| Definition | Clostridium difficile 630 chromosome, complete genome. |
|---|---|
| Accession | NC_009089 |
| Length | 4,290,252 |
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The map label for this gene is mngB [H]
Identifier: 126700188
GI number: 126700188
Start: 2970721
End: 2973399
Strand: Direct
Name: mngB [H]
Synonym: CD2569
Alternate gene names: 126700188
Gene position: 2970721-2973399 (Clockwise)
Preceding gene: 126700187
Following gene: 126700212
Centisome position: 69.24
GC content: 28.33
Gene sequence:
>2679_bases ATGAAAAAGACAAAAGTACATGTAGTTCCACACAGTCATTGGGATAGAGAATGGTATTTTACAACATCAAGGTCAAAAAT ATATTTAATGAAAGATTTTCAAGATATATTAGACATATTGGAAGAAAAAGAAGACTTTAAATACTTTACTATGGATGCAC AAGCTTCTCTCTTAGATGATTATTTAAAATGGAGACCTCAGGATGAATATAGAATAAGAGATTTAGTTCAAAGAAGAAGA TTAGTTATTGGACCTTGGTATACTCAAACAGACCAATTGGTTATATCAGGAGAATCTATAATTAGAAACCTTTACTATGG AATAGATAGATGCAATGAATTTGGTGAACCTATGAGGGTTGGATATGTACCAGATTCTTTTGGGCAATCAGCTCAAATGC CACAAATATACAGAGGTTTTGGAATAGATAGTTCATTATTTTGGCGTGGAGTTTCTGATGATATGGTAGATACAACAGAG TTTATATGGAAAGGTTCTGATGGTTCAAAAGTATTAGCAGTTCAAATACCATTTGGTTATTACTATGGAGGTAATATACC AGAAGATGATTCTGATTTAAAAGAATATTTAAAAGATATAATCGGAAAACTTAAGGTTAAAGCTTCTACTAATAACGTAT ATTTTCCAAATGGATTTGACCAAGCACCAATAAGAAAAAACCTTCCTGATATATTAAAAAAAGCTAATGAAATAGATAAT GAAAATGAATACGAAATAAGTGATATAGAAAACTATATAGATTCAGTAAGAAATGAAAGAAATGAATTTACAGAGCTTAA AGGTGAATTTTTAAATGCTAAACATATGAGAATACACAAATCCATATTCTCCTCAAGGTCAGACCTTAAAATAATGAATA ACAAATTAGAAAATTATATTACAAATGTACTTGAACCATTATTAACATTAAGTTATTCACTTGGAAATGAATACCCTCAC CTAGTTATAAAAGATATATGGAAACTTATGTTTGAAAATGCAGCTCATGACAGCATAGGTTCTTGTAATAGTGACACAAC AAATGAGGATGTATACACAAGATACAAACAAGCCAGAGATTTGAGTATAAATTTATTAGATTTGCATATGAGACTTATAA GTACTCAAATCAAAAATAATAATGAAGAAATAACATTAACAGTATTCAATGGATTCCCAGAAGTCAGAAATGAAGTTGTA GAATTTGATACTTATATTCCAGGTCAAGATTTTGTGATAAAGAATAAAAATGGAAAAATTCTTAATTATATAATAAAAGA AAAAGAAGATATTACAAATTATATATTAACTCAAACAATAAGATTAAACCCAAGTAAAAAAATATATATACCCAAAACTG TATATAGAGCAAAAATTGCACTTTCAGTAAAAGATATACCACCAATGGGATATACTCAACTAGTTTTTGAATTGGATACT AAAAATAAATGTGAAATAGAAACAAGTAATTGCAAGGAAATAGAAAACAAATACTACAAAATAACAGCCAATAAAAATGG TTCATTAGAAATATTAGATAAAGAATCTAATAAGACTTATAAAAACCAAGCTGTAATTGAAGACAATGGAGATGATGGAG ATTCATACAACTATTCTCCTCCAAGAAAAGATATTTATGTTTCATCTTTAGATTCTGTATCTTCAGTAGAAGTGCTAAAA TCAAACATTCAAGAAGAAATGATACTTAAATATTCATTGACCATACCAACTTCACTGGAAGAAAGGGCTATAGGTAAAGT TTCTGTGAAAATGCCAGTAACAATGAAAATCACCTTAGAACCTAAAGAACAAATAATTAAGTTTAATGTTAATATAAAAA ATAACCAAGCACTATCTCATAGAGTAAGAGTTTTATTTAATACAGAAATAGCATCTAAGTTTTCTATAGCAGATCAACAA TTTGGAATAATACAAAGACCAACAGTATTAGAAAAAGACCTTGCATTGTGGAAAAGAGACAATTACTCATGGCAAGAAAA ACCTATAACTATCGAACCAATGCAAAGTTTTGTTACTTTAGAGGATGGACAAAGAGGAATAGCATTAATAACTGGTTGTG TAAGAGAATATCAAATAGTTGGTGATAATTTAGATACAATAGCATTAACACTATTCAGGTCATTTGGATATATGGGAAGA GAAAATTTACTTTATAGACCAGGAAGAGCTTCTGGAGAAAAAATAATAGCAACACCAGATGCACAATTACTTAAAGAGTT AAACTTTGACTTTGGTCTTTACATATATAACAATAAATTTGATGAAGCAAATGTAGCTAATACAGCTAAGAGATTCTTAA CACCTATACAAATATATGAATATGCTGATTTTTTAAATGGTAGACTTATATTTGCATTCAATGACGAAAAACAAATATAT GAAAATGAATTTAGTTTGATGAATGTAAATAATTCAAATTTCACAGTAAGTGCAATAAAGAAAGAAGAAAAAGGAGATGG AATTGTAGTTAGAATCTTCAATGGTATGAAAAATGAGGATGCTAAGGGAAGTCTTAACATCAATAAAAATGTCAATGATG CTTATAGTGCAATGCTCGACGAAATCTATGATAATACTAGCAAGCTTAAAGTAAATACTAAAACTGTAGAGGTAAATTCT TTATCACATTGTAAAGTACAAACAATAGTAATTAAATAA
Upstream 100 bases:
>100_bases ATGAAATAGAGTTAGATATAATGTAAATTAAAAACTTAATTTTAGATAATTGAGAATTGAGTGTACTCTCAATTCTCAAT TAAATTTTGGGAGGATTTTT
Downstream 100 bases:
>100_bases TATAAAATAGCTTATACAAGATTTCAAAATAAATTGCTAGTACTATGTTAATAGTAAAGCCAGATATTATGCTATTTATA AGCTCTGTAACACTAAATAA
Product: alpha-mannosidase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 892; Mature: 892
Protein sequence:
