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The map label for this gene is ywbA [H]

Identifier: 126698439

GI number: 126698439

Start: 1038389

End: 1039693

Strand: Direct

Name: ywbA [H]

Synonym: CD0862

Alternate gene names: 126698439

Gene position: 1038389-1039693 (Clockwise)

Preceding gene: 126698438

Following gene: 126698440

Centisome position: 24.2

GC content: 30.96

Gene sequence:

>1305_bases
TTGGGGGGAATAAAAATGGAAGCACTTCAAAATAATTTAAGAAGATTTCTTCTTCCAATAGCACAAAAGATTGAAAAACA
AAGGCATCTTCAAGCTATAAAAGAAGGTATGATAAGCATTACCCCAATAATAATTGTTGGTTCTTTAAGTATGTTATTTA
TGGCATTAAACAATATGTTACCTGAAGGAAGTGCAAAAACATTATTATCTGAAAATATGGATACATTACTTATCCCTAAT
AAATTTACTATGAGTTTATTATCTATATATTCAGCATTTTTTATAGCTCAGGCACTAGCTAAAAAATATAATCTTAATCA
TGTAGAAATAGGTATGACAGCAGTTGTTGCACAACTTGTTGTATGTGGGCAAGTAGTAGATGGTGTATTAGATACAAGTT
ATTTAGATGCACAAGGTTTATTTGTAAGTATATTAGTAGCACTTTTAGTAGTTGATATTACTAAGTTTATGAATGATAAA
AATCTCGTAATTAGATTTCCAAAAGAAGTACCTAGTGTAGTAAATAAAAGTTTTAGAAACTTAACTCCAATGATAGTATG
TATAATGTTATTTACAGCAATAGCAGCAATAACTAAAAATGTCTCAGGTCAACCACTACCAGCTATTATAATGAATTTCT
TAGCACCAGCTATAAGCAGTGTAGATAATGTTTTTGCAGTAACTATAATACTATTTATAACTCAATTATTATGGTTCTTT
GGGCTTCATGGAGCAGCAATAACTTCAAGTATATGGATGCCAATAGCAGCTACATATATGGCAGAAAATGCAACACTGAT
AGCAGCAGGAGGAGACCCAAAATATGTGTTTACAATAGGTTTTTACTATGGTTTCTTGCAAGTAACTGGTTCAGGGATAA
CTTTGGGATTAGTGTACCTTATGTCAAGAAGTAAGTGTAAAAGTTTTAATAGTATGGGAAAAGTTGTGATTTTACCATCA
CTATTTGGAATAAATGAGCCAGTAATATTTGGAACACCAATAGTTATGAACCCATATATGTTTGTACCATTTGTATTTGG
ACCTGTATTGGTTGGAGCACTTAATTTTATGGCATTAAAAGTAGGATTAGTAGGATTACCTATTGCAGAACCACCAGGTT
TTTTACCTCCAGGGGTTGCAGCATTTTTGATGACATTAGATTGGAAGGCAATCGTATTAGTATTTGCAAGTATAATACTT
ATGACCTTGATATATTATCCATTCTTTAAGATAATGGAGAAGGAAGAATTAAATAAAAATGCAGAATTAGCTACAACATT
AGATGATGATAGCTTTGATTTTTAA

Upstream 100 bases:

>100_bases
TTACAAAATAGCAGTTGGTTTAATAGATACTAAGCATTATGGTCGTATGGATGCTCCTTCTGTTATGAAGTCGGCAATCG
AATTATATAAAAATAGATAA

Downstream 100 bases:

>100_bases
CAAGTCATTAGAAGGAGAAGGATATGGTACCTGAAATGGAAGAAAAAGTATTTAGTATAATATCAGAAGCAGGAGATGCT
AAAAGTGATGTAATGATGTC

Product: PTS system transporter subunit IIC

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: Putative PTS system EIIC component [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MGGIKMEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSLSMLFMALNNMLPEGSAKTLLSENMDTLLIPN
KFTMSLLSIYSAFFIAQALAKKYNLNHVEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDK
NLVIRFPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDNVFAVTIILFITQLLWFF
GLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGFYYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPS
LFGINEPVIFGTPIVMNPYMFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFASIIL
MTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF

Sequences:

>Translated_434_residues
MGGIKMEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSLSMLFMALNNMLPEGSAKTLLSENMDTLLIPN
KFTMSLLSIYSAFFIAQALAKKYNLNHVEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDK
NLVIRFPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDNVFAVTIILFITQLLWFF
GLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGFYYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPS
LFGINEPVIFGTPIVMNPYMFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFASIIL
MTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF
>Mature_433_residues
GGIKMEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSLSMLFMALNNMLPEGSAKTLLSENMDTLLIPNK
FTMSLLSIYSAFFIAQALAKKYNLNHVEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKN
LVIRFPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDNVFAVTIILFITQLLWFFG
LHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGFYYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSL
FGINEPVIFGTPIVMNPYMFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFASIILM
TLIYYPFFKIMEKEELNKNAELATTLDDDSFDF

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=433, Percent_Identity=30.2540415704388, Blast_Score=163, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 47492; Mature: 47360

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGIKMEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSLSMLFMALNNML
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHC
PEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNHVEIGMTAVVAQLV
CCCCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
VCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIRFPKEVPSVVNKSFRN
HHHHHHHHHHCCCHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHH
LTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDNVFAVTIILFITQLLWFF
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGFYYGFLQVTGSGITLGLVYL
CCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEHHHHHHHHHHCCCCHHHHHHHH
MSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPYMFVPFVFGPVLVGALNFMALK
HHHHHHHHHHHCCCEEEEEHHHCCCCCEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHH
VGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFASIILMTLIYYPFFKIMEKEELNKN
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AELATTLDDDSFDF
CCEEEEECCCCCCC
>Mature Secondary Structure 
GGIKMEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSLSMLFMALNNML
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHC
PEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNHVEIGMTAVVAQLV
CCCCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
VCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIRFPKEVPSVVNKSFRN
HHHHHHHHHHCCCHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHH
LTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDNVFAVTIILFITQLLWFF
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGFYYGFLQVTGSGITLGLVYL
CCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEHHHHHHHHHHCCCCHHHHHHHH
MSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPYMFVPFVFGPVLVGALNFMALK
HHHHHHHHHHHCCCEEEEEHHHCCCCCEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHH
VGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFASIILMTLIYYPFFKIMEKEELNKN
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AELATTLDDDSFDF
CCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]