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The map label for this gene is ccpA [H]

Identifier: 126698651

GI number: 126698651

Start: 1257133

End: 1258149

Strand: Direct

Name: ccpA [H]

Synonym: CD1064

Alternate gene names: 126698651

Gene position: 1257133-1258149 (Clockwise)

Preceding gene: 126698650

Following gene: 126698653

Centisome position: 29.3

GC content: 30.97

Gene sequence:

>1017_bases
ATGAAAGGCAATATAACGATAAAAGATGTTGCTAAACAAGCAGGAGTGTCAATATCTACTGTATCTAGAGTTATAAATGA
TTCAAAACCTGTAACTGATGAAGTCAAACAAAAAGTTTTAGAGGTTATAAAAGAGACTGGATATATACCAAATCCACTTG
CTAGAAGCTTAGTAACAAAGAAGAGTCAATTAATAGGGGTAATAGTTCCAGAAGTTTCAGATTCTTTTGTTAATGAGGTG
TTAAATGGGATAGAAGAGGTTGCTAAAATGTATGACTATGATATTCTTTTAGCGAATACATACTCTGATAAGGAACAAGA
ACTTAAGAGTATAAATCTATTGAGAGCAAAACAAGTGGAAGGTATAGTTATGATTTCATGGATAGTTGAACAAGAACATA
TCAACTATATACAAAATTGTGGAATACCAGCGACATATATAAGTAAAACTGCTAGAAATTATGATATATATACAGTAAGT
ACTAGCAACGAAGAAGCTACTTTTGATATGACAGAGCATCTTATAAAGAAAGGTCATGAAAAGATAGCTTTTATAATGAC
GAGTAAAGATGATACTGTTTTAGAAATGGAAAGACTTGCTGGTTATGAGAAAGCACTTTCAAATAACAATATAGAATTAG
ACAAGAGTTTGATTAAGTATGGTGGAACTGATTATGAGAGTGGATACAATAGTATGAAAGAACTATTAGATGATGGAATA
ATACCTCATGCGGCTTTTGTAACAGGTGATGAGGCTGCCATAGGTGCTATAAATGCTATATGTGATGCTGGATATAAGGT
TCCAGAAGACATATCTGTTGCAGGATTTAATGATGTTAAGATAGCTAGAATGTATAGACCTAAACTTACTACAGTATATC
AACCTCTATACGATATGGGAGCAGTAGCAATAAGAATGGTTATAAAATTAATAAATAAGGAATTAATTGAAAATAAGAAA
ATAGAATTACCTTATAGAATTGTTGATAGAGAAAGTGTTACAGAAAGAAAAAAATAA

Upstream 100 bases:

>100_bases
TTTATGGTAAAATAAAAACTTATATAAATGTAGTTAAAATAGGAACCTTCAAAAATTTGGTTCAGTTTTAGATAAATTTA
GTAAAATAAGGAGGATGAAG

Downstream 100 bases:

>100_bases
AACTATTAAAATCAATCAGGTAGTGCCTAAGGCACTACCTGATTTTTTATGTCAATAATATCAAATTTAATAATAGATTA
ACTAAAAATAATTATCTAAT

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIKETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEV
LNGIEEVAKMYDYDILLANTYSDKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLIKYGGTDYESGYNSMKELLDDGI
IPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGFNDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKK
IELPYRIVDRESVTERKK

Sequences:

>Translated_338_residues
MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIKETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEV
LNGIEEVAKMYDYDILLANTYSDKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLIKYGGTDYESGYNSMKELLDDGI
IPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGFNDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKK
IELPYRIVDRESVTERKK
>Mature_338_residues
MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIKETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEV
LNGIEEVAKMYDYDILLANTYSDKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLIKYGGTDYESGYNSMKELLDDGI
IPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGFNDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKK
IELPYRIVDRESVTERKK

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=310, Percent_Identity=32.258064516129, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1790194, Length=329, Percent_Identity=30.0911854103343, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1787948, Length=332, Percent_Identity=31.6265060240964, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1788474, Length=338, Percent_Identity=31.6568047337278, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1789202, Length=294, Percent_Identity=30.6122448979592, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789068, Length=297, Percent_Identity=32.6599326599327, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1786540, Length=330, Percent_Identity=29.3939393939394, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1787580, Length=313, Percent_Identity=28.4345047923323, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1790715, Length=323, Percent_Identity=27.5541795665635, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI48994940, Length=324, Percent_Identity=27.1604938271605, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787906, Length=335, Percent_Identity=25.6716417910448, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786268, Length=314, Percent_Identity=21.9745222929936, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790689, Length=295, Percent_Identity=19.6610169491525, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37874; Mature: 37874

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIKETGYIPNPLARSLVTK
CCCCEEHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
KSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYSDKEQELKSINLLRAKQVE
HHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCC
GIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVSTSNEEATFDMTEHLIKKGHE
CEEEEHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCC
KIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLIKYGGTDYESGYNSMKELLDDGI
EEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
IPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGFNDVKIARMYRPKLTTVYQPLYDMG
CCCEEEECCCCHHHHHHHHHHHCCCCCCCCCEECCCCCEEEHHHHCCHHHHHHHHHHHHH
AVAIRMVIKLINKELIENKKIELPYRIVDRESVTERKK
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHCCC
>Mature Secondary Structure
MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIKETGYIPNPLARSLVTK
CCCCEEHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
KSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYSDKEQELKSINLLRAKQVE
HHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCC
GIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVSTSNEEATFDMTEHLIKKGHE
CEEEEHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCC
KIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLIKYGGTDYESGYNSMKELLDDGI
EEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
IPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGFNDVKIARMYRPKLTTVYQPLYDMG
CCCEEEECCCCHHHHHHHHHHHCCCCCCCCCEECCCCCEEEHHHHCCHHHHHHHHHHHHH
AVAIRMVIKLINKELIENKKIELPYRIVDRESVTERKK
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]