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The map label for this gene is ctfA [H]

Identifier: 126700291

GI number: 126700291

Start: 3093251

End: 3093907

Strand: Direct

Name: ctfA [H]

Synonym: CD2677

Alternate gene names: 126700291

Gene position: 3093251-3093907 (Clockwise)

Preceding gene: 126700290

Following gene: 126700292

Centisome position: 72.1

GC content: 32.88

Gene sequence:

>657_bases
ATGAATAAAATAGTTAGCATTGATGAAGCTCTATCTCATGTAAAAGATGGAGATACAATAATGGTTGGTGGATTCATGGC
CAATGGTTCACCAGAAAATTTAATTGATTATTTATGTAGTAAAAATATAAAAGATTTGACACTAATTTGCAATGATACTG
GCTTTATTGACAAAGGAGTTGGCAAAATGGTTGTAAATAAGCAATTTAAAAAGATAATTGCTTCTCATGTAGGATTAAAT
AAAGAAACTGGAAGACAAATGAACAACAATGAAACAGATGTTGAGTTAGTTCCTCAGGGAACTCTTGCTGAACAAATACG
TGCAGCTGGTTATGGTCTAGGAGGTATACTCACACCGACTGGTATTGGTACTCTTGTTGAGGAGGGAAAGCAAAAAATTG
TTGTCGATAGCAAAGAATACCTTCTTGAAAAACCAATTTATGCAGATGTTGCTCTTCTATTTGCATCAAAGGTCGATAAA
GCAGGTAATCTAGTTTATAAAGGCTCTATGAACAATTTTAATAATTTAATGGCATCTGCTGCCAAAATTACAATAGTTGA
ATCAGATGAAATCGTTGAAATTGGTGATATTGACCCAAATGAAGTTAATACACCAGGTATTTTTGTGAATTACATCGTTG
AAGGAGGTAATTTATAA

Upstream 100 bases:

>100_bases
TTTATGAAATGCAAAAACGTAAAGTTGAAACTGGACTTGCAACACTTTGTATTGGTGGTGGTCAAGGAATATCAATGGTG
GTTTCACGATAGGAGGAAAT

Downstream 100 bases:

>100_bases
TGGATAAATTAGAAATGCAAGAATATATTGCAAATAGAGTATCTAAAGAATTAAAAGACGGAGCCGTTGTAAACCTTGGA
ATAGGTCTACCAACCAAAGT

Product: butyrate--acetoacetate CoA-transferase subunit A

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit alpha [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIKDLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLN
KETGRQMNNNETDVELVPQGTLAEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
AGNLVYKGSMNNFNNLMASAAKITIVESDEIVEIGDIDPNEVNTPGIFVNYIVEGGNL

Sequences:

>Translated_218_residues
MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIKDLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLN
KETGRQMNNNETDVELVPQGTLAEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
AGNLVYKGSMNNFNNLMASAAKITIVESDEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
>Mature_218_residues
MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIKDLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLN
KETGRQMNNNETDVELVPQGTLAEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
AGNLVYKGSMNNFNNLMASAAKITIVESDEIVEIGDIDPNEVNTPGIFVNYIVEGGNL

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=225, Percent_Identity=42.2222222222222, Blast_Score=175, Evalue=3e-44,
Organism=Homo sapiens, GI11545841, Length=225, Percent_Identity=39.5555555555556, Blast_Score=153, Evalue=1e-37,
Organism=Escherichia coli, GI1788551, Length=212, Percent_Identity=52.8301886792453, Blast_Score=246, Evalue=6e-67,
Organism=Escherichia coli, GI1787985, Length=238, Percent_Identity=25.6302521008403, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531517, Length=232, Percent_Identity=41.3793103448276, Blast_Score=169, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21358325, Length=227, Percent_Identity=42.2907488986784, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24655794, Length=227, Percent_Identity=42.2907488986784, Blast_Score=174, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 23453; Mature: 23453

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIKDLTLICNDTGFIDKGV
CCCEECHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCH
GKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTLAEQIRAAGYGLGGILTPT
HHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCC
GIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDKAGNLVYKGSMNNFNNLMASA
CHHHHHHCCCCEEEECCHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHH
AKITIVESDEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
EEEEEEECCCEEEECCCCCCCCCCCCEEEEEEEECCCC
>Mature Secondary Structure
MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIKDLTLICNDTGFIDKGV
CCCEECHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCH
GKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTLAEQIRAAGYGLGGILTPT
HHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCC
GIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDKAGNLVYKGSMNNFNNLMASA
CHHHHHHCCCCEEEECCHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHH
AKITIVESDEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
EEEEEEECCCEEEECCCCCCCCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]