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The map label for this gene is bltR [H]

Identifier: 126699657

GI number: 126699657

Start: 2352828

End: 2353637

Strand: Direct

Name: bltR [H]

Synonym: CD2040

Alternate gene names: 126699657

Gene position: 2352828-2353637 (Clockwise)

Preceding gene: 126699645

Following gene: 126699658

Centisome position: 54.84

GC content: 27.28

Gene sequence:

>810_bases
ATGATTAAAAAATTATATAAGACAAGTGAATTTGCAGAATTGTGTGGGGTAAAAAAACATACACTTTACCATTATGATGA
AATTGAATTATTAAAACCGAGTATTACCCATGAAAATGGCTATCGGTATTATACAATTGACCAATTTGAAAAATTTAATA
TTATTTCTGTGCTAAAAAAAGCAGGTACACCTTTAGAAGAAATAAAACAATATCTCAATGATTTAGATACGAATACCTTT
CTTAATGTACTTCACAGAAAGCTAATGGATCTTCAAGAAGAAGTGAAGAAGATTGAAAAAATGTGTTCTATGTTGAGAAA
TGTCATTTCAACAATGGAAATACATCTCAATGTAAACACAGAAAAAATCGAAATTGTAAATTGTGAGGAAGAATATCTGA
TTGCAACTAAAATTCCTGAAGCTGTACTAACAGATGAAAAAACAATGTTACAAGGTATTGGAAATCACTTACAATATTGT
TTATTACATGATTATAATTTTCATGTAGGAGAAATTGTTCTTGAAAAAAATATAAAACAGGGAATTTTTAGAGAGAGCTA
TTATTATAGCCTTATTAAAAATAAAGTAGATGATGAGCGCCTTTTTATTAAACCAAAGGGAAATTATGCAGTTATGTATC
ACCAGGGGAGTTATGACAGTTTATATAAAACTTATCAAAATATGAAAAATCAGTTAGAAGAACAAGGGTATCATATTGTT
GGAAATATTTATGAAGAAGATTTAATTGATTATTTATCAGAACATAACGCCGAAAACTACATTCAAAAAATTTCTATACA
GGTTATTTGA

Upstream 100 bases:

>100_bases
AATTTTCATAATATCTTTTCCTCACATTTCATTGAATATAAAAGCTTTCTATGTTATCCTAAAGTATCTGGTAACCCTAA
AGTCAATAGGAGATTTAAAA

Downstream 100 bases:

>100_bases
AAATATAAAAAGCGTGTATATCTCAAATCACATGAGAAATACACGCCTTTTTTAATATCTCGTATTGTCTATAATAATTT
GCTTAAAATGTCCTTTTTTA

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MIKKLYKTSEFAELCGVKKHTLYHYDEIELLKPSITHENGYRYYTIDQFEKFNIISVLKKAGTPLEEIKQYLNDLDTNTF
LNVLHRKLMDLQEEVKKIEKMCSMLRNVISTMEIHLNVNTEKIEIVNCEEEYLIATKIPEAVLTDEKTMLQGIGNHLQYC
LLHDYNFHVGEIVLEKNIKQGIFRESYYYSLIKNKVDDERLFIKPKGNYAVMYHQGSYDSLYKTYQNMKNQLEEQGYHIV
GNIYEEDLIDYLSEHNAENYIQKISIQVI

Sequences:

>Translated_269_residues
MIKKLYKTSEFAELCGVKKHTLYHYDEIELLKPSITHENGYRYYTIDQFEKFNIISVLKKAGTPLEEIKQYLNDLDTNTF
LNVLHRKLMDLQEEVKKIEKMCSMLRNVISTMEIHLNVNTEKIEIVNCEEEYLIATKIPEAVLTDEKTMLQGIGNHLQYC
LLHDYNFHVGEIVLEKNIKQGIFRESYYYSLIKNKVDDERLFIKPKGNYAVMYHQGSYDSLYKTYQNMKNQLEEQGYHIV
GNIYEEDLIDYLSEHNAENYIQKISIQVI
>Mature_269_residues
MIKKLYKTSEFAELCGVKKHTLYHYDEIELLKPSITHENGYRYYTIDQFEKFNIISVLKKAGTPLEEIKQYLNDLDTNTF
LNVLHRKLMDLQEEVKKIEKMCSMLRNVISTMEIHLNVNTEKIEIVNCEEEYLIATKIPEAVLTDEKTMLQGIGNHLQYC
LLHDYNFHVGEIVLEKNIKQGIFRESYYYSLIKNKVDDERLFIKPKGNYAVMYHQGSYDSLYKTYQNMKNQLEEQGYHIV
GNIYEEDLIDYLSEHNAENYIQKISIQVI

Specific function: Activates transcription of the blt gene in response to structurally dissimilar drugs [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011256
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 31880; Mature: 31880

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKLYKTSEFAELCGVKKHTLYHYDEIELLKPSITHENGYRYYTIDQFEKFNIISVLKK
CCCHHHHHHHHHHHHCCHHHHEEECCCHHEECCCCCCCCCEEEEEECCCCHHHHHHHHHH
AGTPLEEIKQYLNDLDTNTFLNVLHRKLMDLQEEVKKIEKMCSMLRNVISTMEIHLNVNT
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECC
EKIEIVNCEEEYLIATKIPEAVLTDEKTMLQGIGNHLQYCLLHDYNFHVGEIVLEKNIKQ
CEEEEEECCCCEEEEECCCHHHHCCHHHHHHHHHHHHHEHHEECCCCCHHHHHHHHHHHH
GIFRESYYYSLIKNKVDDERLFIKPKGNYAVMYHQGSYDSLYKTYQNMKNQLEEQGYHIV
HHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEE
GNIYEEDLIDYLSEHNAENYIQKISIQVI
EHHHHHHHHHHHHHCCHHHHHHHHEEEEC
>Mature Secondary Structure
MIKKLYKTSEFAELCGVKKHTLYHYDEIELLKPSITHENGYRYYTIDQFEKFNIISVLKK
CCCHHHHHHHHHHHHCCHHHHEEECCCHHEECCCCCCCCCEEEEEECCCCHHHHHHHHHH
AGTPLEEIKQYLNDLDTNTFLNVLHRKLMDLQEEVKKIEKMCSMLRNVISTMEIHLNVNT
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECC
EKIEIVNCEEEYLIATKIPEAVLTDEKTMLQGIGNHLQYCLLHDYNFHVGEIVLEKNIKQ
CEEEEEECCCCEEEEECCCHHHHCCHHHHHHHHHHHHHEHHEECCCCCHHHHHHHHHHHH
GIFRESYYYSLIKNKVDDERLFIKPKGNYAVMYHQGSYDSLYKTYQNMKNQLEEQGYHIV
HHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEE
GNIYEEDLIDYLSEHNAENYIQKISIQVI
EHHHHHHHHHHHHHCCHHHHHHHHEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7608059; 8969508; 9384377 [H]