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The map label for this gene is stc [H]

Identifier: 126700485

GI number: 126700485

Start: 3355444

End: 3357360

Strand: Direct

Name: stc [H]

Synonym: CD2869

Alternate gene names: 126700485

Gene position: 3355444-3357360 (Clockwise)

Preceding gene: 126700484

Following gene: 126700486

Centisome position: 78.21

GC content: 28.69

Gene sequence:

>1917_bases
TTGATGAAATATGGAGGAATTATTATGAAGGAAATACTTGTTATTGCTCCCACTAAAGGAACCTATGAAAAATCAATTCA
CATAGTTAAAAAAAACAAATATAAAACTATTGATGTTGTATTTGGCAATCTAAAAGAAGGTATACCTCTTGCTGAAAAAA
GTATTAATCATGGTACTAGAATTATCATAAGCCGAGGTGGAACTTACAATATGTTAAAAGCTACTTACAATATACCTATA
GTTGAAATTAAGGTAGATGCTTATGATATTATAAAAAGCTACAAAGAGGTAAAAAATTCCAATGAACCATTTGGAATAAT
TGGATTTAATAATGTCATCTACGGTTTCGATATTATAGAAGAAATATTGAATAAGAAAATAACTATGATTGAAATTGAAA
AAGAAGAAGAAATTTATGATGCTATAGAAAAGTACAGAAAGAAAGGTATAAACACATATATAGGAGATACCACTGTTGCA
CATATTGTTAAGAGACTTAATTGTAAGGGAATATTAATCGAATCTAGAGAAGAAAACATACTTAGAGCCATTCAACAAGC
AGAACAAATACTCGAAGCAACCAAGGATGAACAAAAAAGAAGATTACAGATAGAAGCTATGACAGATTTTGTACATGATG
GAATAATAACAGTTGATAAAAATTTTAAAATAACATTATTTAATAAGAGTGCTGAAAAAATATTTGGTATAAAAAAAGAA
AATGCACTTTATCATAATGTTGTAGATGTTATCCCAAACACAGTTCTTCCACAAGTAGTTGAGACTATGGAACCTCAAAT
TGGTGAAATACAAAATATAGGGAGTACAAAAATTATTACAAATAGAGTTCCAATCATTGTTGATGGTCAGATTCAAGGGG
CTGTTTCAACATTTCAAGATAGCAAGGAGATAAGTTCTTTTGAACATACAATAAGAAGGAGCTTATTAAGCAAAGGTCTA
TCTGCTAAATACACTTTTGATGATATAATTCATGCTAGTAAAAAGACAAAAGATTGTATAGAACTTGCAAAAAAATATGC
TTGTTATGATACTCCTATGATTATTACTGGAGAATCTGGAGTTGGTAAAGAACTATTTTGTCAAAGTATACATAACTATA
GTAAGCGTAAAAATGCACCTTTTGTTGCTGTAAATTGTGCTGCCATACCTCCATCTCTAATAGAGAGTGAGTTTTTTGGT
TATGAGGAAGGTTCATTTACAGGTGCTAGAAAAAAAGGTAAAGCAGGTGTATTCGAACTAGCACATGAAGGCACAATCTT
CCTAGATGAAATAAGTGAAATCCCTCTTGAACTTCAAGGTCGATTATTGAGGGTATTGCAGGAAAAACAAGTTATGAGAA
TTGGTGGTGATAAAGTTATTCCTATAGATGTAAAAATTATCTGTGCTTCAAATAAAGACTTAAAAAATATGATGCGCAAT
GGTTTATTTAGACAAGACCTTTATTTTAGAATAAATATACTAACATTATATCTTCCTTCATTAAAAGAAAGAAAAGAAGA
TATTATAAAATTATCAGAATTTTTTATACATAAATATTCAAGCAAATACAATAAAACGCCTTTAATTATCACTCCAAATA
TTAAAAAGGCACTTCTTGAACGAGAATATGAAGGTAATATAAGGGAATTGGAAGGTATGATGGAAAGGGCTGTTATTGTG
GAATCATTTGACTCGATTTTATTAGAAAAGCTTAGCAATGAATATACAAATAATATAGTTGATAAAGATAATAGTGATTT
TGAATGCAGTAATTTAGATTTAAAAACTTTAGAAAAAAAATATATCTATAAAATTTATAACGAAAATAATAGAAATACTA
CAAAAACCTGTGAAATTCTAAAGATAACTCGCTCCACTCTATGGCGTAAGTTAAAAGAAATAGAAGATGATGTTTAA

Upstream 100 bases:

>100_bases
TAATGTTCCTTTTAAAAATACTTTATTTATAATTAAATATAAAGTAAAATGTTAAAATATAACTGATAAAATTTAGTCAT
AAGATAATATTTAAGTTTAT

Downstream 100 bases:

>100_bases
AAATAATACATACCTATATATATCAAAACGTTTTATGTTTAATTTTAATACATAAGACGTTTATTTGTTTTCAATAAAAA
ATACAATTATATGATAAAAA

Product: sigma-54 dependent regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MMKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYKTIDVVFGNLKEGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPI
VEIKVDAYDIIKSYKEVKNSNEPFGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVA
HIVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVDKNFKITLFNKSAEKIFGIKKE
NALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTKIITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGL
SAKYTFDDIIHASKKTKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSLIESEFFG
YEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQVMRIGGDKVIPIDVKIICASNKDLKNMMRN
GLFRQDLYFRINILTLYLPSLKERKEDIIKLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIV
ESFDSILLEKLSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRSTLWRKLKEIEDDV

