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The map label for this gene is etfA1 [H]

Identifier: 126697970

GI number: 126697970

Start: 473457

End: 474494

Strand: Direct

Name: etfA1 [H]

Synonym: CD0401

Alternate gene names: 126697970

Gene position: 473457-474494 (Clockwise)

Preceding gene: 126697969

Following gene: 126697971

Centisome position: 11.04

GC content: 33.53

Gene sequence:

>1038_bases
ATGAATGATATAAAAGATTTAAGTTCTTATAAAAACGTATGGATATTTGCAGAACAAAGAGAAGGAAAAATAGCTCCAGT
AGTTATAGAATTATTAGGAGAAGGAAGAAAATTAGCTAAAGAAGTAGATGCAGAACTTTGTGCAATATTATTAGGAAAAG
ATGTTGATGGATTAGCTAAAGAATTAATCACTTTTGGAGCTGACAAAGTTTATGTTGCAGATGATGCTCTTTTAGAAAAA
TATACAACTGATGCATATACAAAAGTAATAAAAGATGCAATAGATGAAATAAAACCAGAAATAATGCTTTTCGGAGCAAC
TCATATAGGTAGAGACTTAGCACCTAGAATAGCTTCAAGAGTTGGAACTGGATTAACAGCTGACTGTACTAAGTTAGAAA
TAGACCCAGAAGATAAGAAAATAAAACAAACTCGTCCAGCATTTGGTGGAAACATAATGGCTACAATCATTTGTCCAAAC
CATAGACCTCAAATGTCTACAGTTAGACCTGGTGTTATGGATAAAGCTGAAAAAGACGAAACAAGAACTGGTGAAGTTAT
AGCATTAGACTACAAAATAACTCAAGATGATATAAGAACTACTGTTTTAGAAACAGTTAAAACTAAGAAAGATTTAGTAT
CTCTTACAGATGCAAATGTTATAGTATCAGGTGGTCTAGGATTAGGTGGACCAGAAGGATTTGAAATGCTTAAGAAATTA
GCTGACAAATTAGGTGGAGTAGTTGGTTCTTCTCGTGCGGCTGTTGATGCTGGATGGATAGACCATTCTCACCAAGTAGG
TCAAACAGGAACTACTGTTAAACCAAACCTATATATAGCTTGTGGTATATCAGGAGCAATACAACATTTAGCAGGTATGC
AATCATCAGATTTCATAATTGCTATAAACAAAAACCCAGCAGCTCCAATTTTAGAAATCGCTGACTATGGAGTAGTTGGA
GACTTACATGAAATAGTTCCAATGCTTATAGAAAAATTAGATAGCGTTGATGATTTATTAGAAGCTATAAAAGCTTAA

Upstream 100 bases:

>100_bases
AAAAGGAGAAATCTTAGAAGGTAAAGCTGATGAAATAGCTAGTAAAATAATAATCGGTCTAAAACAAAAGCACATTATAT
AAGTTGGAGGAGTACAAACT

Downstream 100 bases:

>100_bases
TAGATACAAACTATATAAATATTACTGATTGAATAAGTCTTATTAGTTAGTAACATAATTATTAACCCTTTGATAAGTTA
TTGCTAGTGTGTATTTGTCA

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDAELCAILLGKDVDGLAKELITFGADKVYVADDALLEK
YTTDAYTKVIKDAIDEIKPEIMLFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDANVIVSGGLGLGGPEGFEMLKKL
ADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPNLYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVG
DLHEIVPMLIEKLDSVDDLLEAIKA

Sequences:

>Translated_345_residues
MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDAELCAILLGKDVDGLAKELITFGADKVYVADDALLEK
YTTDAYTKVIKDAIDEIKPEIMLFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDANVIVSGGLGLGGPEGFEMLKKL
ADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPNLYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVG
DLHEIVPMLIEKLDSVDDLLEAIKA
>Mature_345_residues
MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDAELCAILLGKDVDGLAKELITFGADKVYVADDALLEK
YTTDAYTKVIKDAIDEIKPEIMLFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDANVIVSGGLGLGGPEGFEMLKKL
ADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPNLYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVG
DLHEIVPMLIEKLDSVDDLLEAIKA

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=329, Percent_Identity=35.5623100303951, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI189181759, Length=268, Percent_Identity=39.1791044776119, Blast_Score=164, Evalue=1e-40,
Organism=Escherichia coli, GI1786226, Length=335, Percent_Identity=28.955223880597, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1787990, Length=331, Percent_Identity=29.3051359516616, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082157, Length=245, Percent_Identity=25.3061224489796, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17506929, Length=335, Percent_Identity=34.9253731343284, Blast_Score=164, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6325261, Length=334, Percent_Identity=33.2335329341317, Blast_Score=157, Evalue=2e-39,
Organism=Drosophila melanogaster, GI17136898, Length=338, Percent_Identity=33.4319526627219, Blast_Score=171, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24652801, Length=338, Percent_Identity=33.4319526627219, Blast_Score=171, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 37148; Mature: 37148

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDAELCAILLGKDVDGLAK
CCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHH
ELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIMLFGATHIGRDLAPRIASR
HHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHCHHHHHHHHHH
VGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPNHRPQMSTVRPGVMDKAEKDE
HCCCCCCCCEEEEECCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCC
TRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDANVIVSGGLGLGGPEGFEMLKKL
CCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
ADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPNLYIACGISGAIQHLAGMQSSDFII
HHHHCCCCCCCCCCEECCCCCCCCCCCCCCCEECCCEEEEECCHHHHHHHHCCCCCCEEE
AINKNPAAPILEIADYGVVGDLHEIVPMLIEKLDSVDDLLEAIKA
EECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDAELCAILLGKDVDGLAK
CCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHH
ELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIMLFGATHIGRDLAPRIASR
HHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHCHHHHHHHHHH
VGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPNHRPQMSTVRPGVMDKAEKDE
HCCCCCCCCEEEEECCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCC
TRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDANVIVSGGLGLGGPEGFEMLKKL
CCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
ADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPNLYIACGISGAIQHLAGMQSSDFII
HHHHCCCCCCCCCCEECCCCCCCCCCCCCCCEECCCEEEEECCHHHHHHHHCCCCCCEEE
AINKNPAAPILEIADYGVVGDLHEIVPMLIEKLDSVDDLLEAIKA
EECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA