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The map label for this gene is appB [H]

Identifier: 126700287

GI number: 126700287

Start: 3088817

End: 3089776

Strand: Direct

Name: appB [H]

Synonym: CD2673

Alternate gene names: 126700287

Gene position: 3088817-3089776 (Clockwise)

Preceding gene: 126700286

Following gene: 126700288

Centisome position: 72.0

GC content: 27.5

Gene sequence:

>960_bases
ATGTTAAAATTAATATTGAATAGAGTAAAAGTTTTAATACCTATGTTAATCTTAATATCTATATTATCATTTGGACTTTT
AGAATTAGCTCCTGGTGACCCAGCAGATGCATATATAAATCCTTTAATGTCTTCACAGGATATTGAAAATATAAGGGTTA
ATATGGGACTTGATAAACCAGTATATATAAGATATTTAAACTGGTTGAAAAACACTTTAAGTGGAAACTTAGGTATTTCT
TATATAAACCATATGCCCGTTACAGAACAAATTATGGAAAAAATGGGAAATACATTTATTCTTATGGGTACTTCTTTGAT
ATTTTCAATATTGGTAGCTATACCTCTTGGAATATTTTTAGCTGTAAATAAAAATTCAATAACTAGTAAAGTATCATCTG
TTTTTAATTATATAGGTGTTTCTATACCTTCTTTTTGGATAGGTATGATACTCATTTCAATTTTTTCAGTTAAACTTAAC
ATTTTCCCATCAGGAGGTATGCATACTATTGGAAATGATAGTATTGGAGATTTAGTAAAACATTTAGTTTTGCCTGTAAT
AACTTTAGGTCTATATAATACTGCTATTTTTACAAATTATGTAGAAGCTAGTGTAAATGAACAATTAAAAAAACAATATG
TTATTACAGCAAGAGCAAAAGGATTATCAGAAAAAGTCATACTATTTAAACATGTCTTGAAAAATTCACTGACATCATTG
GTTACAATCCTAGGCATGAGTATACAAAAATTAGTCACTGGTGCATTTGTTACAGAAGTAGTTTTCTCTTGGCCAGGTAT
GGGAAGATTAATGATTGATTCAATTTTTTCAAGAGATTATACTGTAATTATGGCAATAACTATGTTATCAGCACTATTTT
TAATTTTAGGTAATTTAGTTGCTGATATACTATACTTATTAATTGACCCTAAAATAAAATCTAGCAAAGGAGGATTCTAG

Upstream 100 bases:

>100_bases
GTAAAATTTTATATTATTAATTAGAAAAGGAGATGTCTAAAAATAATATTGTTTTATTATTTTAAAACGAGACATCTCTT
TTAATTAGGAGAATTTACTT

Downstream 100 bases:

>100_bases
TTGTGTTTACAAGTATCTTAAAAAAATTAAAAAAAGATAAATCCTTTGCTTTTGCATGTATTACTCTTAGCATAATAATC
ATATTAATTATAGCTTCTTT

Product: oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMSSQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGIS
YINHMPVTEQIMEKMGNTFILMGTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITARAKGLSEKVILFKHVLKNSLTSL
VTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIFSRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF

Sequences:

>Translated_319_residues
MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMSSQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGIS
YINHMPVTEQIMEKMGNTFILMGTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITARAKGLSEKVILFKHVLKNSLTSL
VTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIFSRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF
>Mature_319_residues
MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMSSQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGIS
YINHMPVTEQIMEKMGNTFILMGTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITARAKGLSEKVILFKHVLKNSLTSL
VTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIFSRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=313, Percent_Identity=37.6996805111821, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1789965, Length=343, Percent_Identity=34.1107871720117, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1789888, Length=321, Percent_Identity=31.4641744548287, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1787761, Length=335, Percent_Identity=31.6417910447761, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1787497, Length=314, Percent_Identity=28.9808917197452, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788504, Length=362, Percent_Identity=30.6629834254144, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=29.1044776119403, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35152; Mature: 35152

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMSSQDIENIRVNMGLDKP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCH
VYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILMGTSLIFSILVAIPLGIFL
HHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHEE
AVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLNIFPSGGMHTIGNDSIGDLVK
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHH
HLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITARAKGLSEKVILFKHVLKNSLTSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIFSRDYTVIMAITMLSALFLILGNLV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ADILYLLIDPKIKSSKGGF
HHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMSSQDIENIRVNMGLDKP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCH
VYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILMGTSLIFSILVAIPLGIFL
HHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHEE
AVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLNIFPSGGMHTIGNDSIGDLVK
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHH
HLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITARAKGLSEKVILFKHVLKNSLTSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIFSRDYTVIMAITMLSALFLILGNLV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ADILYLLIDPKIKSSKGGF
HHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]