>892_residues MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKEDFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRR LVIGPWYTQTDQLVISGESIIRNLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNGFDQAPIRKNLPDILKKANEIDN ENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHMRIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPH LVIKDIWKLMFENAAHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGFPEVRNEVV EFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYIPKTVYRAKIALSVKDIPPMGYTQLVFELDT KNKCEIETSNCKEIENKYYKITANKNGSLEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLK SNIQEEMILKYSLTIPTSLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRVLFNTEIASKFSIADQQ FGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLEDGQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGR ENLLYRPGRASGEKIIATPDAQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQIY ENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYSAMLDEIYDNTSKLKVNTKTVEVNS LSHCKVQTIVIK
Sequences:
>Translated_892_residues MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKEDFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRR LVIGPWYTQTDQLVISGESIIRNLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNGFDQAPIRKNLPDILKKANEIDN ENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHMRIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPH LVIKDIWKLMFENAAHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGFPEVRNEVV EFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYIPKTVYRAKIALSVKDIPPMGYTQLVFELDT KNKCEIETSNCKEIENKYYKITANKNGSLEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLK SNIQEEMILKYSLTIPTSLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRVLFNTEIASKFSIADQQ FGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLEDGQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGR ENLLYRPGRASGEKIIATPDAQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQIY ENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYSAMLDEIYDNTSKLKVNTKTVEVNS LSHCKVQTIVIK >Mature_892_residues MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKEDFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRR LVIGPWYTQTDQLVISGESIIRNLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNGFDQAPIRKNLPDILKKANEIDN ENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHMRIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPH LVIKDIWKLMFENAAHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGFPEVRNEVV EFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYIPKTVYRAKIALSVKDIPPMGYTQLVFELDT KNKCEIETSNCKEIENKYYKITANKNGSLEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLK SNIQEEMILKYSLTIPTSLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRVLFNTEIASKFSIADQQ FGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLEDGQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGR ENLLYRPGRASGEKIIATPDAQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQIY ENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYSAMLDEIYDNTSKLKVNTKTVEVNS LSHCKVQTIVIK
Specific function: May hydrolyze mannosyl-D-glycerate to mannose-6- phosphate and glycerate [H]
COG id: COG0383
COG function: function code G; Alpha-mannosidase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the glycosyl hydrolase 38 family [H]
Homologues:
Organism=Homo sapiens, GI46852164, Length=346, Percent_Identity=25.7225433526012, Blast_Score=86, Evalue=1e-16, Organism=Escherichia coli, GI1786952, Length=860, Percent_Identity=34.3023255813954, Blast_Score=583, Evalue=1e-167, Organism=Saccharomyces cerevisiae, GI6321282, Length=513, Percent_Identity=21.4424951267057, Blast_Score=69, Evalue=4e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011013 - InterPro: IPR011330 - InterPro: IPR011682 - InterPro: IPR015341 - InterPro: IPR000602 [H]
Pfam domain/function: PF09261 Alpha-mann_mid; PF01074 Glyco_hydro_38; PF07748 Glyco_hydro_38C [H]
EC number: NA
Molecular weight: Translated: 103136; Mature: 103136
Theoretical pI: Translated: 5.43; Mature: 5.43
