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The map label for this gene is mutL [H]

Identifier: 126698021

GI number: 126698021

Start: 531538

End: 532947

Strand: Direct

Name: mutL [H]

Synonym: CD0447

Alternate gene names: 126698021

Gene position: 531538-532947 (Clockwise)

Preceding gene: 126698020

Following gene: 126698022

Centisome position: 12.39

GC content: 30.85

Gene sequence:

>1410_bases
ATGGAAAATAGCAAAGTTTCTTTAAAAATAGATGTGTTGGTAGCTGAAATTGGAAGTACTACTACAGTGGTAAATGCTTT
CCACGATATTAATACTAACAATCCTATATTTTTGGGTCAAGGTCAAGCTCCAACAACAGTGTTTGAAGGTGGCGATGTAA
GAAATGGCTTATCAGGTGCTATTAAAGATTTAGCTAATAAATTATCTGTAGATGATATAGAGTATAATGATATGTTTGCA
ACTTCTAGTGCAGCTGGTGGATTAAAAATGACTGTTCATGGATTAGTCTATGATATGACAGTAAAAGCAGCTAAAGAAGC
AGCTTTAGGGGCTGGAGCTGTTATTCGTCAAATAACATCAGGTAGAATTAAAAGAACTGATTTAAATAAAATAAAAGAAA
TAAACCCAAACATAATTTTAATAGCTGGTGGAGTCGATTATGGAGAAAGAGATACAGCTATTTATAATGCAGAAATGATA
GCTTCTATGAATCTAGGCATACCAGTTATATATGCTGGTAATGTTGAAAATCAAGAGGAAATAAGGTTAATATTTGAAGA
TACTAATTATAAGCTTTATATAACTGAAAATGTATACCCTAAAATAGATTTATTGAATATAGAACCTACAAGAAGAATCA
TTCAAAGTGTATTTGAAGAACACATAACTACAGCACCAGGAATGAAATACATTAAAGAAATGGTTAATGAAAATATTACT
CCAACCCCAGGAGCTGTAATGGAAGCTTCTAAACTTTTATATAAAAATATTGGAGATTTATTAACTCTGGATGTAGGTGG
AGCAACTACTGATGTACATTCTGTTACAGATGGAAGTGACTATATTAATAAAATTTTGGTTAATCCTGAACCTACTGCAA
AGAGAAGTGTTGAGGGGGATTTAGGTGTATATGTAAATATGAAGAATATAGTAGAAGTTATAGGTAAAGAAAACTTACAA
AGTGAACTATCTATAGATATTGATGCAGTAATAGAGAATTATCCTCCAATACCAAAATCAAAAGAAGAAATATTATTTGT
TGAGAGGTTGACAAAAGAAGCTGTTGTTAAAGCTATGCTAAGACATTCAGGAAAAATAAGAAATATCTATGGAACAACTG
GAAAAGTCAAAATTGCAGAAGGGAAAGATTTAACAGAAGTAAGATATATAGTTGGTACAGGGGGAGCACTTACTAGGCTC
CCTAGTAGAATTGAAATATTAGATAATATGCTCAAATACAATAAAAATAATGAATTACTATTTCCAAAGGAAAAAACAAA
GATATTAATAGATAATGACTATATTATGGCATCTATGGGTGTTTTATCTAAAAAATATGAAGAAGCATCTCTTAAGCTCC
TGTTAAAAAGTTTGAATTTTGAGGAGGAAAGATTATGTATCCTAGGTTAG

Upstream 100 bases:

>100_bases
CTGTTGAACAAGGCATAGATGCTGGATTTGGAAGAAACAGCAAAGGCATACATGTAGCCACTTTCTTAGTTGAAAAAAGA
AGAGAAATGAGTAATAAATA

Downstream 100 bases:

