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The map label for this gene is yvrG [H]

Identifier: 126699277

GI number: 126699277

Start: 1947805

End: 1949208

Strand: Direct

Name: yvrG [H]

Synonym: CD1672

Alternate gene names: 126699277

Gene position: 1947805-1949208 (Clockwise)

Preceding gene: 126699276

Following gene: 126699278

Centisome position: 45.4

GC content: 24.86

Gene sequence:

>1404_bases
ATGAAGTGGAAGATTACTAGAAATTTTATATTTACAATTGTGTTTGTAGCTATATCAGTAGTAATTATAAATATCATATC
TATATTGTATGTGATTTCAACTAATAGTTTTTTTAAAGTTGTAGATTCTGGAAATAATCCTGAAGAATTTGCACGTTCTT
TTGAAAAAGATTTATATGAAAAAGATGGAGAATTTAAACTATCTAAGATTGGAGCTGAAAAATTAGAAAAATCAAATTCC
TGGATACAGGTTTTAAATGATTTAGGAGAGGAAGTTTATGGAGTAAATGTGCCAAAGGATACTCCCAAAAAATATACACC
CTTTCAAATGGTGAATAATTACAAGTATATAGAAACAAAGTATGTTAATTTTGTACTAGAAAAACATTTAAACAAAAAAC
ATCTAAACATAATAGTAGGTATACCTAGTAGAGATATATCAAGAATAATTTTAACCTATTCTCAAAATAACATTAAAAAA
ACTTTAAATAAAGTTATCATTATAACACTAGTAATTGATAGCGTGGTAGCTTTAGGTGTAGGATATTTATTTAGTAGAAA
ACTTACAAAACCAATTTCAAGCGTACTATGGAGTATTGAGACTATGGCTAATGGAAATTATAGTTTATATCTTAAGGACA
GAGGTATATATGAAGAAGTTTTTAAAAATATAAATATGTTAGCTGATACTTTAAGAGTAAATGAAGTTGAGAGAAAAGAA
AATGAAGAGTTGAGAGAGGAATGGCTGGCAAATATAACACATGATATAAAGACACCTCTAGCATCTATACAAGGGTATGC
AGAGATAATTAATGACAAAGATTATGAGTTTGAAGAAGATGAAATACAAGAGTATACAGAAATTATATATAATAAGTCTA
AGTATATAAAAGATTTAGTTGATGATTTAAATTTATCTACTCGATTAAAAAATAATACTATAGTTCTGGACAAGAAAAAA
ATAAATTTAGTCAGTTTAGTCAGAAATATAATAATTGATATTTTAAATGATAATAGATATAAAAATAGGAATATTGAATT
TGAAAGTAATGAAGATTTAATTGAAGTATATATAGATTCAATCTTATTCAGAAGGGCTATAACCAATCTTATATTTAATT
CAATAGTTCATAATAGCGAAGGAACTTTGATAAGTGTAGAAATTGTAAAAAAAGATAATATAGAAATTATAATAAAAGAT
AATGGAATTGGAATAAGCAAAAGTGATTTGAAACATATTTTTAAAAAATATTATAGAGGTACTAATACAGGTGAGATGCA
TAAAGGTTCAGGTCTTGGTATGGCTATTTCTAAAGAAATAATAGAGATTCATAAAGGTAAAATTTATGTAAGTAGTGAAA
TTGGAATAGGAACAAAAATTATTATAGAGATAAAACAAAATTAG

Upstream 100 bases:

>100_bases
AAAAATTAGGGAAAAATTAGAGGATAATCCTTCAAAACCTGAATATATTCTGACAATAAAAGGTCTTGGATATAAATTAG
CAGTAAAGGAAGATTAGAAT

Downstream 100 bases:

>100_bases
GAGATATGATATGGATTTTTTTAAAAAAGGTATAAGTGGGTTTACTATTAAGATTTTAGCATTAATATTTATGACATTTG
ACCATATAGCAGCATTTATG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSGNNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNS
WIQVLNDLGEEVYGVNVPKDTPKKYTPFQMVNNYKYIETKYVNFVLEKHLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYEEVFKNINMLADTLRVNEVERKE
NEELREEWLANITHDIKTPLASIQGYAEIINDKDYEFEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKK
INLVSLVRNIIIDILNDNRYKNRNIEFESNEDLIEVYIDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKDNIEIIIKD
NGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYVSSEIGIGTKIIIEIKQN

Sequences:

>Translated_467_residues
MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSGNNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNS
WIQVLNDLGEEVYGVNVPKDTPKKYTPFQMVNNYKYIETKYVNFVLEKHLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYEEVFKNINMLADTLRVNEVERKE
NEELREEWLANITHDIKTPLASIQGYAEIINDKDYEFEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKK
INLVSLVRNIIIDILNDNRYKNRNIEFESNEDLIEVYIDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKDNIEIIIKD
NGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYVSSEIGIGTKIIIEIKQN
>Mature_467_residues
MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSGNNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNS
WIQVLNDLGEEVYGVNVPKDTPKKYTPFQMVNNYKYIETKYVNFVLEKHLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYEEVFKNINMLADTLRVNEVERKE
NEELREEWLANITHDIKTPLASIQGYAEIINDKDYEFEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKK
INLVSLVRNIIIDILNDNRYKNRNIEFESNEDLIEVYIDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKDNIEIIIKD
NGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYVSSEIGIGTKIIIEIKQN

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon. Probably activates yv

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=285, Percent_Identity=24.2105263157895, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786600, Length=286, Percent_Identity=26.2237762237762, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786783, Length=314, Percent_Identity=25.4777070063694, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788713, Length=268, Percent_Identity=24.6268656716418, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=25.531914893617, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI48994928, Length=223, Percent_Identity=23.7668161434978, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790436, Length=252, Percent_Identity=24.6031746031746, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790861, Length=326, Percent_Identity=24.2331288343558, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI145693157, Length=220, Percent_Identity=21.8181818181818, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788549, Length=249, Percent_Identity=23.6947791164659, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789149, Length=325, Percent_Identity=22.4615384615385, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789808, Length=287, Percent_Identity=22.2996515679443, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=23.2456140350877, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790346, Length=217, Percent_Identity=23.5023041474654, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53936; Mature: 53936

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSGNNPEEFARSFEKDLYE
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHH
KDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTPKKYTPFQMVNNYKYIETK
CCCCEEHHHHCHHHHHCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHCCCEEHHHH
YVNFVLEKHLNKKHLNIIVGIPSRDISRIILTYSQNNIKKTLNKVIIITLVIDSVVALGV
HHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
GYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYEEVFKNINMLADTLRVNEVERKE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
NEELREEWLANITHDIKTPLASIQGYAEIINDKDYEFEEDEIQEYTEIIYNKSKYIKDLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHH
DDLNLSTRLKNNTIVLDKKKINLVSLVRNIIIDILNDNRYKNRNIEFESNEDLIEVYIDS
HHCCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
ILFRRAITNLIFNSIVHNSEGTLISVEIVKKDNIEIIIKDNGIGISKSDLKHIFKKYYRG
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCC
TNTGEMHKGSGLGMAISKEIIEIHKGKIYVSSEIGIGTKIIIEIKQN
CCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCEEEEEEEECC
>Mature Secondary Structure
MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSGNNPEEFARSFEKDLYE
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHH
KDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTPKKYTPFQMVNNYKYIETK
CCCCEEHHHHCHHHHHCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHCCCEEHHHH
YVNFVLEKHLNKKHLNIIVGIPSRDISRIILTYSQNNIKKTLNKVIIITLVIDSVVALGV
HHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
GYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYEEVFKNINMLADTLRVNEVERKE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
NEELREEWLANITHDIKTPLASIQGYAEIINDKDYEFEEDEIQEYTEIIYNKSKYIKDLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHH
DDLNLSTRLKNNTIVLDKKKINLVSLVRNIIIDILNDNRYKNRNIEFESNEDLIEVYIDS
HHCCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
ILFRRAITNLIFNSIVHNSEGTLISVEIVKKDNIEIIIKDNGIGISKSDLKHIFKKYYRG
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCC
TNTGEMHKGSGLGMAISKEIIEIHKGKIYVSSEIGIGTKIIIEIKQN
CCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]