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The map label for this gene is engD [H]

Identifier: 126700276

GI number: 126700276

Start: 3072487

End: 3073584

Strand: Direct

Name: engD [H]

Synonym: CD2662

Alternate gene names: 126700276

Gene position: 3072487-3073584 (Clockwise)

Preceding gene: 126700239

Following gene: 126700279

Centisome position: 71.62

GC content: 31.24

Gene sequence:

>1098_bases
ATGAAATTAGGTATAGTTGGTTTACCAAATGTAGGTAAAAGCACACTATTTAACGCAATAACTCAAGCAGGTGCAGAATC
TGCAAATTACCCTTTTTGTACAATAGACCCAAATGTGGGAGTTGTATCTGTTCCAGATGAAAGATTAAACAAACTACAAG
AATTATATAATTCTGAAAAAATAGTTCCTACTGCTATAGAATTTTGTGATATAGCAGGTTTAGTTAGAGGAGCTTCTAAA
GGAGAAGGTTTAGGAAATAAATTCTTATCACATATAAGAGAAGTTGATGCAATAGTTCATGTTGTTAGATGTTTTGAGGA
TGAAAATGTTGTACATGTAGATGGTTCTGTAGACCCACTTCGTGATATAGAAACTATAAACTTAGAATTAATTTTCTCAG
ATATAGAGATTCTTGAAAGAAGAATTAATAAAACTCAAAAAGCTGCTAAGGCTGATAAAACTTTAGGTTCTGAACTTGAT
TTATTAAAATCAATAATGTCTACTTTAGAAGAAAGTAAGTGTGTAAGAACTATGGAATTTACAGAAGATGAACAAACATT
CGTAAATTCATTGGATTTACTTACATCTAAGCCTGTAATATATGCTTCAAATGTATCAGAAGATGATTTAGCTGATAATG
GAGAAAATAATAAATATGTTCAACAAGTTAAAGCATTTGCAGAAACAGAAGATGCCGAAGTTGTTGTAGTATGTGCACAA
ATAGAAGCAGAAATTTCTGAACTTGATTCTGCTGAAGAAAAGAAAGAGTTTTTAGAAACATTAGGTCTTGAACAATCAGG
GCTTGATAAGCTTATAAAATCTTCTTATGCTTTACTTGGTTTAATTTCATTCTTAACTGCTGGTCCAAAAGAAGTTAGAG
CATGGACTATAAAAGTTGGAAGTAAAGCTCCTCAGGCAGGAGGAAAAATACATTCTGATATAGAAAGAGGATTTATCAGA
GCAGAAACAATAGCCTTTAATGATTTGGTTGAGCATGGTACTATGGCTGCTGCTAAAGAAAAAGGGTTGGTTAAATTAGA
AGGTAAAGAATACATAGTTAAAGATGGAGATGTAATATTATTTAGATTTAATGTTTAA

Upstream 100 bases:

>100_bases
ATATGTATGTCTATAATTAAAACAATTTTGCAATCCTATAGATTGATTGTTTAAAGTTATATAAAGAATATAAAAAAGAA
TAAGAGAGAGGACGATTAAT

Downstream 100 bases:

>100_bases
AATGATTAATCGTATACACTTTGACTATTATATATAATAACTAAAAACTAAGATTATAATAATACAATATTACCTTATAA
TAATTATATAGAATTTAAAA

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSVPDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASK
GEGLGNKFLSHIREVDAIVHVVRCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNKYVQQVKAFAETEDAEVVVVCAQ
IEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSYALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIR
AETIAFNDLVEHGTMAAAKEKGLVKLEGKEYIVKDGDVILFRFNV

Sequences:

>Translated_365_residues
MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSVPDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASK
GEGLGNKFLSHIREVDAIVHVVRCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNKYVQQVKAFAETEDAEVVVVCAQ
IEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSYALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIR
AETIAFNDLVEHGTMAAAKEKGLVKLEGKEYIVKDGDVILFRFNV
>Mature_365_residues
MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSVPDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASK
GEGLGNKFLSHIREVDAIVHVVRCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNKYVQQVKAFAETEDAEVVVVCAQ
IEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSYALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIR
AETIAFNDLVEHGTMAAAKEKGLVKLEGKEYIVKDGDVILFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=371, Percent_Identity=45.822102425876, Blast_Score=322, Evalue=4e-88,
Organism=Homo sapiens, GI58761502, Length=230, Percent_Identity=41.304347826087, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI24308117, Length=111, Percent_Identity=37.8378378378378, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1787454, Length=366, Percent_Identity=54.0983606557377, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1789574, Length=211, Percent_Identity=26.5402843601896, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17509631, Length=367, Percent_Identity=44.4141689373297, Blast_Score=313, Evalue=8e-86,
Organism=Caenorhabditis elegans, GI17552324, Length=241, Percent_Identity=28.2157676348548, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319499, Length=374, Percent_Identity=43.3155080213904, Blast_Score=282, Evalue=6e-77,
Organism=Saccharomyces cerevisiae, GI6321773, Length=380, Percent_Identity=37.6315789473684, Blast_Score=236, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6321649, Length=299, Percent_Identity=30.1003344481605, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6321962, Length=100, Percent_Identity=35, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640873, Length=369, Percent_Identity=43.6314363143631, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24640877, Length=369, Percent_Identity=43.6314363143631, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24640875, Length=369, Percent_Identity=43.6314363143631, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=41.7682926829268, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24585318, Length=138, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40028; Mature: 40028

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSVPDERLNKLQELYNSEK
CCEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHCCCC
IVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVVRCFEDENVVHVDGSVDPL
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
RDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELDLLKSIMSTLEESKCVRTMEF
CCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
TEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNKYVQQVKAFAETEDAEVVVVCAQ
CCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEH
IEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSYALLGLISFLTAGPKEVRAWTIKVG
HHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEC
SKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGTMAAAKEKGLVKLEGKEYIVKDGDVIL
CCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHCHHHHHHHCCCEEECCCEEEEECCCEEE
FRFNV
EEECC
>Mature Secondary Structure
MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSVPDERLNKLQELYNSEK
CCEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHCCCC
IVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVVRCFEDENVVHVDGSVDPL
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
RDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELDLLKSIMSTLEESKCVRTMEF
CCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
TEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNKYVQQVKAFAETEDAEVVVVCAQ
CCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEH
IEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSYALLGLISFLTAGPKEVRAWTIKVG
HHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEC
SKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGTMAAAKEKGLVKLEGKEYIVKDGDVIL
CCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHCHHHHHHHCCCEEECCCEEEEECCCEEE
FRFNV
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]