>100_bases
AAATAGATATAGAAAAGTTAAAGCATAATGTAAAATTAATTTCGCAGATGTGTCATGAAAGAAATATTAAGATATCTTTT
GTTACTAAATCATTTTGTGC

Product: component of D-ornithine aminomutase

Products: L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAPTTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFA
TSSAAGGLKMTVHGLVYDMTVKAAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVFEEHITTAPGMKYIKEMVNENIT
PTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVTDGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQ
SELSIDIDAVIENYPPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVGTGGALTRL
PSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEASLKLLLKSLNFEEERLCILG

Sequences:

>Translated_469_residues
MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAPTTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFA
TSSAAGGLKMTVHGLVYDMTVKAAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVFEEHITTAPGMKYIKEMVNENIT
PTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVTDGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQ
SELSIDIDAVIENYPPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVGTGGALTRL
PSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEASLKLLLKSLNFEEERLCILG
>Mature_469_residues
MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAPTTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFA
TSSAAGGLKMTVHGLVYDMTVKAAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVFEEHITTAPGMKYIKEMVNENIT
PTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVTDGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQ
SELSIDIDAVIENYPPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVGTGGALTRL
PSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEASLKLLLKSLNFEEERLCILG

Specific function: May play a role in glutamate fermentation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006230
- InterPro:   IPR002821 [H]

Pfam domain/function: PF01968 Hydantoinase_A [H]

EC number: 5.4.99.1

Molecular weight: Translated: 51636; Mature: 51636

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAPTTVFEGGDVRNGLSGA
CCCCEEEEEEEEEEEECCCCEEEEEHHHCCCCCCCEEEECCCCCCEEECCCCCCCCHHHH
IKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVKAAKEAALGAGAVIRQITS
HHHHHHHCCCCCCCCCCEEECCCCCCCEEEEEEHEEEEHHHHHHHHHHCCHHHHHHHHHC
GRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMIASMNLGIPVIYAGNVENQEE
CCEEECHHHHHHHCCCCEEEEECCCCCCCCCCEEEEHHEEEEECCCEEEEEECCCCCCCE
IRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVFEEHITTAPGMKYIKEMVNENIT
EEEEEECCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
PTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVTDGSDYINKILVNPEPTAKRSVEGD
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHEEEECCCCCCCCCCCCC
LGVYVNMKNIVEVIGKENLQSELSIDIDAVIENYPPIPKSKEEILFVERLTKEAVVKAML
CEEEEEHHHHHHHHCCCCCHHHHCEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVGTGGALTRLPSRIEILDNMLKYNKNNELL
HCCCCEEEEECCCCEEEEECCCCCCEEEEEEECCHHHHHCCHHHHHHHHHHHHCCCCCEE
FPKEKTKILIDNDYIMASMGVLSKKYEEASLKLLLKSLNFEEERLCILG
CCCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure
MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAPTTVFEGGDVRNGLSGA
CCCCEEEEEEEEEEEECCCCEEEEEHHHCCCCCCCEEEECCCCCCEEECCCCCCCCHHHH
IKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVKAAKEAALGAGAVIRQITS
HHHHHHHCCCCCCCCCCEEECCCCCCCEEEEEEHEEEEHHHHHHHHHHCCHHHHHHHHHC
GRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMIASMNLGIPVIYAGNVENQEE
CCEEECHHHHHHHCCCCEEEEECCCCCCCCCCEEEEHHEEEEECCCEEEEEECCCCCCCE
IRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVFEEHITTAPGMKYIKEMVNENIT
EEEEEECCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
PTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVTDGSDYINKILVNPEPTAKRSVEGD
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHEEEECCCCCCCCCCCCC
LGVYVNMKNIVEVIGKENLQSELSIDIDAVIENYPPIPKSKEEILFVERLTKEAVVKAML
CEEEEEHHHHHHHHCCCCCHHHHCEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVGTGGALTRLPSRIEILDNMLKYNKNNELL
HCCCCEEEEECCCCEEEEECCCCCCEEEEEEECCHHHHHCCHHHHHHHHHHHHCCCCCEE
FPKEKTKILIDNDYIMASMGVLSKKYEEASLKLLLKSLNFEEERLCILG
CCCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-threo-3-methylaspartate

Specific reaction: L-threo-3-methylaspartate = L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8428631 [H]