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The map label for this gene is sorA [H]

Identifier: 126698070

GI number: 126698070

Start: 582611

End: 583369

Strand: Direct

Name: sorA [H]

Synonym: CD0493

Alternate gene names: 126698070

Gene position: 582611-583369 (Clockwise)

Preceding gene: 126698069

Following gene: 126698071

Centisome position: 13.58

GC content: 34.26

Gene sequence:

>759_bases
ATGCACATTTCACTAATTCAAGCAGTATTAATAGCAATTTTTTATTATCTTTCTTGGAGTCCGTGGTTGACTTATGTTGG
ATTTTTTACATGGAATAGACCTCTATTGGCTGGATTTGTAACGGGAATTATATTAGGAGACCCTGTTCAAGGAGCAATTA
TAGGAGCAGGTATAAATATGATATATCTAGGTTTTATATCAGCAGGGGGAGCTCAGATGGGGGACCCAGCTTTTGCAGGA
TATGTAGGTACTGCTTTAGCTATAGCATCTAAGCTAGATGTAAGTACTGCAATGGCAATAGCTGTACCATTGGGAACTGT
TGCAACTGTACTTTGGATTGGAAAGATGACAGTAAATTCTTTTTTTGCACATTGGGCTGATAGAGAGGTTCAAAAAGGGA
ATGTTGATAGAGTAGCATTTATAAATATAGTACCACCACAGATACTGTTATTTGCAATGAGTTTTATACCAGCATTATTA
GTTGTTTATTTTGGTCCAAATGCGATAGATGGTATGTTGGAAGTAATGAATGATAATGTGTTACATGTATTTAATGTAAT
TGGGGCTATGTTGCCAGCACTTGGGATTGCTATGAATTTAAAATTGATTGGAAACAAGTTTACTATGCCCTTTTTCATAT
TAGGAATACTAATGGCTGTTTATTTTAAAGTAGATATAATAGTAATATCTGTTATTGGAGTAATACTTGCTCTTACAATT
ACTTCAATTAAGTACGGAAAAGATAGTGCTACATCTTAA

Upstream 100 bases:

>100_bases
TTTATACAAATAGTACCAGATGCAAAGAAAATTGATGTAGGAACATTATTGTAAAGAAGACTATCTTGTAAATCTTTAAA
AGAAAATAGGGAGGAAGAAT

Downstream 100 bases:

>100_bases
ATACATGTGAGGGGGAAAATATTATGTCAGATATAAAAAATGAAGTATCTAAGAAAACGTTAAGCAAGAAAGATGTAATA
AAATCATGGTTAAGATGGTT

Product: PTS system transporter subunit IIC

Products: protein histidine; sugar phosphate; D-glucosamine-6-phosphate [Cytoplasm]; pyruvate; glucose-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Sor; PTS system sorbose-specific EIIC component [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGIILGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAG
YVGTALAIASKLDVSTAMAIAVPLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILMAVYFKVDIIVISVIGVILALTI
TSIKYGKDSATS

Sequences:

>Translated_252_residues
MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGIILGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAG
YVGTALAIASKLDVSTAMAIAVPLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILMAVYFKVDIIVISVIGVILALTI
TSIKYGKDSATS
>Mature_252_residues
MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGIILGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAG
YVGTALAIASKLDVSTAMAIAVPLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILMAVYFKVDIIVISVIGVILALTI
TSIKYGKDSATS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3715

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI1788121, Length=251, Percent_Identity=31.0756972111554, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789528, Length=237, Percent_Identity=28.2700421940928, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004700
- InterPro:   IPR018404 [H]

Pfam domain/function: PF03609 EII-Sor [H]

EC number: NA

Molecular weight: Translated: 27041; Mature: 27041

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS51106 PTS_EIIC_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGIILGDPVQGAIIGAGINM
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEECCCHHH
IYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAVPLGTVATVLWIGKMTVNS
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALLVVYFGPNAIDGMLEVMNDNV
HHHHHHCCHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCH
LHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILMAVYFKVDIIVISVIGVILALTI
HHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSIKYGKDSATS
HHHCCCCCCCCC
>Mature Secondary Structure
MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGIILGDPVQGAIIGAGINM
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEECCCHHH
IYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAVPLGTVATVLWIGKMTVNS
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALLVVYFGPNAIDGMLEVMNDNV
HHHHHHCCHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCH
LHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILMAVYFKVDIIVISVIGVILALTI
HHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSIKYGKDSATS
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N p -phosphohistidine; sugar; phosphoenolpyruvate; glucosamine [Periplasm]; phosphoenolpyruvate; beta-D-glucose [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; fructose [Periplasm] [C]

Specific reaction: protein N p -phosphohistidine + sugar = protein histidine + sugar phosphate phosphoenolpyruvate + glucosamine [Periplasm] = D-glucosamine-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + beta-D-glucose [Periplasm] = glucose-6-phosphate [Cytoplasm]

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7947968 [H]