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The map label for this gene is aroF [H]

Identifier: 126699441

GI number: 126699441

Start: 2121258

End: 2122271

Strand: Direct

Name: aroF [H]

Synonym: CD1832

Alternate gene names: 126699441

Gene position: 2121258-2122271 (Clockwise)

Preceding gene: 126699440

Following gene: 126699442

Centisome position: 49.44

GC content: 32.54

Gene sequence:

>1014_bases
ATGATAGTAGTATTAAAAATGGGAGCAGATAAAAATGAAGTTAAAAAATTAATTGAGGCTATTGGGAGAGAAGGAGTAGA
AGTTAATCCCATAGATGGAACAGAATTAACTGTTTTAGGTTTAGTTGGAGATACTAGTAAAATAGATGCCAAAAGAATAG
AAGCAAATAAGGTAGTTGAAAAAGTTATGCATGTGGTAGAGCCTTTTAAAAAGGCCAATAGAAAATTTCATCCAGAACCT
TCAATCATAAATGTTAATGGAATGGAAATTGGTTCAAAGAAAATTGCTATGATAGCTGGGCCTTGTTCTGTTGAAACAGA
AGACCAAATAGTATCTATAGCTAAAGATGTGAAAAAATCAGGTGCAGGATTTTTGAGAGGTGGAGCATTCAAACCAAGAA
CATCACCATACGCTTTCCAAGGATTGAAATATGATGGATTGGATTTATTAAAAAAAGCAAAAGAAAAAACAGGGCTTCCT
ATAGTTACAGAAATAATGTCAACACAAGATATAGATATATTTGAAGAAAATGTAGATGTAATTCAAGTTGGAGCTAGAAA
CATGCAAAACTTTGATTTATTAAAAGAATTAGGTAAAACAAATAAAACAATACTTTTAAAAAGAGGATTATCTGCTACAA
TTGAAGAGTGGCTAATGTCAGCAGAGTATATAATGGCTGGAGGAAATGAAAATGTAGTTCTTTGTGAAAGAGGTATAAGA
ACTTTTGAAACATATACTAGAAATACTTTGGATTTAAGTGCAATTTTAGCTGTGAAGAAACTTAGTCATTTACCAGTTAT
AGTTGACCCAAGTCATGCAGCAGGTAAATCATGGATGGTTGACTCTTTATCTAAGGCAGCAATTGCAGTTGGAGCAGATG
GTCTAATAATCGAAGTTCATAATGACCCAGCACATGCACTTTGTGATGGAAAACAATCGATTAAGCCAAATGAATATGAT
GAATTGATAAGTGAATTAAAGACTATCGCATCAGCAGTTGGTAGAGAAATATAA

Upstream 100 bases:

>100_bases
TATATAAGATTTAGTGCTTGATAGATTATTTTAGAGAACTCATTAGTGAGTTCTCTTTTTTATTTTAAATATAAAATTAT
AATATTGGGAGGTAGTAAAA

Downstream 100 bases:

>100_bases
TCTATAAAAGGATGGTTAAACGTGGAAGAAAAACTATTAGTAAATTTAAAAGAAAATAGCTACAATATATTTATTAAAAA
AAATATACTAAAGAATATAG

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGDTSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEP
SIINVNGMEIGSKKIAMIAGPCSVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWLMSAEYIMAGGNENVVLCERGIR
TFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGKSWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYD
ELISELKTIASAVGREI

Sequences:

>Translated_337_residues
MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGDTSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEP
SIINVNGMEIGSKKIAMIAGPCSVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWLMSAEYIMAGGNENVVLCERGIR
TFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGKSWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYD
ELISELKTIASAVGREI
>Mature_337_residues
MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGDTSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEP
SIINVNGMEIGSKKIAMIAGPCSVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWLMSAEYIMAGGNENVVLCERGIR
TFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGKSWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYD
ELISELKTIASAVGREI

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=210, Percent_Identity=29.0476190476191, Blast_Score=92, Evalue=6e-20,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 36691; Mature: 36691

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGDTSKIDAKRIEANKVVE
CEEEEECCCCHHHHHHHHHHHCCCCCEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
KVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPCSVETEDQIVSIAKDVKKS
HHHHHHHHHHHCCCCCCCCCCEEEECCCEECCCEEEEEECCCCCCCHHHHHHHHHHHHHC
GAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLPIVTEIMSTQDIDIFEENVDV
CCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCHHHHCCCCE
IQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWLMSAEYIMAGGNENVVLCERGIR
EEECCCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHEEECCCCCEEEECCCCH
TFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGKSWMVDSLSKAAIAVGADGLIIEVH
HHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHEEECCCEEEEEEC
NDPAHALCDGKQSIKPNEYDELISELKTIASAVGREI
CCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGDTSKIDAKRIEANKVVE
CEEEEECCCCHHHHHHHHHHHCCCCCEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
KVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPCSVETEDQIVSIAKDVKKS
HHHHHHHHHHHCCCCCCCCCCEEEECCCEECCCEEEEEECCCCCCCHHHHHHHHHHHHHC
GAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLPIVTEIMSTQDIDIFEENVDV
CCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCHHHHCCCCE
IQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWLMSAEYIMAGGNENVVLCERGIR
EEECCCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHEEECCCCCEEEECCCCH
TFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGKSWMVDSLSKAAIAVGADGLIIEVH
HHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHEEECCCEEEEEEC
NDPAHALCDGKQSIKPNEYDELISELKTIASAVGREI
CCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]