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The map label for this gene is malX [H]

Identifier: 126698935

GI number: 126698935

Start: 1550494

End: 1552071

Strand: Direct

Name: malX [H]

Synonym: CD1336

Alternate gene names: 126698935

Gene position: 1550494-1552071 (Clockwise)

Preceding gene: 126698934

Following gene: 126698936

Centisome position: 36.14

GC content: 30.1

Gene sequence:

>1578_bases
ATGAAACAAAAAATGAAAGAATTCTTTTTACAGTTAGGAAAATCATTTTTATTGCCAATAGCATTAATATCTGCAGCAGG
TATATTTTTAGGAATAAGTTCAGCATTTTCAAATCCTAATATAGTTAGTGATATGCCTTTTTTAGCAAATAATTTTATTC
AAGGAATATTGGGTTTTACAAAAGCTATAACAGGAGTACTTTTTGGAAACTTAGCAATATTCTTTGCTATATCAATATCT
GTTGGTCTTGCTAAAGAAGAAAAAGCAGTTTCTGCATTTTCTGGTTTTGTTGGTTATTTAGTATTACACACTAGTATAAA
TTATATGTTAGGGTGTAGGGGGATTCTTGCTGAACCTGACATGATGAGAGAAATGGGTCAAGCTGTAACTTTAGGCATAC
AAACATTAGAATTAGGAGTATTTGGTGGAATTGTAGTTGGTATAATAACAGCATCATTACATAATAAATACTATAATATA
AAACTGCCAGATTATTTAGGATTCTTTGGTGGAACTAGGTTTGTTCCAATAATAACAACAGTAGTATTCTCTATTTTGGG
GATAATAATACCATATATATGGCCATATGTAAATACAATTATTCAGAGTGTAGGTATTGGTATAGCTAGTTTAGGATATT
TAGGAACATTTGTATTTGGGTTTCTTGAAAGACTTTTAATACCATTTGGATTACATCATATATTAAATGCTATGTTTAGA
TTTACTGAAGTAGGAGGTTCTTTAGTTGTGGGAGGGCAAGAAGTATTTGGAGCATTAAACATATTCTTAGCTCAACTAAG
TGACCCTGAAACAATCAGTTTTTCAACAGAAGCAACTAGATTTTTAGCTCAAGGGAAAATACCTATAATGGTATTTGGTC
TTCCTGCTGCTGCATATGCCATGTATAAAACTGCAAAGCCTGAAAATAGGTCGAAGGTTAAAGGTATATTACTAGCTGGT
GCTTTAGCAACATTTGTAACAGGAATTACGGAACCATTGGAATTTTCATTCTTATTTGTATCACCAATATTATTTGTTAT
ACATGCATTTTTATCAGGTATATCATTTATGATGATGCATATATTTGGAGTAGCAATAGGAAATACTCAAGGTGGCATAA
TAGATTTAGTAGTATTTGGAGTTATGCAACCAAATACAAAGTGGATTTATTCTATAATACTTGGTTTGGTGTATGCAATA
GTTTATTATAATGTATTTAAGATTTTGATACTTAGATTTAACTTACAAACTCCAGGACGAGAAGAAATAACAGATATAAA
TTTTGATTTAGAACCTTTATCAAATAAAGTAGAAATAGCTCAAAGTGGAGAAACTACTAAGAGAGCATTATCTATAATTA
AATATTTAGGTGGTAAGGACAATATAGAAGATATAACAAACTGTATAACTCGCTTAAGAGTAGTAGTTAAAGATATGAGT
AAAGTAGATGAAAATGCTTTTAAAAAATATACAGGTGCAATGGGAGTTATAAAAGTATCTGATAAAGATATCCAAATAAT
TTATGGGCCATCTGTATCTCAAGTAAGAGACGAAGTTTCTTTTGCAATGTCTATTTAA

Upstream 100 bases:

>100_bases
AAAATATTTTAAAACAAATTATAAAGTTTCAAAAACAAAATAAAAATATATAATTATGACATAGAAAACGTTTTAAAAAT
TTAAAAATGGAGGGATAGAA

Downstream 100 bases:

>100_bases
AGTAAATATTAAAAGGCAATACTAATTTATAATTTGTATTGTCTTTTTTGTAGTATAATAAACATAAGATAAATGCTGTA
TAGTGTATATTTATATAATA

Product: PTS system maltose and glucose-specific transporter subunit IIBC

Products: NA

Alternate protein names: Maltose and glucose permease IIC component; PTS system maltose- and glucose-specific EIIC component; Maltose- and glucose-specific phosphotransferase enzyme IIB component; PTS system maltose- and glucose-specific EIIB component [H]

