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The map label for this gene is sugE [H]

Identifier: 126698065

GI number: 126698065

Start: 579018

End: 579338

Strand: Direct

Name: sugE [H]

Synonym: CD0488

Alternate gene names: 126698065

Gene position: 579018-579338 (Clockwise)

Preceding gene: 126698059

Following gene: 126698067

Centisome position: 13.5

GC content: 32.09

Gene sequence:

>321_bases
ATGAAATGGTTATTTTTGTTTGTTGCAGGTTTGTTTGAAGTGTTTTGGGCTTTTCAACTAAAAAATTCACATGGATTTTC
TAAATTAACTCCAAGTATACTTACTGTTGTTGGAATGATTGTAAGTTTTTATTTTTTGTCATTAGCACTAAAACATCTTC
CACTTGGAACTTCATATGCAATATGGACTGGAATTGGTACCGTCGGTACAGCTATTGTAGGCATGGCTATTTTAAATGAG
CCTATTAGTATATCAAGAATTGCATGTATAGGTTTTATTGTGGTGGGAATTGTAGGGTTAAAGCTATTATCTACTAATTA
G

Upstream 100 bases:

>100_bases
GTGAACACGGAAGGACAAAAACCTGGGAGATATTTTATAATATTTCTCAGGTTATTTTATTGGAAAAATAAGAGACATAT
TTGAAAAGAGGGATGAATTT

Downstream 100 bases:

>100_bases
AGTATATTAATTTAAATAAGCTATGAAATTAAAGGCGAGAAAATGTTTAAAAATAATCAACATTTAAAAAGTCTTTACTT
CATAGCTTATCTTATTTATA

Product: quaternary ammonium compound-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 106

Protein sequence:

>106_residues
MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFYFLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNE
PISISRIACIGFIVVGIVGLKLLSTN

Sequences:

>Translated_106_residues
MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFYFLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNE
PISISRIACIGFIVVGIVGLKLLSTN
>Mature_106_residues
MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFYFLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNE
PISISRIACIGFIVVGIVGLKLLSTN

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=102, Percent_Identity=55.8823529411765, Blast_Score=118, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11479; Mature: 11479

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFYFLSLALKHLPLGTSYA
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
IWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKLLSTN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFYFLSLALKHLPLGTSYA
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
IWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKLLSTN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]