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The map label for this gene is scrR [H]

Identifier: 126699413

GI number: 126699413

Start: 2086324

End: 2087310

Strand: Direct

Name: scrR [H]

Synonym: CD1804

Alternate gene names: 126699413

Gene position: 2086324-2087310 (Clockwise)

Preceding gene: 126699412

Following gene: 126699414

Centisome position: 48.63

GC content: 27.15

Gene sequence:

>987_bases
ATGAAAAAAATAACAATAAATGATATTGCTAACTTGGCAGGAGTATCTAAAAGTACTGTATCAAGATATCTAAATAATAA
AGATATCAGTGATTCTACTAAAGAGAAAATAAAGACAATAATAGATGAATATGGATATGAGCCGAATGCATTTGCTCAAA
GTTTGAGAGCTAAAAAAACATACTTTATTGGTATTATAACACCGTGTTTAGATTCTTTTGTAAAATCTAAAATTATGATG
GCAATAGATGAAGAACTCAAAGAATTAAAATATACATCACTAATTATTAATACTAATAGAAAAATAAGGTCAGAAATAGA
TAGTATATCAAAATTAGCTAGTCTAAAAGTTGATGGAATAATACTAATTGGTACCGAAATAACTAAAGAACATAAGAATG
AAATTGAAAAGTTAGATATACCGATAGTTGTAGTTGGACAAAAAGTTGATGGTATCAATAGTATAGTGAATGATGATTAT
GGAGCAGGATATAAAATGGGTCAATATATTGCTAATAAAGGTTACAAAAACATTGTATATTTAGGTGTTGATGAAAGTGA
TATATCAGTTGGTTTAAATAGAAAAAATGGAGTACTTAATGGGTTAAAAGATAAAGGGTATGATGCAAAAGTATTTTATA
CTGACTTTGACCAAGAAACGTCTATACAAAGAAGTGGAGAAATGCTAGAAAGTGAAAATCCAGATATAATAATATGTGCA
ACTGATAATATAGCAATAGCAACAATGAAAGAAATCAATAAGAGAGGTAAAAGTATACCACAAGATATATCTGTAGCTGG
ATTTGGGGGATATGATGTATTGTCTATTATAAGCCCTAAACTTACAACAATAAAGTTTGAAAATAAAAATGCAGGTAAAG
TAGCAGCAAATACGATAGTAAACTTAATACAAGAAAGAAAAGAACCACTATTAAAGGAGATTAAATTTGAATTAATAGAA
GGTGAAAGTACAATAAATAAAAATTAA

Upstream 100 bases:

>100_bases
AGTAGTATATAAAAAGTATTGACTGGACAAATAACTATATTTTATTTTAAATATATAATATAATGTAATAAAATATATCA
AATGTAGAAGGTGATAACCT

Downstream 100 bases:

>100_bases
GATACACATTACATATATTAGTAATGTGTATTTTTTTACTAAAAAAACTATAATTCTAAAAATTAGGAAAACTTTTTTGA
AAGAAATATTGCATCTGAAA

Product: sucrose operon repressor

Products: NA

Alternate protein names: Scr operon regulatory protein [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEYGYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMM
AIDEELKELKYTSLIINTNRKIRSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQETSIQRSGEMLESENPDIIICA
TDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSIISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIE
GESTINKN

Sequences:

>Translated_328_residues
MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEYGYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMM
AIDEELKELKYTSLIINTNRKIRSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQETSIQRSGEMLESENPDIIICA
TDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSIISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIE
GESTINKN
>Mature_328_residues
MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEYGYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMM
AIDEELKELKYTSLIINTNRKIRSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQETSIQRSGEMLESENPDIIICA
TDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSIISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIE
GESTINKN

Specific function: Negative regulator of scrB expression [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790689, Length=309, Percent_Identity=25.5663430420712, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI48994940, Length=340, Percent_Identity=26.7647058823529, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787948, Length=330, Percent_Identity=25.4545454545455, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1786268, Length=324, Percent_Identity=26.2345679012346, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790715, Length=314, Percent_Identity=28.0254777070064, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790194, Length=322, Percent_Identity=24.5341614906832, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787580, Length=322, Percent_Identity=27.0186335403727, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790369, Length=310, Percent_Identity=24.5161290322581, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786540, Length=338, Percent_Identity=26.3313609467456, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789202, Length=294, Percent_Identity=25.5102040816327, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1789068, Length=291, Percent_Identity=24.3986254295533, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787906, Length=287, Percent_Identity=25.7839721254355, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788474, Length=304, Percent_Identity=25, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36423; Mature: 36423

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEYGYEPNAFAQSLRAKKT
CCEEEHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCE
YFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKIRSEIDSISKLASLKVDGI
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHCCCCCE
ILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDYGAGYKMGQYIANKGYKNIVY
EEECCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCEEEE
LGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQETSIQRSGEMLESENPDIIICA
EECCCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEE
TDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSIISPKLTTIKFENKNAGKVAANTIV
CCCEEEHHHHHHHHHCCCCCCCCEEECCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHH
NLIQERKEPLLKEIKFELIEGESTINKN
HHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEYGYEPNAFAQSLRAKKT
CCEEEHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCE
YFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKIRSEIDSISKLASLKVDGI
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHCCCCCE
ILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDYGAGYKMGQYIANKGYKNIVY
EEECCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCEEEE
LGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQETSIQRSGEMLESENPDIIICA
EECCCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEE
TDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSIISPKLTTIKFENKNAGKVAANTIV
CCCEEEHHHHHHHHHCCCCCCCCEEECCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHH
NLIQERKEPLLKEIKFELIEGESTINKN
HHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550467 [H]