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MKQKMKEFFLQLGKSFLLPIALISAAGIFLGISSAFSNPNIVSDMPFLANNFIQGILGFTKAITGVLFGNLAIFFAISIS
VGLAKEEKAVSAFSGFVGYLVLHTSINYMLGCRGILAEPDMMREMGQAVTLGIQTLELGVFGGIVVGIITASLHNKYYNI
KLPDYLGFFGGTRFVPIITTVVFSILGIIIPYIWPYVNTIIQSVGIGIASLGYLGTFVFGFLERLLIPFGLHHILNAMFR
FTEVGGSLVVGGQEVFGALNIFLAQLSDPETISFSTEATRFLAQGKIPIMVFGLPAAAYAMYKTAKPENRSKVKGILLAG
ALATFVTGITEPLEFSFLFVSPILFVIHAFLSGISFMMMHIFGVAIGNTQGGIIDLVVFGVMQPNTKWIYSIILGLVYAI
VYYNVFKILILRFNLQTPGREEITDINFDLEPLSNKVEIAQSGETTKRALSIIKYLGGKDNIEDITNCITRLRVVVKDMS
KVDENAFKKYTGAMGVIKVSDKDIQIIYGPSVSQVRDEVSFAMSI

Sequences:

>Translated_525_residues
MKQKMKEFFLQLGKSFLLPIALISAAGIFLGISSAFSNPNIVSDMPFLANNFIQGILGFTKAITGVLFGNLAIFFAISIS
VGLAKEEKAVSAFSGFVGYLVLHTSINYMLGCRGILAEPDMMREMGQAVTLGIQTLELGVFGGIVVGIITASLHNKYYNI
KLPDYLGFFGGTRFVPIITTVVFSILGIIIPYIWPYVNTIIQSVGIGIASLGYLGTFVFGFLERLLIPFGLHHILNAMFR
FTEVGGSLVVGGQEVFGALNIFLAQLSDPETISFSTEATRFLAQGKIPIMVFGLPAAAYAMYKTAKPENRSKVKGILLAG
ALATFVTGITEPLEFSFLFVSPILFVIHAFLSGISFMMMHIFGVAIGNTQGGIIDLVVFGVMQPNTKWIYSIILGLVYAI
VYYNVFKILILRFNLQTPGREEITDINFDLEPLSNKVEIAQSGETTKRALSIIKYLGGKDNIEDITNCITRLRVVVKDMS
KVDENAFKKYTGAMGVIKVSDKDIQIIYGPSVSQVRDEVSFAMSI
>Mature_525_residues
MKQKMKEFFLQLGKSFLLPIALISAAGIFLGISSAFSNPNIVSDMPFLANNFIQGILGFTKAITGVLFGNLAIFFAISIS
VGLAKEEKAVSAFSGFVGYLVLHTSINYMLGCRGILAEPDMMREMGQAVTLGIQTLELGVFGGIVVGIITASLHNKYYNI
KLPDYLGFFGGTRFVPIITTVVFSILGIIIPYIWPYVNTIIQSVGIGIASLGYLGTFVFGFLERLLIPFGLHHILNAMFR
FTEVGGSLVVGGQEVFGALNIFLAQLSDPETISFSTEATRFLAQGKIPIMVFGLPAAAYAMYKTAKPENRSKVKGILLAG
ALATFVTGITEPLEFSFLFVSPILFVIHAFLSGISFMMMHIFGVAIGNTQGGIIDLVVFGVMQPNTKWIYSIILGLVYAI
VYYNVFKILILRFNLQTPGREEITDINFDLEPLSNKVEIAQSGETTKRALSIIKYLGGKDNIEDITNCITRLRVVVKDMS
KVDENAFKKYTGAMGVIKVSDKDIQIIYGPSVSQVRDEVSFAMSI

Specific function: MalX encodes a phosphotransferase system enzyme II that can recognize glucose and maltose as substrates even though these sugars may not represent the natural substrates of the system [H]

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=522, Percent_Identity=46.551724137931, Blast_Score=476, Evalue=1e-135,
Organism=Escherichia coli, GI1787343, Length=514, Percent_Identity=36.7704280155642, Blast_Score=298, Evalue=6e-82,
Organism=Escherichia coli, GI1786894, Length=512, Percent_Identity=34.765625, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI48994906, Length=71, Percent_Identity=46.4788732394366, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011301 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 57339; Mature: 57339

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQKMKEFFLQLGKSFLLPIALISAAGIFLGISSAFSNPNIVSDMPFLANNFIQGILGFT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
KAITGVLFGNLAIFFAISISVGLAKEEKAVSAFSGFVGYLVLHTSINYMLGCRGILAEPD
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
MMREMGQAVTLGIQTLELGVFGGIVVGIITASLHNKYYNIKLPDYLGFFGGTRFVPIITT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCHHHHHHHH
VVFSILGIIIPYIWPYVNTIIQSVGIGIASLGYLGTFVFGFLERLLIPFGLHHILNAMFR
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTEVGGSLVVGGQEVFGALNIFLAQLSDPETISFSTEATRFLAQGKIPIMVFGLPAAAYA
HHHCCCCEEECHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCEEEEECCHHHHH
MYKTAKPENRSKVKGILLAGALATFVTGITEPLEFSFLFVSPILFVIHAFLSGISFMMMH
HHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFGVAIGNTQGGIIDLVVFGVMQPNTKWIYSIILGLVYAIVYYNVFKILILRFNLQTPGR
HHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EEITDINFDLEPLSNKVEIAQSGETTKRALSIIKYLGGKDNIEDITNCITRLRVVVKDMS
CCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
KVDENAFKKYTGAMGVIKVSDKDIQIIYGPSVSQVRDEVSFAMSI
HHHHHHHHHHHCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856179; 9097039; 9278503; 2670898 [H]