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The map label for this gene is blaR1 [H]

Identifier: 126697754

GI number: 126697754

Start: 239189

End: 240322

Strand: Direct

Name: blaR1 [H]

Synonym: CD0181

Alternate gene names: 126697754

Gene position: 239189-240322 (Clockwise)

Preceding gene: 126697753

Following gene: 126697755

Centisome position: 5.58

GC content: 23.37

Gene sequence:

>1134_bases
ATGTCTAACTTTATTCTAAATGGGATTTTTAGAACAGTTATAGTAAGTAGTCTAAGCATTCTTCTGATATTGATTTTCAA
GAAAAATGTATTTAAAAGATTTAGCAAAAAATTTAATTATTATATATGGATGATAGTTGTTATTAAATTATTTTTACCAT
TTACATATTATACTTTTACAATAAATATCTTGAGAAGTAAAAAACACATTAATATTAATAACATAAATTTAGAGGGATTT
AATAATGTTTCAACTATAAGTAATAATATTATATTGTACACTTGGATTATAACTGTAGTAGTGTATTTAATTTACACTAT
ATTTAAATATATAAAACTTAAAAATTTAATAAATGACTTATCTTATGATGTTGATGATAGAGAGATTGTAAATCTTTATA
AAAATATATTAGAAGAATTTAATATAACAAAAGATATAAAACTCAAATACTCTTATGAAGTTGAAACACCAGCATTTTTT
AATTCATGTGTGCTTTTGCCACCACATGAGTATAAATTGAAAGAGTTAGACTGGATTTTTAGACATGAGCTTATGCATTT
TAAGAGTAGGGACCTTTATTTAAAGTATGTAATCCTGTTTTTAAAAACAGTATATTGGTTTAATCCATTTATATATATAA
TGGATAAACATATAGATTTAGATTGTGAACTTTATTGTGATGAAAGAGTTTTAAAAAATCGAAATTCAGAGGAAAAAAAG
GATTATGCTTTAACAATTCTAAATGCAATGAGAAAAGGTTCAAATACTTCAAATAAATTTATAGCTGGACTTCATAAGCA
ATCTGATATTAAAAAGAGAGTTATGAATATGTTTAATGAAAAGTACAAGAATGGTATATTAATGGCATTAACTTTATGTT
TATTATCTTCTATTACTTTTTTGAAGGTTAATTCAACTAGTATTGTTAATCTTAATGTATTACCTAAAGGATTTGAAGAC
TTACGAACTGTTAGCAGTATACGTTTTTCAGTTATAGGATTTACATATGCAGATGCTCCTAAAAATATGAGGGAAGAATA
TAAAATAAATTGTGAATCATTAGGTTTGATACCTAAAGACTCTGATAAAATAGAAGTTGGTATAGAATATTATGACAGTC
TATTGAATGATTAA

Upstream 100 bases:

>100_bases
CAAAAAATGTATCTTTTTAATAAATAAAGATAATATGAAAACTTAAAAGGTAAATAAACTTAAATATAAAATACTCTTAA
ATAAGGTAGGAGAAAAATGT

Downstream 100 bases:

>100_bases
ATAAATATTATTTTAACAGATATTAATTATAAAGTTTTGAATAGTAATTTGTTGAGAAATAAATATATCCTTATAAAAAT
AGATACTTATATACCAAGAA

Product: membrane-associated metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWMIVVIKLFLPFTYYTFTINILRSKKHININNINLEGF
NNVSTISNNIILYTWIITVVVYLIYTIFKYIKLKNLINDLSYDVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHIDLDCELYCDERVLKNRNSEEKK
DYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMNMFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNVLPKGFED
LRTVSSIRFSVIGFTYADAPKNMREEYKINCESLGLIPKDSDKIEVGIEYYDSLLND

Sequences:

>Translated_377_residues
MSNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWMIVVIKLFLPFTYYTFTINILRSKKHININNINLEGF
NNVSTISNNIILYTWIITVVVYLIYTIFKYIKLKNLINDLSYDVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHIDLDCELYCDERVLKNRNSEEKK
DYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMNMFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNVLPKGFED
LRTVSSIRFSVIGFTYADAPKNMREEYKINCESLGLIPKDSDKIEVGIEYYDSLLND
>Mature_376_residues
SNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWMIVVIKLFLPFTYYTFTINILRSKKHININNINLEGFN
NVSTISNNIILYTWIITVVVYLIYTIFKYIKLKNLINDLSYDVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFFN
SCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHIDLDCELYCDERVLKNRNSEEKKD
YALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMNMFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNVLPKGFEDL
RTVSSIRFSVIGFTYADAPKNMREEYKINCESLGLIPKDSDKIEVGIEYYDSLLND

Specific function: BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis [H]

COG id: COG4219

COG function: function code KT; Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460
- InterPro:   IPR008756 [H]

Pfam domain/function: PF05569 Peptidase_M56; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 44651; Mature: 44520

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWMIVVIKLFLPFTYYTFT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEE
INILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVYLIYTIFKYIKLKNLINDL
EEEEECCCEECEEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYDVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFFNSCVLLPPHEYKLKELDWIF
CCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCHHHCCEEEECCCCCHHHHHHHHH
RHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHIDLDCELYCDERVLKNRNSEEKK
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEECHHHHCCCCCCHHH
DYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMNMFNEKYKNGILMALTLCLLSSITF
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEE
LKVNSTSIVNLNVLPKGFEDLRTVSSIRFSVIGFTYADAPKNMREEYKINCESLGLIPKD
EEECCCEEEEEEECCCCHHHHHHHHHHHHHEEEEEECCCCHHHHHHHCCCHHHCCCCCCC
SDKIEVGIEYYDSLLND
CCCEEEEHHHHHHHHCC
>Mature Secondary Structure 
SNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWMIVVIKLFLPFTYYTFT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEE
INILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVYLIYTIFKYIKLKNLINDL
EEEEECCCEECEEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYDVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFFNSCVLLPPHEYKLKELDWIF
CCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCHHHCCEEEECCCCCHHHHHHHHH
RHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHIDLDCELYCDERVLKNRNSEEKK
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEECHHHHCCCCCCHHH
DYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMNMFNEKYKNGILMALTLCLLSSITF
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEE
LKVNSTSIVNLNVLPKGFEDLRTVSSIRFSVIGFTYADAPKNMREEYKINCESLGLIPKD
EEECCCEEEEEEECCCCHHHHHHHHHHHHHEEEEEECCCCHHHHHHHCCCHHHCCCCCCC
SDKIEVGIEYYDSLLND
CCCEEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040663; 3260234; 2404938 [H]