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKEDFKYFTMDAQASLLDD CCCCEEEEECCCCCCCEEEEEECCCEEEEHHHHHHHHHHHHCCCCCEEEEECCHHHHHHH YLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIRNLYYGIDRCNEFGEPMRV HHHCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCEEE GYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTEFIWKGSDGSKVLAVQIPFGY ECCCCCCCCCCCCCHHHHCCCCCHHHEECCCCCCCCCCCHHEEECCCCCEEEEEEECCEE YYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNGFDQAPIRKNLPDILKKANEIDN EECCCCCCCHHHHHHHHHHHHHHEEEEECCCCEECCCCCCCCCCCCCCHHHHHHHHHCCC ENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHMRIHKSIFSSRSDLKIMNNKLENYI CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH TNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENAAHDSIGSCNSDTTNEDVYTRYKQARD HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCC LSINLLDLHMRLISTQIKNNNEEITLTVFNGFPEVRNEVVEFDTYIPGQDFVIKNKNGKI CEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCCE LNYIIKEKEDITNYILTQTIRLNPSKKIYIPKTVYRAKIALSVKDIPPMGYTQLVFELDT EEHHHHCHHHHHHHHHHEEEEECCCCEEEECHHEEEEEEEEEEECCCCCCCEEEEEEECC KNKCEIETSNCKEIENKYYKITANKNGSLEILDKESNKTYKNQAVIEDNGDDGDSYNYSP CCCEEEECCCHHHHCCCEEEEEECCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCC PRKDIYVSSLDSVSSVEVLKSNIQEEMILKYSLTIPTSLEERAIGKVSVKMPVTMKITLE CCCCEEEECCCCHHHHHHHHHCCHHHEEEEEEEECCCCHHHHCCCEEEEEEEEEEEEEEC PKEQIIKFNVNIKNNQALSHRVRVLFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRD CCCEEEEEEEEECCCCHHHHEEEEEEECCHHHHHCCCHHHCCCCCCCCHHHHHHHHHCCC NYSWQEKPITIEPMQSFVTLEDGQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGR CCCCCCCCEEEECHHHEEEECCCCCCHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCCC ENLLYRPGRASGEKIIATPDAQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYE CCCEECCCCCCCCEEEECCCHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHH YADFLNGRLIFAFNDEKQIYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNED HHHHHCCEEEEEECCCHHHHCCCEEEEEECCCCEEEEEEECCCCCCCEEEEEECCCCCCC AKGSLNINKNVNDAYSAMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK CCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCEEEEEEEC >Mature Secondary Structure MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKEDFKYFTMDAQASLLDD CCCCEEEEECCCCCCCEEEEEECCCEEEEHHHHHHHHHHHHCCCCCEEEEECCHHHHHHH YLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIRNLYYGIDRCNEFGEPMRV HHHCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCEEE GYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTEFIWKGSDGSKVLAVQIPFGY ECCCCCCCCCCCCCHHHHCCCCCHHHEECCCCCCCCCCCHHEEECCCCCEEEEEEECCEE YYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNGFDQAPIRKNLPDILKKANEIDN EECCCCCCCHHHHHHHHHHHHHHEEEEECCCCEECCCCCCCCCCCCCCHHHHHHHHHCCC ENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHMRIHKSIFSSRSDLKIMNNKLENYI CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH TNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENAAHDSIGSCNSDTTNEDVYTRYKQARD HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCC LSINLLDLHMRLISTQIKNNNEEITLTVFNGFPEVRNEVVEFDTYIPGQDFVIKNKNGKI CEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCCE LNYIIKEKEDITNYILTQTIRLNPSKKIYIPKTVYRAKIALSVKDIPPMGYTQLVFELDT EEHHHHCHHHHHHHHHHEEEEECCCCEEEECHHEEEEEEEEEEECCCCCCCEEEEEEECC KNKCEIETSNCKEIENKYYKITANKNGSLEILDKESNKTYKNQAVIEDNGDDGDSYNYSP CCCEEEECCCHHHHCCCEEEEEECCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCC PRKDIYVSSLDSVSSVEVLKSNIQEEMILKYSLTIPTSLEERAIGKVSVKMPVTMKITLE CCCCEEEECCCCHHHHHHHHHCCHHHEEEEEEEECCCCHHHHCCCEEEEEEEEEEEEEEC PKEQIIKFNVNIKNNQALSHRVRVLFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRD CCCEEEEEEEEECCCCHHHHEEEEEEECCHHHHHCCCHHHCCCCCCCCHHHHHHHHHCCC NYSWQEKPITIEPMQSFVTLEDGQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGR CCCCCCCCEEEECHHHEEEECCCCCCHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCCC ENLLYRPGRASGEKIIATPDAQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYE CCCEECCCCCCCCEEEECCCHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHH YADFLNGRLIFAFNDEKQIYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNED HHHHHCCEEEEEECCCHHHHCCCEEEEEECCCCEEEEEEECCCCCCCEEEEEECCCCCCC AKGSLNINKNVNDAYSAMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK CCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCEEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8905232; 9278503; 9063979 [H]