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The map label for this gene is apbE [H]

Identifier: 126700100

GI number: 126700100

Start: 2864141

End: 2865199

Strand: Direct

Name: apbE [H]

Synonym: CD2483

Alternate gene names: 126700100

Gene position: 2864141-2865199 (Clockwise)

Preceding gene: 126700095

Following gene: 126700108

Centisome position: 66.76

GC content: 26.16

Gene sequence:

>1059_bases
ATGAATAAGAAAAAAATCACATTTATTTTTGTGATATTGATTTTAGCATTAATTTTATTTTCATTTTTTAGGAGTTCAAG
CCAGAATACTAAATATAGTAAAACTAGCTACTACCTTGGTACAGTAAACGAAGTTACTGTATTTAATGTAAAAGAATCCA
AAAGTGATAAAATCTTAAATGAATGTGATTCAATTTTAAGATATATTGACAACAAAATGAGCACTCATATACCAGGAAGT
GATGTTTCTAAAATAAATGATAATGCTGGTAAAAAATTTGTCAGAGTTTCTGATGATACATTTTTCGTCGTAAAAGAAGC
TATACAATATTCCAAATTATCAGATGGATATTTTGACATAACAATTGGTCCATTATCAAATTTATGGGCTATTGGAACAG
ATAAAGCTAAAGTTCCAAGTGATTCTGAGATACAAAAACTTCTGCCTCTTATTGATTATAAGAACATCATATTGGATGAA
AAAAATAAATCTATAAAATTAACCAAAGAAAATATGAAAATTGATTTAGGTGCCATAGCTAAAGGATATGCTGCTGATAA
AATTGTAGCCTATTTAAAATCAGAGGATGTAAAAAAAGGTTTAGTAAACTTAGGAGGAAATATATTTACTTTAGAAGATG
GTAAAAATGATAAACCTTTTAAAATAGGCATTCAAGACCCAACTAGTAAAAATGGTGAATCCATAGGAAACATAGAAACT
ACAAATAAGTCTGTTGTTACTTCTGGAATTTATGAAAGATTTATCGAAAAAGACGGAAAAATATATCATCATATGTTAAA
TCCATTTACAGGGTATCCTTTTGAAAACAATTTAAGTAGTGTTACAATAATCTCTGATAAATCTATTAATTGTGATGCCT
TATCCACTTCTACATTTGGACTTGGTCTTGAAAAAGGTATGGATTTAATTAATAAAATTGATAATGTAGATGCTATATTC
ATAACTAAGGATAAGAAAGTATATTTAACTAAGGGTATAAAAGATAATTTTAAACTTACAGATAAATCTTTTTCTATTGA
AAAATTAAATAAACAATAA

Upstream 100 bases:

>100_bases
TGCCTAAAATAAGAAGAATGTCTTTTTTCTTCATTTTTTGTCCTCCTATGAAATTATGTTATAATAAAATAATAACACAA
TTTCATAGGAGGAATATACC

Downstream 100 bases:

>100_bases
GTTTAAATAATAATTATATCTATTATACATACAAAATACATATGAATTTAAATAGTTATCACATGACTAATGCAAATTTA
ATTTTTATATAAAATATGGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNEVTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGS
DVSKINDNAGKKFVRVSDDTFFVVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLEDGKNDKPFKIGIQDPTSKNGESIGNIET
TNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFENNLSSVTIISDKSINCDALSTSTFGLGLEKGMDLINKIDNVDAIF
ITKDKKVYLTKGIKDNFKLTDKSFSIEKLNKQ

Sequences:

>Translated_352_residues
MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNEVTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGS
DVSKINDNAGKKFVRVSDDTFFVVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLEDGKNDKPFKIGIQDPTSKNGESIGNIET
TNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFENNLSSVTIISDKSINCDALSTSTFGLGLEKGMDLINKIDNVDAIF
ITKDKKVYLTKGIKDNFKLTDKSFSIEKLNKQ
>Mature_352_residues
MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNEVTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGS
DVSKINDNAGKKFVRVSDDTFFVVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLEDGKNDKPFKIGIQDPTSKNGESIGNIET
TNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFENNLSSVTIISDKSINCDALSTSTFGLGLEKGMDLINKIDNVDAIF
ITKDKKVYLTKGIKDNFKLTDKSFSIEKLNKQ

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=330, Percent_Identity=26.3636363636364, Blast_Score=138, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 39415; Mature: 39415

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNEVTVFNVKESKSDKILN
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEEECCCCCHHHHH
ECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFFVVKEAIQYSKLSDGYFDI
HHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEEEECCCEEEHHHHHHHHHCCCCCEEEE
TIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDEKNKSIKLTKENMKIDLGAIA
EECCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCEEEEECCCCEEEEHHHH
KGYAADKIVAYLKSEDVKKGLVNLGGNIFTLEDGKNDKPFKIGIQDPTSKNGESIGNIET
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEECCCCCCCCCCCCCCEEC
TNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFENNLSSVTIISDKSINCDALSTSTFG
CCCHHHHHHHHHHHHHCCCCEEHHHCCCCCCCCCCCCCCEEEEEECCCCCCCEECCCCCC
LGLEKGMDLINKIDNVDAIFITKDKKVYLTKGIKDNFKLTDKSFSIEKLNKQ
CCHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCEECCCCCCHHHCCCC
>Mature Secondary Structure
MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNEVTVFNVKESKSDKILN
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEEECCCCCHHHHH
ECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFFVVKEAIQYSKLSDGYFDI
HHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEEEECCCEEEHHHHHHHHHCCCCCEEEE
TIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDEKNKSIKLTKENMKIDLGAIA
EECCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCEEEEECCCCEEEEHHHH
KGYAADKIVAYLKSEDVKKGLVNLGGNIFTLEDGKNDKPFKIGIQDPTSKNGESIGNIET
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEECCCCCCCCCCCCCCEEC
TNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFENNLSSVTIISDKSINCDALSTSTFG
CCCHHHHHHHHHHHHHCCCCEEHHHCCCCCCCCCCCCCCEEEEEECCCCCCCEECCCCCC
LGLEKGMDLINKIDNVDAIFITKDKKVYLTKGIKDNFKLTDKSFSIEKLNKQ
CCHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCEECCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]