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The map label for this gene is trxB1 [H]

Identifier: 126699297

GI number: 126699297

Start: 1963575

End: 1964462

Strand: Direct

Name: trxB1 [H]

Synonym: CD1691

Alternate gene names: 126699297

Gene position: 1963575-1964462 (Clockwise)

Preceding gene: 126699296

Following gene: 126699298

Centisome position: 45.77

GC content: 31.19

Gene sequence:

>888_bases
GTGAGTATTATGAGATATGATATAGCTATAATCGGCAGTGGTCCAGCTGGATTGTCTGCTGCTATAAATGCAAAAATAAG
AAATAAAACAATTATCATGTTTGGTAATGATAATTTAAGTAATAAGCTTGTTAAAGCTCCTTCAATAGATAATTATTTAG
GTTTTTATGATATAAGTGGTGATGAATTAAAAGACAAGTTTAAATCACATATAGATAGTATGGATATTTCAATTGAAAAT
AAAAGAATAAATAATATTTATGCTATGGGAGAATACTTTACAATAATGTCTGGAAATGATATGTATGAAGCTACTACTGT
AATCCTTGCAACTGGGGTAGAGTATACTAGACCAATCAAGGGTGAAGAAGAATTTCTAGGAAGAGGTGTGGGCTACTGTG
CTACATGTGATGCACCACTTTATAGAAATAAAAAGGTAGCAGTTATAGGATATAATGAAGAATCTAAAGAAGAAGCAAAT
TTTTTAAGTGAACTCACTTCAAAGACTTATTTTATACCTATGTACAAAAAAGATAATCTTATGAGAAGTTCAGATAACCT
AGATGATTCTATTGAAGTTATACATGACAGACCAGTACAGATAGATGGAGATAAACTTGTAAACAAAGTATCTTTTAAAG
AAAACCACATTGAAGTTGATGGAGTATTCGTTATAAAAGATAGTACAGCTCCAAGTGCATTGGTTCCTGGAATAGAGATT
GATGGCATTCATATTAAAGTTGACAATAATATGAAGACTAGTATAGATGGATGCTTTGCTGCTGGAGATTGTGTTGGAAA
ACCCTATTCTTATATAAAAGCAGCTGGTCAAGGGCAAATAGCAGCTTTAAATGCTGTTTACTATTTAGATAAATTAAAGA
GGGCTTAA

Upstream 100 bases:

>100_bases
ATGATTATATTTAAAGATGGAAAACCAGTAGAAACTTTAATTGGATTCATGCCAAAGAACAAAATTGAAATGCAAGTAAA
ATCATATTTATAAAAAATGG

Downstream 100 bases:

>100_bases
TATTTATATTGATTAACTTTTTAAAGATATTTATAAAAAACTGTCTTGAAATAATTTTATTATTTCAAGACAGTTTTTTA
TTTTTAAGTTATTAATAAAA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MSIMRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAPSIDNYLGFYDISGDELKDKFKSHIDSMDISIEN
KRINNIYAMGEYFTIMSGNDMYEATTVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEAN
FLSELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDGVFVIKDSTAPSALVPGIEI
DGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQIAALNAVYYLDKLKRA

Sequences:

>Translated_295_residues
MSIMRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAPSIDNYLGFYDISGDELKDKFKSHIDSMDISIEN
KRINNIYAMGEYFTIMSGNDMYEATTVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEAN
FLSELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDGVFVIKDSTAPSALVPGIEI
DGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQIAALNAVYYLDKLKRA
>Mature_294_residues
SIMRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAPSIDNYLGFYDISGDELKDKFKSHIDSMDISIENK
RINNIYAMGEYFTIMSGNDMYEATTVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANF
LSELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDGVFVIKDSTAPSALVPGIEID
GIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQIAALNAVYYLDKLKRA

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=314, Percent_Identity=31.5286624203822, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI87081763, Length=280, Percent_Identity=29.2857142857143, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320560, Length=316, Percent_Identity=31.9620253164557, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6321898, Length=319, Percent_Identity=31.3479623824451, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 32600; Mature: 32468

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIMRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAPSIDNYLGFYDISG
CCEEEEEEEEEECCCCCCEEEEEEEECCEEEEEECCCCCCCCEEECCCCCCCEEEEECCC
DELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEATTVILATGVEYTRPIK
HHHHHHHHHHHCCCCEEEECCEECEEEEECEEEEEEECCCCCEEEEEEEEECCCCCCCCC
GEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLSELTSKTYFIPMYKKDNL
CCHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCCC
MRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDGVFVIKDSTAPSALVPGIEI
CCCCCCCCCCEEEEECCCCEECHHHHHHEECCCCCEEEEEEEEEEECCCCCCCCCCCEEE
DGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQIAALNAVYYLDKLKRA
CEEEEEECCCCEECCCCEEECCCCCCCCHHHHEECCCCCEEEHHHHHHHHHHHCC
>Mature Secondary Structure 
SIMRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAPSIDNYLGFYDISG
CEEEEEEEEEECCCCCCEEEEEEEECCEEEEEECCCCCCCCEEECCCCCCCEEEEECCC
DELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEATTVILATGVEYTRPIK
HHHHHHHHHHHCCCCEEEECCEECEEEEECEEEEEEECCCCCEEEEEEEEECCCCCCCCC
GEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLSELTSKTYFIPMYKKDNL
CCHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCCC
MRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDGVFVIKDSTAPSALVPGIEI
CCCCCCCCCCEEEEECCCCEECHHHHHHEECCCCCEEEEEEEEEEECCCCCCCCCCCEEE
DGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQIAALNAVYYLDKLKRA
CEEEEEECCCCEECCCCEEECCCCCCCCHHHHEECCCCCEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA