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The map label for this gene is pabB [H]

Identifier: 126699050

GI number: 126699050

Start: 1676723

End: 1678081

Strand: Direct

Name: pabB [H]

Synonym: CD1446

Alternate gene names: 126699050

Gene position: 1676723-1678081 (Clockwise)

Preceding gene: 126699049

Following gene: 126699051

Centisome position: 39.08

GC content: 29.73

Gene sequence:

>1359_bases
ATGTGTAATATGATAAGAGAGATAAATACTAAATTAAATTCTTTTGAGATATTTACTATTTTTAGAAATGAACATGACAG
TTTTATATTAGACAGTGCTATGGATAAAGAAAAATTGGGAAGATATTCTTTTATAAGTAGCCAACCATTTAAGGTATTAA
AGTATAAAGATACTGATGAAAATCCTTTAGAAGTTTTAAAAGAAGAACTACATAAGTATAGGGTTGTAAATGATACTAAT
CTTCCATTTGTAGGAGGTGCTGTGGGATATTTATCTTATGATTTAGGTAATTACATAGAAAATTTACCTAGAACTGCTGT
AGATGATATTGAGATGCCTGATATGTATTTTGGATTTTATAATCATGTAATAGTTATAGACCATCTTGTGCAAAAAACTT
ATATAGCTACTCCAAACATAGATATCGAATTAGAAGAAAAGATAATAGATAATATAGAACAAAGAATATTAAAAGAAGAG
AAAAAAGGTATAGATAGCATATGTTATGAAGAAAAAGAAGTAACACCTATAAGACTTAAATCTAATTTTACAAAGGAAGA
ATTTAAAAATGCAGTTCAAAGTGTTAGAGAGTACATAAGACAAGGAGATATATATCAAGCTAATTTAACACAAAGGTTCA
GTGGAGAAACAGAACTTACAAGCTTTGAATTGTATAGGGACTTAAGAAGATTTAGCCCGGCACCATTTGGGGCATTCTTA
AACTTTGAAGATGCACATATATTATCAAATTCTCCAGAAAGATTTATAAGATGTGTTAATAAGAGAATAGAAACTAGACC
AATAAAAGGTACTCGTCCAAGAGGGAAAGATAAAAAAGAAGATTTAAGACTTCAACAAGAACTTAGAAATAGTGAAAAAG
ATAGAGCTGAACTACTTATGATAGTAGATTTAGAAAGAAATGATATTGGCAGAATATCTAAAACTGGAAGTGTTAAAGTT
CCAGAGCTATTTGTAATTGAACCATATGCAAATGTAAATCACTTAGTTTCCACAGTTGTAGGTGAGTTAAAAGATGATAA
AGATGCTACTGATGTAATAAAAGCAACTTTTCCAGGGGGGTCTATAACAGGAGCACCTAAGATTAGAGCAATGGAAATTA
TAGACGAATTAGAGCCAACGCAAAGAAATGTATATACTGGTTCAATAGGTTATATAGGTTTTAATGGTGATATGGATTTT
AATATAGCAATTAGAACAATAATCAAAAATGACAAAAAAGTCTACTTTCAAGTTGGAGGAGGAATGACTTGGGATTCTGA
CCCAGATGAAGAATATCAAGAAACACTTGATAAAGCTAAATCCATAATGAAGGCTTTGAGGGGATATTATGAAGAATAA

Upstream 100 bases:

>100_bases
TATTTAATAGAAGGAGTACAGTTTCATCCAGAAGCTATTTTGTCAGAGTATGGTCATGAAATGCTTAAAAATTTTATAAC
AGAAGCTAGAGAAAGGGTAC

Downstream 100 bases:

>100_bases
TGTAGGTTTTGATAGTAGTTTAAGTAAATTTGGAATTGGTTTGTTTGAAACTATTAGAGTTAAAAATGGAATAGCAGTAG
ATTTAGATATCCATATAGAA

Product: para-aminobenzoate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MCNMIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISSQPFKVLKYKDTDENPLEVLKEELHKYRVVNDTN
LPFVGGAVGYLSYDLGNYIENLPRTAVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDNIEQRILKEE
KKGIDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTSFELYRDLRRFSPAPFGAFL
NFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKKEDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKV
PELFVIEPYANVNHLVSTVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFNGDMDF
NIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE

Sequences:

>Translated_452_residues
MCNMIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISSQPFKVLKYKDTDENPLEVLKEELHKYRVVNDTN
LPFVGGAVGYLSYDLGNYIENLPRTAVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDNIEQRILKEE
KKGIDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTSFELYRDLRRFSPAPFGAFL
NFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKKEDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKV
PELFVIEPYANVNHLVSTVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFNGDMDF
NIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE
>Mature_452_residues
MCNMIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISSQPFKVLKYKDTDENPLEVLKEELHKYRVVNDTN
LPFVGGAVGYLSYDLGNYIENLPRTAVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDNIEQRILKEE
KKGIDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTSFELYRDLRRFSPAPFGAFL
NFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKKEDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKV
PELFVIEPYANVNHLVSTVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFNGDMDF
NIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=435, Percent_Identity=42.2988505747126, Blast_Score=350, Evalue=2e-97,
Organism=Escherichia coli, GI1787518, Length=371, Percent_Identity=34.2318059299191, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI87082077, Length=200, Percent_Identity=26, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786809, Length=197, Percent_Identity=24.8730964467005, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=434, Percent_Identity=38.4792626728111, Blast_Score=274, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6324361, Length=502, Percent_Identity=27.6892430278884, Blast_Score=152, Evalue=9e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 52260; Mature: 52260

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCNMIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISSQPFKVLKYKDTDE
CCCHHHHHHCCCCCEEEEEEEECCCCCEEHHHHCCHHHCCCEEECCCCCCEEEEECCCCC
NPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRTAVDDIEMPDMYFGFY
CHHHHHHHHHHHEEEECCCCCCEECCHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHH
NHVIVIDHLVQKTYIATPNIDIELEEKIIDNIEQRILKEEKKGIDSICYEEKEVTPIRLK
HHHHHHHHHHHHHEECCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEC
SNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTSFELYRDLRRFSPAPFGAFL
CCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEE
NFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKKEDLRLQQELRNSEKDRAELLM
CCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
IVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVSTVVGELKDDKDATDVIKATFPGG
EEEECCCCCCCCCCCCCEECCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHEEEECCCC
SITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFNGDMDFNIAIRTIIKNDKKVYFQVGG
CCCCCCCHHHHHHHHHCCCCCCCEEECCEEEEEECCCCCEEEEEEEEECCCCEEEEEECC
GMTWDSDPDEEYQETLDKAKSIMKALRGYYEE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MCNMIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISSQPFKVLKYKDTDE
CCCHHHHHHCCCCCEEEEEEEECCCCCEEHHHHCCHHHCCCEEECCCCCCEEEEECCCCC
NPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRTAVDDIEMPDMYFGFY
CHHHHHHHHHHHEEEECCCCCCEECCHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHH
NHVIVIDHLVQKTYIATPNIDIELEEKIIDNIEQRILKEEKKGIDSICYEEKEVTPIRLK
HHHHHHHHHHHHHEECCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEC
SNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTSFELYRDLRRFSPAPFGAFL
CCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEE
NFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKKEDLRLQQELRNSEKDRAELLM
CCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
IVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVSTVVGELKDDKDATDVIKATFPGG
EEEECCCCCCCCCCCCCEECCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHEEEECCCC
SITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFNGDMDFNIAIRTIIKNDKKVYFQVGG
CCCCCCCHHHHHHHHHCCCCCCCEEECCEEEEEECCCCCEEEEEEEEECCCCEEEEEECC
GMTWDSDPDEEYQETLDKAKSIMKALRGYYEE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]