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The map label for this gene is blaR1 [H]

Identifier: 126698127

GI number: 126698127

Start: 652525

End: 653907

Strand: Direct

Name: blaR1 [H]

Synonym: CD0548

Alternate gene names: 126698127

Gene position: 652525-653907 (Clockwise)

Preceding gene: 126698126

Following gene: 126698128

Centisome position: 15.21

GC content: 27.11

Gene sequence:

>1383_bases
ATGTTCATTAAATTGTTAGAAATGAGTTTTACTTCTGGAGTATTACTTTTAATAGTTATTTTTATAAGAGCATGTTTATT
TAAAAAATTACCTAAAAAGGTATTTGTATTATTGTGGTTGATTGTTTTATTTAAACTTCTAATACCAGTAAGTTTAAATT
CTGGTTTTAGTATTTATAGTATAATTGAATCGACTTTTGATGTGGAAGTGGGTAATACATCAACAGAAAATTATACTCTT
AAGAAAGCTAGTGACTCTACAGGTAAAAACAATTCTGACGAATTTGAAATAATGTCTAATATTGAAAATATTATGATGTT
GGAAATGTTGGGCATTTTGTCTTTTATAGTTACTATTATGTTTAGCATACTTTTATGCTTTAGATATTTTAAAATAATTA
ATCTTTTTAAAACTTCAATTCATATAAAAAATCATGAGTTCATTAAAAAATGGATGTGTAAGAATAGCCGTTTTAGAAGA
TTTATTGTTTGCATATCTGAATTTACTAGGACACCACTTACATCTGGTATTTTAAAACCACGAATTATTTTGCCAAAGCA
AATGAATTATGCTAATAATCAAACTTTAGACTTTGTTTTAACTCATGAAATGGTTCATATTAATAGCTTTGATAATCTGT
TAAAGTTATTTATGCTTGTAGCTCTTGTTGTCCATTGGTTTAATCCCTTAGTTTGGGTGATGTTTTTTTTACTAAATAAA
GACATAGAATTTAGTTGTGATGAAAAGGTTATGAGTATACTTGGTGAAGAATATAGGGCTGATTATGCAACCACACTAAT
AAGTCTAGCAGAGGAGAATAATCCATTTTCAATGACAATATGTAGTGGATTTGGAAAGACAAAAATAGAAAAGAGAATAG
TTAATATTATGAAATTTAAAAAATCAACTTATGTTACTTTTTTAGTTTCAACTGTATTAGTTTGTGGGACAGGTCTTGTT
TTTGCAACAGAAAATAAAGAGATTAATGAGGTTGAATCTTTTGGTTTAACAAAAAATGAACAAAGTGATAAAATTGGATT
TTCAATAAGTAGTAAATCAACTGATTTATATTCTCCCAAAGTAGAATCTGATATTCTTGTTAGTAAAGCTAAAAGTGATG
GAGAGACTCATTTTAGTACGGCAAAAGTATCTGTAATTGAATTTAGAGAGCATGAAGAATCATCTATGAGCAAAGTAACT
AATTCTGAGAATAGTGAAGAAACGTATGTAAATAAATCTAGTAATAGTAAGGATGTACTTTATACTGATTCAGGAGAAGT
TTCAATTGAGCAAAGTGGCTATAATGATAATCGCTTTGTCATATCAAGAAAAGGGAATTTGTTAGCAGTTAATAAAGAAC
AATATAGAACATGGATAGAGTAA

Upstream 100 bases:

>100_bases
GAAAAATTTCTTTCAGCTTTTATTAATAAAGAAAATCTTTCAAGTGATGAGATTACAAAACTTAAACAAATTGTTGAAAA
ATTAAAGTGAGGTAAGATTT

Downstream 100 bases:

