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The map label for this gene is bglC [H]

Identifier: 126698398

GI number: 126698398

Start: 992746

End: 994152

Strand: Direct

Name: bglC [H]

Synonym: CD0818

Alternate gene names: 126698398

Gene position: 992746-994152 (Clockwise)

Preceding gene: 126698397

Following gene: 126698399

Centisome position: 23.14

GC content: 31.41

Gene sequence:

>1407_bases
ATGAATACAGGATTTCCAAAAGACTTTTTATGGGGAGCATCATCTTCTGCATTTCAAGTGGAAGGAGCTTGGGATAAAGA
CAATAAAGGAAAAACCGTAGCCGACTATAATTCTTTTAAAAAATCTCATTTACAGGCAGATACTAAAGTCGCATCAGACT
TTTACCATAATTATGAAGAAGATATTGAATTAATGAAAGAATTAGGGATGAAAACATATCGTTTTTCAATTTCATGGGCA
AGAATAATACCAGATGGTGAAGGAGAGATAAACCAGAAAGGTTTAGACTTTTATAATAAGATAATAGACAAACTAATAGA
GTGTGATATTGAGCCATTCGTAACTTTATACCATTTTGACCTTCCATTTAAATTAGTAGAGAAATATAATGGTTGGGAAA
GTAGAGAAACTGTCTATGCTTTTGAAAGATTTGCTAAAATATGCTTTAAGCATTTTGGAGATAGGGTAAAGTATTGGCAA
CCTCATAATGAACAGAATTTAATTGTTAGAGTGGAGGAGAGAATTAATATATATGATGAAACAGATTCATGGAAGATAGA
TAAAATACGTGCTCAGATGGATTATAATCTTTGCTTAGCACATGCATTAGCAGTCAATGCATGTCATGAGATGATAAAAG
AAAGTAAAATTGGAGCAGCAGTATCATCATCTGTAACATATCCTCTTACTTCTAAGCCAGAAGATGTATATGCAGCTAGA
ATGAATGATAATTTTAAAGTGTACTATATGCTTGATATGCATCATTATGGAGAATATCCAGGGTATTATATGAAGTATCT
TGAAAAAAGAAATATAGTTCCTCACATGGAAGATGGGGATAAAGAGATACTTAAAAAAGCTAAAATGGATTTTATAGCTG
TAAATTATTATAGGACAAATTGTGCAGAAGCTTTACCTGAAGATTCACAACATCCATTTGGATTAAGAGAAGGAACTGTT
GATTTTAGTATGTATGGACTATTTAAAATGTCAATGAATCCTAACTTAGAGGCTTCTGAGTATGGAGCAGCAATAGACCC
ATCAGGTCTTAGAGTTGCCTTAAATGAATATTGGCAAAGATATCACTTACCTGTTATAATAACAGAAAATGGTCTAGGAG
CTAAAGATATATTAGAAGATGGAAAAATTCATGATGACTATCGTATAGACTATTTAAGAAGTCATATAAATGCATGTAAA
CTAGCTATTGAAGATGGTGTAGAGATGATTGGATATTGTCCATGGTCATTTACAGACCTTTTAAGTTCTTCTCAAGGTTT
TAATAAGCGTTATGGACTTGTTTATATAAATAGAACTGACCATGAAGTTTTAGATTTAAAAAGAATCAAGAAAGATAGTT
TTTACTGGTATAAAGAAGTTATAGAGAACAATGGAATAGTAAAATAA

Upstream 100 bases:

>100_bases
ATCTATCTCAATGAAATAACAAAGAAAAGAGTTAATATAGAGTGAACTTATTGCAATGAATCAACAAAGAAAATAATCAA
TATAAAAAGGAGAAATATTT

Downstream 100 bases:

>100_bases
ACATAAATATATATTGAGGGTTTTAGTATGTACATTACAAAGGTATTAAATAATTCGTTGCTACTTGCAAAGGATGATAA
TGATGAAGAAATAATATTGA

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHLQADTKVASDFYHNYEEDIELMKELGMKTYRFSISWA
RIIPDGEGEINQKGLDFYNKIIDKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
PHNEQNLIVRVEERINIYDETDSWKIDKIRAQMDYNLCLAHALAVNACHEMIKESKIGAAVSSSVTYPLTSKPEDVYAAR
MNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHMEDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTV
DFSMYGLFKMSMNPNLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYLRSHINACK
LAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIKKDSFYWYKEVIENNGIVK

Sequences:

>Translated_468_residues
MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHLQADTKVASDFYHNYEEDIELMKELGMKTYRFSISWA
RIIPDGEGEINQKGLDFYNKIIDKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
PHNEQNLIVRVEERINIYDETDSWKIDKIRAQMDYNLCLAHALAVNACHEMIKESKIGAAVSSSVTYPLTSKPEDVYAAR
MNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHMEDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTV
DFSMYGLFKMSMNPNLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYLRSHINACK
LAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIKKDSFYWYKEVIENNGIVK
>Mature_468_residues
MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHLQADTKVASDFYHNYEEDIELMKELGMKTYRFSISWA
RIIPDGEGEINQKGLDFYNKIIDKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
PHNEQNLIVRVEERINIYDETDSWKIDKIRAQMDYNLCLAHALAVNACHEMIKESKIGAAVSSSVTYPLTSKPEDVYAAR
MNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHMEDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTV
DFSMYGLFKMSMNPNLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYLRSHINACK
LAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIKKDSFYWYKEVIENNGIVK

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=482, Percent_Identity=31.1203319502075, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI110681710, Length=484, Percent_Identity=30.1652892561983, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI13273313, Length=485, Percent_Identity=31.340206185567, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI28376633, Length=485, Percent_Identity=27.4226804123711, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI24497614, Length=493, Percent_Identity=28.3975659229209, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI190360571, Length=97, Percent_Identity=42.2680412371134, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI2367270, Length=478, Percent_Identity=38.9121338912134, Blast_Score=339, Evalue=3e-94,
Organism=Escherichia coli, GI1789070, Length=482, Percent_Identity=37.551867219917, Blast_Score=325, Evalue=3e-90,
Organism=Escherichia coli, GI2367174, Length=484, Percent_Identity=37.8099173553719, Blast_Score=322, Evalue=3e-89,
Organism=Caenorhabditis elegans, GI17552856, Length=494, Percent_Identity=32.7935222672065, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17539390, Length=482, Percent_Identity=29.045643153527, Blast_Score=191, Evalue=5e-49,
Organism=Drosophila melanogaster, GI21356577, Length=473, Percent_Identity=27.4841437632135, Blast_Score=185, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54656; Mature: 54656

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHLQADTKVASDFYHNYEE
CCCCCCCHHHCCCCCCCEEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCHHH
DIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKIIDKLIECDIEPFVTLYHFD
HHHHHHHCCCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEC
LPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQPHNEQNLIVRVEERINIYDE
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEEEEC
TDSWKIDKIRAQMDYNLCLAHALAVNACHEMIKESKIGAAVSSSVTYPLTSKPEDVYAAR
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEECCCCCCCCCEEEEE
MNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHMEDGDKEILKKAKMDFIAVNYYRTN
ECCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEEEHHH
CAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNPNLEASEYGAAIDPSGLRVALNEYWQR
HHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHCCCEECCCCCEEHHHHHHHH
YHLPVIITENGLGAKDILEDGKIHDDYRIDYLRSHINACKLAIEDGVEMIGYCPWSFTDL
HCCCEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH
LSSSQGFNKRYGLVYINRTDHEVLDLKRIKKDSFYWYKEVIENNGIVK
HCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHLQADTKVASDFYHNYEE
CCCCCCCHHHCCCCCCCEEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCHHH
DIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKIIDKLIECDIEPFVTLYHFD
HHHHHHHCCCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEC
LPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQPHNEQNLIVRVEERINIYDE
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEEEEC
TDSWKIDKIRAQMDYNLCLAHALAVNACHEMIKESKIGAAVSSSVTYPLTSKPEDVYAAR
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEECCCCCCCCCEEEEE
MNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHMEDGDKEILKKAKMDFIAVNYYRTN
ECCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEEEHHH
CAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNPNLEASEYGAAIDPSGLRVALNEYWQR
HHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHCCCEECCCCCEEHHHHHHHH
YHLPVIITENGLGAKDILEDGKIHDDYRIDYLRSHINACKLAIEDGVEMIGYCPWSFTDL
HCCCEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH
LSSSQGFNKRYGLVYINRTDHEVLDLKRIKKDSFYWYKEVIENNGIVK
HCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]