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The map label for this gene is pheS [H]

Identifier: 126698278

GI number: 126698278

Start: 849702

End: 850730

Strand: Direct

Name: pheS [H]

Synonym: CD0699

Alternate gene names: 126698278

Gene position: 849702-850730 (Clockwise)

Preceding gene: 126698277

Following gene: 126698279

Centisome position: 19.81

GC content: 34.5

Gene sequence:

>1029_bases
GTGATATGTGTGCAAGAAAAATTACTTGCTTTACGTGAAGCAGCTTTGGCTGAAATAAAAGAAGCACAAAGCATAGAAAG
TGTAGAAAGTTTAAGAGTTAAGTACTTAGGAAAAAAAGGTGAGATAACTGCCATACTTAAAGAAATGGGTAAATTATCTG
CTGAAGAAAGACCAGTAGTTGGTAAGGTTGCCAATGAGGTAAGAGAAAACATTGAACTTAGCATAAATTCTAAAAAAGAA
GAAATAAATGCTATTGAAAAAGAAAGAAAATTAAAAGAGGAAGTGATAGATGTTACTCAACCAGGAAAAGTTTTAAAGGT
TGGGAAGAAGCATCCAATAACTCAAATTATAGATGAAGTAACAGATATATTTATCGGAATGGGATTCTCTATAGCAGAAG
GGCCAGAAGTTGAGACTGTTGAAAACAACTTTGACGCATTAAACGCTCCTAAAGACCATCCATCAAGAGATATGAGCGAT
ACATTCTATATCAATGATGGGGTATTACTTAGAACTCAAACATCTCCAGTTCAAGTAAGAACTATGAGAAGTCAAGAGTT
ACCAATAAAAGTAATTGCACCAGGTAGATGTTTTAGGTCAGACTCGCCAGATGCTACACACTCACCAATGTTCCATCAGA
TAGAAGGGCTTGTTGTTGGAAAAGATGTTACTATGGCAGAATTTAAAGGAACTATGGATATCTTCGTTGAAAAATTGTTT
GGTTCTGATATCAAAACTAAGTTTAGACCTCACAACTTCCCATTTACAGAACCAAGTGCAGAGGTTGATGTTACTTGTTT
CAAATGTGGTGGTAAAGGTTGCCCAATGTGTAAATATGAAGGTTGGATAGAAATATTAGGTTCAGGTATGGTTCATCCAA
ATGTGCTTAGAAATTGTGGAATAGACCCAGAAGTTTACAGTGGATTTGCATTTGGAGTTGGGGTTGAAAGACTTGCAATG
CTTAAATACGAAATAGATGATATTAGATTATTATTCGAAAATGATATGAGATTCTTAAATCAATTTTAA

Upstream 100 bases:

>100_bases
ATTTTTAAATTGTTAAACTACTAGGGTGGTACCGCGAAACTATAGCCTTTCGTCCCTAGACAGGGATTGAGGGGCTTTTT
TTATACAAAAAAACGAAAGG

Downstream 100 bases:

>100_bases
TTAGGAGGGTATGTAGATGTTAGTATCTTTAAAATGGCTTAGAGACTATGTTGATATAGACATAGATGTAAAAGAGTTCG
CTGATAAAATGACAATGACA

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MICVQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILKEMGKLSAEERPVVGKVANEVRENIELSINSKKE
EINAIEKERKLKEEVIDVTQPGKVLKVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSD
TFYINDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGKDVTMAEFKGTMDIFVEKLF
GSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKYEGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAM
LKYEIDDIRLLFENDMRFLNQF

Sequences:

>Translated_342_residues
MICVQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILKEMGKLSAEERPVVGKVANEVRENIELSINSKKE
EINAIEKERKLKEEVIDVTQPGKVLKVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSD
TFYINDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGKDVTMAEFKGTMDIFVEKLF
GSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKYEGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAM
LKYEIDDIRLLFENDMRFLNQF
>Mature_342_residues
MICVQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILKEMGKLSAEERPVVGKVANEVRENIELSINSKKE
EINAIEKERKLKEEVIDVTQPGKVLKVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSD
TFYINDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGKDVTMAEFKGTMDIFVEKLF
GSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKYEGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAM
LKYEIDDIRLLFENDMRFLNQF

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5729820, Length=290, Percent_Identity=30.6896551724138, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4758340, Length=271, Percent_Identity=30.9963099630996, Blast_Score=119, Evalue=5e-27,
Organism=Escherichia coli, GI1788007, Length=335, Percent_Identity=48.955223880597, Blast_Score=350, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI32566635, Length=276, Percent_Identity=33.695652173913, Blast_Score=130, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17508957, Length=278, Percent_Identity=31.294964028777, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI32563657, Length=278, Percent_Identity=31.294964028777, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6321087, Length=367, Percent_Identity=25.8855585831063, Blast_Score=125, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6325304, Length=288, Percent_Identity=28.4722222222222, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17137424, Length=289, Percent_Identity=31.4878892733564, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI18858079, Length=272, Percent_Identity=31.9852941176471, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 38320; Mature: 38320

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICVQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILKEMGKLSAEERPVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCH
GKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVLKVGKKHPITQIIDEV
HHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHH
TDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFYINDGVLLRTQTSPVQVR
HHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCEEEE
TMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGKDVTMAEFKGTMDIFVEKLF
EECCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHCCEEECCCCCHHHHCCHHHHHHHHHH
GSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKYEGWIEILGSGMVHPNVLRNCG
CCCHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHCCCCCCHHHHHHCC
IDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMRFLNQF
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MICVQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILKEMGKLSAEERPVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCH
GKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVLKVGKKHPITQIIDEV
HHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHH
TDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFYINDGVLLRTQTSPVQVR
HHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCEEEE
TMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGKDVTMAEFKGTMDIFVEKLF
EECCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHCCEEECCCCCHHHHCCHHHHHHHHHH
GSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKYEGWIEILGSGMVHPNVLRNCG
CCCHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHCCCCCCHHHHHHCC
IDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMRFLNQF
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA