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The map label for this gene is htpG [H]

Identifier: 126697845

GI number: 126697845

Start: 333418

End: 335355

Strand: Direct

Name: htpG [H]

Synonym: CD0273

Alternate gene names: 126697845

Gene position: 333418-335355 (Clockwise)

Preceding gene: 126697844

Following gene: 126697846

Centisome position: 7.77

GC content: 27.81

Gene sequence:

>1938_bases
ATGGAATTTGAAAAAGGGAGTATTTCAATTCATACAGAAAATATTTTTCCTATAATTAAAAAATGGTTATACTCTGATAA
AGACATATTTATAAGAGAGCTTATAAGTAATGGATGTGATGCAGTAAGTAAACATAAAAGACTTGTATCACTAGGAGAAA
TATCAGAAAATAAGTCATCAGATTATAAAATTACAGTATCTGTAAATAAAGGAGAAGGTACACTTAAATTTATTGACAAT
GGAATTGGTATGACTGAAGAAGAGATAAAAAAATACATAAATCAAGTTGCTTTTTCAGGTGCTGAAGATTTCTTTAATAA
ATATAAGGATAAAATGGAAGAGTCAAATGATATAATAGGTCATTTTGGATTAGGATTTTATTCTGCATTTATGGTGTCTA
AAAAGGTACAAATAGATACACTTTCATATACAGAAGGAGCGACTCCTGTAAGATGGATATCTGAAGGTGGTACAGAATAC
GAAATATCTGAATCAGATGCTAGAAATGATAGAGGAACTACTATAACACTATTTATTGATGATGATAGTAAAGAATTTTT
AGATGAATTTACTGTAAGAGGAATAATAAATAAATACTGTTCTTTCTTACCAGTAGAAATATATTTAGAAGATGTTGAAA
GATTAGAAAGAGAAGCTAAAGAAGCAGAAGAAAAAGCTAAAAAACAAAAGGAAGATGGAAAAGAAGAGATTGTAGATGCA
AAAGTAATTGAGCCTTTAAACGACACTAATCCTCTATGGTTAAAATCTCCAAAAGACTGTACTGATGAGGAGTATAAAGA
GTTTTATAGAAAGGTATTCAATGTATTTGATGAACCTTTATTTTGGATACATTTAAATGTAGATTATCCTTTCAATTTAA
AGGGTATACTTTACTTCCCTAAATTAAAAAATGAGTTTGAACTGACTGAAGGAAAAGTAAAATTATACAACAATCAAGTG
TTTGTGGCTGACAATATAAAAGAAGTTATACCAGAATTTTTACTTTTATTAAAAGGAGTTATAGACTGCCCAGACTTACC
ATTAAATGTATCAAGAAGTTTCTTACAAAATGACAGGGATGTAAGCAAAATTTCTAAACATATAATTAAAAAAGTAGCTG
ATAAGTTGAAATCTCTTTGTAAAAATGAAAGAGAAGAATACAATAAGTTTTGGGATGATATACAAATATTTATTAAATAT
GGTTGCTTAAAAGATGAAAGTTTCTATGAGAAGGTAAAAGAATGTATATTATTCAAAACTATTGATGATGAGTATATAAC
ATTACAAGATTATTTAGAAAAATGTAAGGACAAACATGAAAATAAGGTATTTTATGTAAGTGATAAGGAACAGCAATCTC
AATACATTAAACTATTTAAAGAATACGACTTAAGTGCTGTTGTTTTAAACTCATCAATAGATACTCATTTTATTTCATTT
ATGGAATATAAAGAGAATGGAGTTAAGTTTAATAGAATAGATGCAGACCTTTCTGATGTATTAAAAGATAAAAATGAAAA
TAAAGATAGTGAAGAAAACAAAGAAGAGATAGCTAAGATAGAAGGTCTGTTTAAAGAAGCTGTCGGAGAAAGAGTGAAGA
ATTATTCTGTAGAAGGATTGAAAAATGAAGACACTCCAGCTATGGTATTAGTATCAGAACAATCTATTAGAATGGCAGAA
ATGCAGTCAAGATTTGCTGGAATGGATTTAGGAATGAATTTTGAGGAAGAAAAAACTCTTGTAATAAATGAGAACAGTCC
AATAATCAAAAAATTGGTTTCTCTTAAAGATGATGAGGAAAAGAAAGATAAGATTACGCTTATTTGTAACCAGATAGCAG
ATTTAGCTTTACTTTCTAATAAAGAATTAAAGCCAGATGAGTTAGATTCATTTGTACAAAGAAGTAATAAGCTTATGAGT
CTTTTGATAGAATTATAA

Upstream 100 bases:

>100_bases
AAAATAAATTATTTTATTTTAAAATAATATGATTATAATATATTGACATACCATTTTAAAAAATTTAAAATATTAATTAT
AAAATGAGGAGGGATAAAAA

Downstream 100 bases:

>100_bases
GATTGAATTTGAATACATTGAAGCAAATTTATAAAAAGTATTCAATATCAGTGATGAGAAAGAAGTGTCTCAAAATGAAC
TTTTCAGTTCATGAGGCGCT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSKHKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDN
GIGMTEEEIKKYINQVAFSGAEDFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLEREAKEAEEKAKKQKEDGKEEIVDA
KVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVFDEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQV
FVADNIKEVIPEFLLLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWDDIQIFIKY
GCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKEQQSQYIKLFKEYDLSAVVLNSSIDTHFISF
MEYKENGVKFNRIDADLSDVLKDKNENKDSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAE
MQSRFAGMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELKPDELDSFVQRSNKLMS
LLIEL

Sequences:

>Translated_645_residues
MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSKHKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDN
GIGMTEEEIKKYINQVAFSGAEDFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLEREAKEAEEKAKKQKEDGKEEIVDA
KVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVFDEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQV
FVADNIKEVIPEFLLLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWDDIQIFIKY
GCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKEQQSQYIKLFKEYDLSAVVLNSSIDTHFISF
MEYKENGVKFNRIDADLSDVLKDKNENKDSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAE
MQSRFAGMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELKPDELDSFVQRSNKLMS
LLIEL
>Mature_645_residues
MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSKHKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDN
GIGMTEEEIKKYINQVAFSGAEDFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLEREAKEAEEKAKKQKEDGKEEIVDA
KVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVFDEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQV
FVADNIKEVIPEFLLLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWDDIQIFIKY
GCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKEQQSQYIKLFKEYDLSAVVLNSSIDTHFISF
MEYKENGVKFNRIDADLSDVLKDKNENKDSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAE
MQSRFAGMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELKPDELDSFVQRSNKLMS
LLIEL

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=663, Percent_Identity=26.8476621417798, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI4507677, Length=685, Percent_Identity=26.8613138686131, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI20149594, Length=512, Percent_Identity=29.6875, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI154146191, Length=246, Percent_Identity=30.8943089430894, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI153792590, Length=246, Percent_Identity=30.8943089430894, Blast_Score=134, Evalue=3e-31,
Organism=Escherichia coli, GI1786679, Length=639, Percent_Identity=29.5774647887324, Blast_Score=262, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI17542208, Length=628, Percent_Identity=27.5477707006369, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI115535205, Length=676, Percent_Identity=25.887573964497, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17559162, Length=492, Percent_Identity=29.8780487804878, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI115535167, Length=442, Percent_Identity=28.7330316742081, Blast_Score=197, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6325016, Length=679, Percent_Identity=28.8659793814433, Blast_Score=231, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6323840, Length=675, Percent_Identity=28.8888888888889, Blast_Score=231, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24586016, Length=639, Percent_Identity=29.4209702660407, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI17647529, Length=673, Percent_Identity=28.2317979197623, Blast_Score=234, Evalue=2e-61,
Organism=Drosophila melanogaster, GI21357739, Length=636, Percent_Identity=28.4591194968553, Blast_Score=226, Evalue=4e-59,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 74924; Mature: 74924

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00280 BPTI_KUNITZ_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSKHKRLVSLGEISENKSS
CCCCCCCEEEEECHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
DYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAEDFFNKYKDKMEESNDIIG
CEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEE
HFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEYEISESDARNDRGTTITLFID
HHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHCCCCCEEEECCCCCCCCCCCEEEEEEE
DDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLEREAKEAEEKAKKQKEDGKEEIVDA
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVFDEPLFWIHLNVDYPFNLKGILYFP
HHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEC
KLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFLLLLKGVIDCPDLPLNVSRSFLQNDRD
CCCCCCEECCCEEEEECCEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC
VSKISKHIIKKVADKLKSLCKNEREEYNKFWDDIQIFIKYGCLKDESFYEKVKECILFKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEE
IDDEYITLQDYLEKCKDKHENKVFYVSDKEQQSQYIKLFKEYDLSAVVLNSSIDTHFISF
CCCCEEEHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHH
MEYKENGVKFNRIDADLSDVLKDKNENKDSEENKEEIAKIEGLFKEAVGERVKNYSVEGL
HHHHHCCCEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KNEDTPAMVLVSEQSIRMAEMQSRFAGMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEE
CCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCH
KKDKITLICNQIADLALLSNKELKPDELDSFVQRSNKLMSLLIEL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSKHKRLVSLGEISENKSS
CCCCCCCEEEEECHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
DYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAEDFFNKYKDKMEESNDIIG
CEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEE
HFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEYEISESDARNDRGTTITLFID
HHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHCCCCCEEEECCCCCCCCCCCEEEEEEE
DDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLEREAKEAEEKAKKQKEDGKEEIVDA
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVFDEPLFWIHLNVDYPFNLKGILYFP
HHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEC
KLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFLLLLKGVIDCPDLPLNVSRSFLQNDRD
CCCCCCEECCCEEEEECCEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC
VSKISKHIIKKVADKLKSLCKNEREEYNKFWDDIQIFIKYGCLKDESFYEKVKECILFKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEE
IDDEYITLQDYLEKCKDKHENKVFYVSDKEQQSQYIKLFKEYDLSAVVLNSSIDTHFISF
CCCCEEEHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHH
MEYKENGVKFNRIDADLSDVLKDKNENKDSEENKEEIAKIEGLFKEAVGERVKNYSVEGL
HHHHHCCCEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KNEDTPAMVLVSEQSIRMAEMQSRFAGMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEE
CCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCH
KKDKITLICNQIADLALLSNKELKPDELDSFVQRSNKLMSLLIEL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11807048 [H]