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The map label for this gene is mta [H]

Identifier: 126699396

GI number: 126699396

Start: 2069707

End: 2070870

Strand: Direct

Name: mta [H]

Synonym: CD1787

Alternate gene names: 126699396

Gene position: 2069707-2070870 (Clockwise)

Preceding gene: 126699395

Following gene: 126699402

Centisome position: 48.24

GC content: 26.55

Gene sequence:

>1164_bases
ATGAGAACAGTGAAACAAGTTTCTGATTTAACTGGAATAAGTGTGAGGGCATTACATTATTATGATGAAATAGGTCTTTT
AAAACCAAATAAAATTACAGATGCAGGATATAGACTTTATGATGATGAATCTATTAAAACTCTTCAACAAATTTTATTTT
TTAAGGAGATTGATATTCCTTTAAGAGAGGTTAAGGAAATAATGTCAAGCCAATATTTTGATAAGGTTGAAGCTCTAAAA
AATCAAAAAAAATTACTTATTTTAAAACGAAAGAGACTGGATGAATTGATAGAGCTTATAAATCAAACTCTAAGAGGAGA
AGGAAATATTGATTTTAAAGAGTTTGATATGAGCGAGTATTTTGATGTTTTAGAAGAATTTAAAAGAGAGCATAGGAATA
AGGTAATTAAAATTTATGGTAGTGTAGAAAAATACAATGAATATATAGAAAGAGTTAAGTCTAATGAAGAGAAAATTGCT
AAAATGGCTATAAAACAATATGGAACTATTGAGAAGTTTGCTAAAGCTATAAAAACAAATTTTAGCAGTGATATATTGAA
TTTAGGAGAAAAATTTGATAGATATAAAAATGATTGTTTAAAAGAAAAACATCCAAAATTAAAAGAATTATATAGAAAGC
TTGTAGAAGATTTAAGTAGGAATCATTCTTCAACAGACCTTCAAGAAATAGCAAAAGAGATAACAGATATATCTAAAAAA
GATTATGAAATTTTCTCTATGGATACTGGTGATGACAACTGGTATTATATGGTTCAAAATTATCTAGTAAATCCTATGTG
GATAGAAGAAGTAGATAAAAAGTATGGAAGTGGAGCAGGTAAGTTTATTGGACAAGTACTAAAGACTTATCTAAGAGATA
GAAAACCAAAGATAAATACATTGTATGAAAAACTTGTAGAAGATTTGAGTAGAGATTGTTCTTCAAGGGAAGTTCAAAGC
ATTGTTGAAGAAATAGACAATGAAATGAAAAGAAGTAATGAATTTTATAAAATAGACAATGGTGAAAGATACTTTGATTA
TATGTCAGAGCTTTATTTACAAGATTCTAACTATATAAAAGTAACTGATAAGAATTATGGTGATGGTGCATCTAAGTTTA
TTGGAGAAGCTTTTAAGATTTATTTTGATAATAATAATTGTTGA

Upstream 100 bases:

>100_bases
ATTGTTGACCCTAACATTACGTAATAGTGTAATATGAAAATATAGCTTGAATATATTAGTAGGTATTGATGGCTGTAAAA
TTAAAATTTGAGGTGTGGAT

Downstream 100 bases:

>100_bases
AAATTTGGAAGTAAAAAATATGTAAGTTTTATAAAAGCACAAAAATAAGGATGTAGATTAGCTCCATCTATATCCTTATT
TAAAGTTATTAAAATATATA

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: Multidrug transporter activation protein [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDESIKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALK
NQKKLLILKRKRLDELIELINQTLRGEGNIDFKEFDMSEYFDVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDLSRNHSSTDLQEIAKEITDISKK
DYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYGSGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQS
IVEEIDNEMKRSNEFYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC

Sequences:

>Translated_387_residues
MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDESIKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALK
NQKKLLILKRKRLDELIELINQTLRGEGNIDFKEFDMSEYFDVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDLSRNHSSTDLQEIAKEITDISKK
DYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYGSGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQS
IVEEIDNEMKRSNEFYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC
>Mature_387_residues
MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDESIKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALK
NQKKLLILKRKRLDELIELINQTLRGEGNIDFKEFDMSEYFDVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDLSRNHSSTDLQEIAKEITDISKK
DYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYGSGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQS
IVEEIDNEMKRSNEFYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC

Specific function: Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself, ydfK and ymfE [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR012925
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; PF07739 TipAS [H]

EC number: NA

Molecular weight: Translated: 45941; Mature: 45941

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDESIKTLQQILFFKEIDIP
CCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCC
LREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQTLRGEGNIDFKEFDMSEY
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHH
FDVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIAKMAIKQYGTIEKFAKAIKTN
HHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCC
FSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDLSRNHSSTDLQEIAKEITDISKK
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
DYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYGSGAGKFIGQVLKTYLRDRKPKINT
CCEEEEECCCCCCCEEHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHH
LYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNEFYKIDNGERYFDYMSELYLQDSNYIK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCCCEEE
VTDKNYGDGASKFIGEAFKIYFDNNNC
EECCCCCCHHHHHHHHHHEEEECCCCC
>Mature Secondary Structure
MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDESIKTLQQILFFKEIDIP
CCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCC
LREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQTLRGEGNIDFKEFDMSEY
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHH
FDVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIAKMAIKQYGTIEKFAKAIKTN
HHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCC
FSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDLSRNHSSTDLQEIAKEITDISKK
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
DYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYGSGAGKFIGQVLKTYLRDRKPKINT
CCEEEEECCCCCCCEEHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHH
LYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNEFYKIDNGERYFDYMSELYLQDSNYIK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCCCEEE
VTDKNYGDGASKFIGEAFKIYFDNNNC
EECCCCCCHHHHHHHHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9150240; 9384377 [H]