVSK
EHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHH
GAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGIASNPSIGVASNLLVDEGGSS
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCH
ILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKRAIAMGEDLRSGQPTPGNKTGGL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCC
STIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGLYFMDTPGQDIDSITGMVAGGAQIV
CHHHHHCCCEEEECCCCCCCCHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHCCCCEEEE
IFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNIDINAGRIITDGAKIADIGQEIFNEII
EEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCEECCCCEEEECCCHHHHHHHHHHHHHH
EVCNGKHTKAESLGHREFGIYRISSTF
HHHCCCCCCHHHCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]