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The map label for this gene is aroE [H]

Identifier: 126699446

GI number: 126699446

Start: 2126973

End: 2127782

Strand: Direct

Name: aroE [H]

Synonym: CD1837

Alternate gene names: 126699446

Gene position: 2126973-2127782 (Clockwise)

Preceding gene: 126699445

Following gene: 126699447

Centisome position: 49.58

GC content: 28.02

Gene sequence:

>810_bases
ATGAATTTTTTCGGTCTAGTAGGTGAAAAACTCTCTCACAGTGTTTCACCTCAAATCCACAAGAGAGTATTCGAGATATT
GAATATTGAAAGTGCTTATAAAAACTTTGAAATTTCAAAAGAAGATATATCTAAGCTAGACGGTGCTATAAAATTATTAG
GAATACAAGGGGTAAATGTTACTGTACCATATAAGGAGCGTATTATGAAATATCTTGATTTTATATCACCAGAGGCAAAA
CGTATAGGAGCAGTTAATACAATTTTACTCAGAGAAAATATGTTATATGGTTACAATACAGATTACTTTGGTCTTGATAG
TATGTTTAAAATGGCTAATATTGATGTTCAAGGAAAAGTAGCAGTTATATTAGGAACTGGAGGTGCTTCTAAAGCTGCTC
TTACATATTTTATTGATTCTGGTATAGAAAAGCTTTATGTTTCAACTAGAAAAAAGGATGATAAAAAATTATTAAATAGT
AAAGCTATATTAATAGATTATGAAGAACTTAAACATATAAAAGGAGATATAATATTAAATGCTACACCAGTAGGTATGTA
CCCTAATGTAGGAATTTCACCAGTGTCAAAATCTATTATACAAAATTTTGATATATTAATAGATTTAATTTACAATCCTG
GAGAAACAGAGTTTTTAAGAATTGGTAATAGTATGGGTAAAAAAACTTGTGATGGATTATATATGCTGGTGGGGCAAGCA
ATAAAATCTCAGGAAATTTGGCAAGATACTAAAATAGATAATAGTATTTTAGATGTTATATATAATGAACTAAAATTAGA
ATTTTTGTAA

Upstream 100 bases:

>100_bases
CATAATACAGCATATTTTAAATTTATGGGAGTATATAAAAATAAAACTGAATAGATAAGATAAATTTTTATTTAATTTAT
AATTATTAGGAGGTGTAAGT

Downstream 100 bases:

>100_bases
GGGAGATTGTTATGATAAATAAAACAAAAGAAAAATTGATATTAATAGGTATGCCAGGTAGTGGAAAAACTACAATTGGT
AAACTTTTGGCCAAAGAATA

Product: shikimate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDISKLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAK
RIGAVNTILLRENMLYGYNTDYFGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEFLRIGNSMGKKTCDGLYMLVGQA
IKSQEIWQDTKIDNSILDVIYNELKLEFL

Sequences:

>Translated_269_residues
MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDISKLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAK
RIGAVNTILLRENMLYGYNTDYFGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEFLRIGNSMGKKTCDGLYMLVGQA
IKSQEIWQDTKIDNSILDVIYNELKLEFL
>Mature_269_residues
MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDISKLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAK
RIGAVNTILLRENMLYGYNTDYFGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEFLRIGNSMGKKTCDGLYMLVGQA
IKSQEIWQDTKIDNSILDVIYNELKLEFL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=260, Percent_Identity=29.6153846153846, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789675, Length=260, Percent_Identity=31.1538461538462, Blast_Score=100, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6320332, Length=159, Percent_Identity=34.5911949685535, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30209; Mature: 30209

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDISKLDGAIKLLGIQGVNV
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEEEECCCEE
TVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDYFGLDSMFKMANIDVQGKV
EECHHHHHHHHHHHCCCCHHHHCHHHEEEEECCEEECCCCCCCCHHHHHHHHCCCCCCEE
AVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNSKAILIDYEELKHIKGDIILN
EEEEECCCCCHHHHHHHHHHCHHHHHHHHCCCHHHHHHCCCEEEEEHHHHHHCCCCEEEE
ATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEFLRIGNSMGKKTCDGLYMLVGQA
CCCCCCCCCCCCCHHHHHHHHHHHHEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHH
IKSQEIWQDTKIDNSILDVIYNELKLEFL
HHHHHHHHHCCCCHHHHHHHHHHHHEECC
>Mature Secondary Structure
MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDISKLDGAIKLLGIQGVNV
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEEEECCCEE
TVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDYFGLDSMFKMANIDVQGKV
EECHHHHHHHHHHHCCCCHHHHCHHHEEEEECCEEECCCCCCCCHHHHHHHHCCCCCCEE
AVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNSKAILIDYEELKHIKGDIILN
EEEEECCCCCHHHHHHHHHHCHHHHHHHHCCCHHHHHHCCCEEEEEHHHHHHCCCCEEEE
ATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEFLRIGNSMGKKTCDGLYMLVGQA
CCCCCCCCCCCCCHHHHHHHHHHHHEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHH
IKSQEIWQDTKIDNSILDVIYNELKLEFL
HHHHHHHHHCCCCHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA