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The map label for this gene is scrK [H]

Identifier: 126699415

GI number: 126699415

Start: 2089154

End: 2090125

Strand: Direct

Name: scrK [H]

Synonym: CD1806

Alternate gene names: 126699415

Gene position: 2089154-2090125 (Clockwise)

Preceding gene: 126699414

Following gene: 126699417

Centisome position: 48.7

GC content: 28.19

Gene sequence:

>972_bases
ATGAAAAAAGTAATTAGTATAGGAGAAGCTTTAATAGACTTTATACCTAATCAAAATGGTGGTAAATTAAAAAATGTATC
AGAATTTAGAAGAGTAGCAGGAGGAGCTCCAGCAAATGTTAGTGCTGTTGTAGCAAAGCTTGGAGGAAAATCAAGTTTTA
TATCTAAGTTAGGAAAAGATGCATTTGGTGATTATATAATAGATGTATTAAATGAAGTAAATGTAAATACTGATTATGTA
TTGAGAACAAGTAAAGCAAATACAGGACTTGCTTTTGTATCATTAAAAGAAGATGGTAATCGTGATTTCTCATTTTATAG
AAATCCAAGTGCAGATATGCTTTTAGAAGCTGATGAAGTTAAAAAAGAGTGGTTTAATAATTGTCATATCCTACATTTTT
GTTCAGTAGATTTAATAGATAGTCCAATGAAATTAGCACATAAAAAAGCAATAGAATACGCACTTGAAAGTAATAGTATA
ATAAGCTTTGACCCTAATATAAGATTACCTTTATGGGATAGTGAGCAATCTTGTAAAAAGGCAATATCAGAATTTTTACC
TTTTGCTCATATTGTTAAGATATCTGATGAAGAATTAGAATTTATAACAGGAGAAAATGATATAGAAAAATCATTACATA
AACTCTTTGTGGGGAATGTTGAACTAGTATTATATACAAAAGGAAAAGATGGAGTAGATGCATACACTAAAAAAGTAAAA
GGTATGTGTAAAGGGGTTAAAGTAAATGCAATAGATACAACCGGAGCAGGAGATTCTTATATAGGTTCATTTTTATACAC
CTTATTGTATAAACAAATAACATTGAATGATATAAAAGAAATGAAACAAGAAACGTTAAATGAGTATTTAGAATTTTCTA
ATTATTATGCAGCTCGTAGTACAACTATTAAAGGTGCGATAAGTTCATATGCAACAAAGGAAGAAATAACTGAATTTATA
AAAAATTTATAG

Upstream 100 bases:

>100_bases
ATAAGGGTTTATAGTGATAAAATAGTAGAGTATGAGTATACTAAATTTAAATTAAAGCAAGGTATTGAATTATAAAAACA
CATTATAAGGGGTAGAAAAG

Downstream 100 bases:

>100_bases
TAGGAATGAGTAATAGGTTTTGAAGGAAGTAACATGTAAAGAGTTTTTAAGGATGTTTACTATGAAAATAGCAATAAAGA
GGCTGTCTCAAAATAGAGAT

Product: fructokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVVAKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYV
LRTSKANTGLAFVSLKEDGNRDFSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVGNVELVLYTKGKDGVDAYTKKVK
GMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLNDIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFI
KNL

Sequences:

>Translated_323_residues
MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVVAKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYV
LRTSKANTGLAFVSLKEDGNRDFSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVGNVELVLYTKGKDGVDAYTKKVK
GMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLNDIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFI
KNL
>Mature_323_residues
MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVVAKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYV
LRTSKANTGLAFVSLKEDGNRDFSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVGNVELVLYTKGKDGVDAYTKKVK
GMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLNDIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFI
KNL

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=293, Percent_Identity=24.9146757679181, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87081971, Length=334, Percent_Identity=26.3473053892216, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082281, Length=287, Percent_Identity=24.390243902439, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790193, Length=292, Percent_Identity=24.6575342465753, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082343, Length=327, Percent_Identity=24.7706422018349, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=303, Percent_Identity=26.4026402640264, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: NA

Molecular weight: Translated: 35999; Mature: 35999

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVVAKLGGKSSFISKLGKD
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHCHH
AFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRDFSFYRNPSADMLLEADEV
HHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCEEECCCHHHEEEHHHH
KKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSIISFDPNIRLPLWDSEQSCKK
HHHHHCCCEEEEEECHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCHHHHHH
AISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVGNVELVLYTKGKDGVDAYTKKVK
HHHHHCCHHHEEEECCCCEEEECCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHH
GMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLNDIKEMKQETLNEYLEFSNYYAARS
HHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTIKGAISSYATKEEITEFIKNL
HHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVVAKLGGKSSFISKLGKD
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHCHH
AFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRDFSFYRNPSADMLLEADEV
HHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCEEECCCHHHEEEHHHH
KKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSIISFDPNIRLPLWDSEQSCKK
HHHHHCCCEEEEEECHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCHHHHHH
AISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVGNVELVLYTKGKDGVDAYTKKVK
HHHHHCCHHHEEEECCCCEEEECCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHH
GMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLNDIKEMKQETLNEYLEFSNYYAARS
HHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTIKGAISSYATKEEITEFIKNL
HHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9455482; 9384377 [H]