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The map label for this gene is yvrH [H]

Identifier: 126699276

GI number: 126699276

Start: 1947076

End: 1947801

Strand: Direct

Name: yvrH [H]

Synonym: CD1671

Alternate gene names: 126699276

Gene position: 1947076-1947801 (Clockwise)

Preceding gene: 126699275

Following gene: 126699277

Centisome position: 45.38

GC content: 28.1

Gene sequence:

>726_bases
ATGGAAAATCGTGTTTTAATAATAGATGATGAAGTAGAAATATTGAAGCTTTTAGAAACTGTCCTAAAAAAAGAGGGTCT
TAATAATATATATACTGCAAAAACTAAAAAAGAAGGATTAGAATTATTTAAAAGTATTAATCCTGATTTGATTGTATTGG
ATATTATGTTACCAGATGGCGAAGGTTATGATATTTGTAAAGAAATAAGAAAAACCTCCAATTCTCCAATAATATTTTTA
TCAGCTAAAACCGAAGAATTAGATAAGTTACTTGGACTAGCGATTGGAGGAGATGATTATGTTACAAAACCTTTTAGCCC
TAAGGAAGTGGCTTTTAGAGTTAAAGCGCATTTGAGAAGATTAAGTTATTTTAGTGATGCTCAAAACGAAAGTAAAAATC
TAAATAATAATGAAGAAAAAATTATATCATTTGGCCCATATATATTAAATGAAAGTAGGGCAGAACTTATAAAAGATGGA
AAATCTATAGGACTGTCTGCAAAGGAACTAAAAATCCTATCTTTATTTGCACATAATCAAAATCAAATTATAAGTAAAGA
AAAACTATGGGATAAAGTGTGGGGAGAAGATTATGTTGGATTTGACAATACTATAATGGTTCATATAAGAAAAATTAGGG
AAAAATTAGAGGATAATCCTTCAAAACCTGAATATATTCTGACAATAAAAGGTCTTGGATATAAATTAGCAGTAAAGGAA
GATTAG

Upstream 100 bases:

>100_bases
AGTAATTTTATTTATATTTTAGTTTAATTAAAAATAAGATAAATGAATTTTAGATAAAATATATGCTAATATATATGTAA
ATTATTACAGGAGGTTGTTT

Downstream 100 bases:

>100_bases
AATATGAAGTGGAAGATTACTAGAAATTTTATATTTACAATTGTGTTTGTAGCTATATCAGTAGTAATTATAAATATCAT
ATCTATATTGTATGTGATTT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFKSINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFL
SAKTEELDKLLGLAIGGDDYVTKPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLEDNPSKPEYILTIKGLGYKLAVKE
D

Sequences:

>Translated_241_residues
MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFKSINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFL
SAKTEELDKLLGLAIGGDDYVTKPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLEDNPSKPEYILTIKGLGYKLAVKE
D
>Mature_241_residues
MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFKSINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFL
SAKTEELDKLLGLAIGGDDYVTKPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLEDNPSKPEYILTIKGLGYKLAVKE
D

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=34.051724137931, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=34.8936170212766, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=30.1724137931034, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=35.7758620689655, Blast_Score=140, Evalue=5e-35,
Organism=Escherichia coli, GI1786599, Length=242, Percent_Identity=30.9917355371901, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790860, Length=236, Percent_Identity=32.6271186440678, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=31.1965811965812, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1787229, Length=241, Percent_Identity=31.9502074688797, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082012, Length=238, Percent_Identity=31.0924369747899, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1786784, Length=239, Percent_Identity=29.2887029288703, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1790552, Length=241, Percent_Identity=29.4605809128631, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789402, Length=237, Percent_Identity=29.535864978903, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI145693140, Length=242, Percent_Identity=26.4462809917355, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=29.3103448275862, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788550, Length=173, Percent_Identity=30.0578034682081, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27500; Mature: 27500

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFKSINPDLIVLDIMLPDG
CCCCEEEECCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCCCEEEEEEEECCC
EGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVTKPFSPKEVAFRVKAHLRR
CCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHH
LSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDGKSIGLSAKELKILSLFAHNQ
HHHHHHCCCCCCCCCCCCHHEEEECCHHHCCHHHHHHHCCHHCCCCHHHHHEEHEEECCC
NQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLEDNPSKPEYILTIKGLGYKLAVKE
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEC
D
C
>Mature Secondary Structure
MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFKSINPDLIVLDIMLPDG
CCCCEEEECCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCCCEEEEEEEECCC
EGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVTKPFSPKEVAFRVKAHLRR
CCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHH
LSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDGKSIGLSAKELKILSLFAHNQ
HHHHHHCCCCCCCCCCCCHHEEEECCHHHCCHHHHHHHCCHHCCCCHHHHHEEHEEECCC
NQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLEDNPSKPEYILTIKGLGYKLAVKE
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]