Sequences:

>Translated_638_residues
MMKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYKTIDVVFGNLKEGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPI
VEIKVDAYDIIKSYKEVKNSNEPFGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVA
HIVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVDKNFKITLFNKSAEKIFGIKKE
NALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTKIITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGL
SAKYTFDDIIHASKKTKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSLIESEFFG
YEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQVMRIGGDKVIPIDVKIICASNKDLKNMMRN
GLFRQDLYFRINILTLYLPSLKERKEDIIKLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIV
ESFDSILLEKLSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRSTLWRKLKEIEDDV
>Mature_638_residues
MMKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYKTIDVVFGNLKEGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPI
VEIKVDAYDIIKSYKEVKNSNEPFGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVA
HIVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVDKNFKITLFNKSAEKIFGIKKE
NALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTKIITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGL
SAKYTFDDIIHASKKTKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSLIESEFFG
YEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQVMRIGGDKVIPIDVKIICASNKDLKNMMRN
GLFRQDLYFRINILTLYLPSLKERKEDIIKLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIV
ESFDSILLEKLSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRSTLWRKLKEIEDDV

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=418, Percent_Identity=34.9282296650718, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1786524, Length=328, Percent_Identity=39.0243902439024, Blast_Score=235, Evalue=8e-63,
Organism=Escherichia coli, GI87082117, Length=251, Percent_Identity=42.6294820717131, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI1789233, Length=440, Percent_Identity=31.3636363636364, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1790299, Length=329, Percent_Identity=33.434650455927, Blast_Score=210, Evalue=3e-55,
Organism=Escherichia coli, GI1789087, Length=235, Percent_Identity=43.4042553191489, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1790437, Length=288, Percent_Identity=38.8888888888889, Blast_Score=208, Evalue=1e-54,
Organism=Escherichia coli, GI1788905, Length=299, Percent_Identity=35.1170568561873, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1787583, Length=426, Percent_Identity=29.1079812206573, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI87082152, Length=227, Percent_Identity=40.0881057268723, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI87081872, Length=309, Percent_Identity=33.0097087378641, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI87081858, Length=454, Percent_Identity=25.5506607929515, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1789828, Length=237, Percent_Identity=30.8016877637131, Blast_Score=125, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 73033; Mature: 73033

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYKTIDVVFGNLKEGIPLAEKSINHGTR
CCCCCHHHHCCCEEEECCCCCCCCEEEEEECCCCEEEEEEECCHHCCCCHHHHCCCCCCE
IIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEPFGIIGFNNVIYGFDIIE
EEEECCCCEEEEEEEECCEEEEEEECHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
EILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAHIVKRLNCKGILIESREENI
HHHCCCEEEEEECCHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHCCCCEEEEECCHHHH
LRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVDKNFKITLFNKSAEKIFGIKKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEECCCHHHHCCCCCC
NALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTKIITNRVPIIVDGQIQGAVSTFQD
CCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCEEECCCCHHHHHHHHH
SKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASKKTKDCIELAKKYACYDTPMIITGESG
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCC
VGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSLIESEFFGYEEGSFTGARKKGKAGVFEL
CCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHEE
AHEGTIFLDEISEIPLELQGRLLRVLQEKQVMRIGGDKVIPIDVKIICASNKDLKNMMRN
CCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCHHHHHHHHC
GLFRQDLYFRINILTLYLPSLKERKEDIIKLSEFFIHKYSSKYNKTPLIITPNIKKALLE
CCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHH
REYEGNIRELEGMMERAVIVESFDSILLEKLSNEYTNNIVDKDNSDFECSNLDLKTLEKK
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHH
YIYKIYNENNRNTTKTCEILKITRSTLWRKLKEIEDDV
HHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYKTIDVVFGNLKEGIPLAEKSINHGTR
CCCCCHHHHCCCEEEECCCCCCCCEEEEEECCCCEEEEEEECCHHCCCCHHHHCCCCCCE
IIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEPFGIIGFNNVIYGFDIIE
EEEECCCCEEEEEEEECCEEEEEEECHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
EILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAHIVKRLNCKGILIESREENI
HHHCCCEEEEEECCHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHCCCCEEEEECCHHHH
LRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVDKNFKITLFNKSAEKIFGIKKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEECCCHHHHCCCCCC
NALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTKIITNRVPIIVDGQIQGAVSTFQD
CCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCEEECCCCHHHHHHHHH
SKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASKKTKDCIELAKKYACYDTPMIITGESG
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCC
VGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSLIESEFFGYEEGSFTGARKKGKAGVFEL
CCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHEE
AHEGTIFLDEISEIPLELQGRLLRVLQEKQVMRIGGDKVIPIDVKIICASNKDLKNMMRN
CCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCHHHHHHHHC
GLFRQDLYFRINILTLYLPSLKERKEDIIKLSEFFIHKYSSKYNKTPLIITPNIKKALLE
CCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHH
REYEGNIRELEGMMERAVIVESFDSILLEKLSNEYTNNIVDKDNSDFECSNLDLKTLEKK
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHH
YIYKIYNENNRNTTKTCEILKITRSTLWRKLKEIEDDV
HHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA