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The map label for this gene is appC [H]

Identifier: 126700288

GI number: 126700288

Start: 3089779

End: 3090591

Strand: Direct

Name: appC [H]

Synonym: CD2674

Alternate gene names: 126700288

Gene position: 3089779-3090591 (Clockwise)

Preceding gene: 126700287

Following gene: 126700290

Centisome position: 72.02

GC content: 29.77

Gene sequence:

>813_bases
GTGTTTACAAGTATCTTAAAAAAATTAAAAAAAGATAAATCCTTTGCTTTTGCATGTATTACTCTTAGCATAATAATCAT
ATTAATTATAGCTTCTTTTATATTAAATATAGACTCTAATGCAATTGATACTACTTCTAAACTTCAAGAACCTAGCTTAA
AGCATATCTTTGGTACAGACGAACTTGGTAGAGATTACTTCTCTAGAGCTCTTTATGGTGGAAGGATTTCACTTAGTGTT
GGTATTTTATCAATGCTTATTTCTGTAGTATTTGGTACTGCTGTAGGTGTTATTAGTGGATATATTGGAGGTAAGCTGGA
CCAATTCTTGATGAGATTAGTGGATATGCTTATGAGTATACCAAGTTTCTTAGTTTTGATTGTATTAAATACTTATCTAA
CACCTAAAGTTTCCACTATTATACTAATTATTGGATTCTTAAGTTGGATGGAAGTTTCAAGAATTGTACGTGGCGAAACA
TTAAAAATAAAGGAAAATGAATACTGTCTAGCTGCTAAAGCTACTGGTATCAAGACTAGAAATATACTATTAAGACATAT
AGTTTTAAACTTAAAAGAGACTATTGTAGTTGCTGGTTCGTTAAATATTGCTAATGCTATCTTAACTGAATCTGCTCTTA
GTTTTTTAGGTCTTGGAATCCAATTGCCTCTTGCATCATGGGGTAATATGCTTCAAGATGCTCAAAGACATATTTTTGAC
AAGTTATATTTAGCTGTATTTCCAGGATTACTTATATTTTTAACAGTCATGAGTTTGACTATAATAAGCAAAAAATTTTC
TAGTAATACTTAA

Upstream 100 bases:

>100_bases
TGTTATCAGCACTATTTTTAATTTTAGGTAATTTAGTTGCTGATATACTATACTTATTAATTGACCCTAAAATAAAATCT
AGCAAAGGAGGATTCTAGTT

Downstream 100 bases:

>100_bases
CAAATTTTATATAGAAAATAAAAACAGTGATTATCTAAAGATATACACTGTTTTTATTTTTCGTTTAAAAAAATACATAT
TTTGTATATTATAACTTTAA

Product: oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDTTSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSV
GILSMLISVVFGTAVGVISGYIGGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGLGIQLPLASWGNMLQDAQRHIFD
KLYLAVFPGLLIFLTVMSLTIISKKFSSNT

Sequences:

>Translated_270_residues
MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDTTSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSV
GILSMLISVVFGTAVGVISGYIGGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGLGIQLPLASWGNMLQDAQRHIFD
KLYLAVFPGLLIFLTVMSLTIISKKFSSNT
>Mature_270_residues
MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDTTSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSV
GILSMLISVVFGTAVGVISGYIGGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGLGIQLPLASWGNMLQDAQRHIFD
KLYLAVFPGLLIFLTVMSLTIISKKFSSNT

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=244, Percent_Identity=34.8360655737705, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787054, Length=256, Percent_Identity=34.765625, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1787498, Length=248, Percent_Identity=39.5161290322581, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789889, Length=243, Percent_Identity=32.5102880658436, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1789964, Length=213, Percent_Identity=35.2112676056338, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788505, Length=207, Percent_Identity=31.4009661835749, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1787549, Length=264, Percent_Identity=29.1666666666667, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29725; Mature: 29725

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDTTSKLQEPSLKHIFGTD
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHCCCH
ELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYIGGKLDQFLMRLVDMLMSI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
PSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGETLKIKENEYCLAAKATGIKTR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCHHH
NILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGLGIQLPLASWGNMLQDAQRHIFD
HHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KLYLAVFPGLLIFLTVMSLTIISKKFSSNT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDTTSKLQEPSLKHIFGTD
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHCCCH
ELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYIGGKLDQFLMRLVDMLMSI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
PSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGETLKIKENEYCLAAKATGIKTR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCHHH
NILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGLGIQLPLASWGNMLQDAQRHIFD
HHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KLYLAVFPGLLIFLTVMSLTIISKKFSSNT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]