>100_bases
CCATAAATCTTAGTAATATAAAAGATTTAGAATTAAAATACTATCTCAAAATAATTAATTTTGTTTTGAGATAGTATTTT
TTATTGAAAAGTTTTTTAAA

Product: penicillin-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLFKLLIPVSLNSGFSIYSIIESTFDVEVGNTSTENYTL
KKASDSTGKNNSDEFEIMSNIENIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFMLVALVVHWFNPLVWVMFFLLNK
DIEFSCDEKVMSILGEEYRADYATTLISLAEENNPFSMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLV
FATENKEINEVESFGLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHEESSMSKVT
NSENSEETYVNKSSNSKDVLYTDSGEVSIEQSGYNDNRFVISRKGNLLAVNKEQYRTWIE

Sequences:

>Translated_460_residues
MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLFKLLIPVSLNSGFSIYSIIESTFDVEVGNTSTENYTL
KKASDSTGKNNSDEFEIMSNIENIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFMLVALVVHWFNPLVWVMFFLLNK
DIEFSCDEKVMSILGEEYRADYATTLISLAEENNPFSMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLV
FATENKEINEVESFGLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHEESSMSKVT
NSENSEETYVNKSSNSKDVLYTDSGEVSIEQSGYNDNRFVISRKGNLLAVNKEQYRTWIE
>Mature_460_residues
MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLFKLLIPVSLNSGFSIYSIIESTFDVEVGNTSTENYTL
KKASDSTGKNNSDEFEIMSNIENIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFMLVALVVHWFNPLVWVMFFLLNK
DIEFSCDEKVMSILGEEYRADYATTLISLAEENNPFSMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLV
FATENKEINEVESFGLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHEESSMSKVT
NSENSEETYVNKSSNSKDVLYTDSGEVSIEQSGYNDNRFVISRKGNLLAVNKEQYRTWIE

Specific function: BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis [H]

COG id: COG4219

COG function: function code KT; Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460
- InterPro:   IPR008756 [H]

Pfam domain/function: PF05569 Peptidase_M56; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 52765; Mature: 52765

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLFKLLIPVSLNSGFSIYS
CEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
IIESTFDVEVGNTSTENYTLKKASDSTGKNNSDEFEIMSNIENIMMLEMLGILSFIVTIM
HHHHHHEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRRFIVCISEFTRTPLTSGILKP
HHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHCCCCC
RIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFMLVALVVHWFNPLVWVMFFLLNK
EEECCCCCCCCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DIEFSCDEKVMSILGEEYRADYATTLISLAEENNPFSMTICSGFGKTKIEKRIVNIMKFK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHH
KSTYVTFLVSTVLVCGTGLVFATENKEINEVESFGLTKNEQSDKIGFSISSKSTDLYSPK
HHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCC
VESDILVSKAKSDGETHFSTAKVSVIEFREHEESSMSKVTNSENSEETYVNKSSNSKDVL
CCCHHHHHCCCCCCCCCHHHHEEEEEEHHHHHHHHHHHHCCCCCCCHHEEECCCCCCEEE
YTDSGEVSIEQSGYNDNRFVISRKGNLLAVNKEQYRTWIE
EECCCCEEEECCCCCCCEEEEEECCCEEEECHHHHHHCCC
>Mature Secondary Structure
MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLFKLLIPVSLNSGFSIYS
CEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
IIESTFDVEVGNTSTENYTLKKASDSTGKNNSDEFEIMSNIENIMMLEMLGILSFIVTIM
HHHHHHEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRRFIVCISEFTRTPLTSGILKP
HHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHCCCCC
RIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFMLVALVVHWFNPLVWVMFFLLNK
EEECCCCCCCCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DIEFSCDEKVMSILGEEYRADYATTLISLAEENNPFSMTICSGFGKTKIEKRIVNIMKFK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHH
KSTYVTFLVSTVLVCGTGLVFATENKEINEVESFGLTKNEQSDKIGFSISSKSTDLYSPK
HHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCC
VESDILVSKAKSDGETHFSTAKVSVIEFREHEESSMSKVTNSENSEETYVNKSSNSKDVL
CCCHHHHHCCCCCCCCCHHHHEEEEEEHHHHHHHHHHHHCCCCCCCHHEEECCCCCCEEE
YTDSGEVSIEQSGYNDNRFVISRKGNLLAVNKEQYRTWIE
EECCCCEEEECCCCCCCEEEEEECCCEEEECHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040663; 3260234; 2404938 [H]