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The map label for this gene is grdB [H]

Identifier: 126697710

GI number: 126697710

Start: 184689

End: 185207

Strand: Direct

Name: grdB [H]

Synonym: CD0138

Alternate gene names: 126697710

Gene position: 184689-185207 (Clockwise)

Preceding gene: 126697709

Following gene: 126697711

Centisome position: 4.3

GC content: 30.06

Gene sequence:

>519_bases
ATGAAGAAAATAGTGATGATATTGGACCAAATACAAGCTGGAGCTGGAGGAAAAGAGAAAAGTAATATACCTCCTGCTGG
AAAATCAAGCCCATTAGGACCAGGTGTAATGATGGATCCATTTTTAAATGAATCTAAGGTAATAGCTACCTTATTTTGTG
GGGATGAATTTTTTGTAAATAATCAAGAAGAAGTAACGAGTAAGATGATAGCTATGGTAAAAAAATTAAACCCTGATGTA
GTAATCTGTGGACCAAGCTTTAATTACGAAAACTTTTCTAAGATGTCAGCAATACTGTCTAAAAATATAAATGATAAAAC
AGATATACCAGCTTTTGCAGCTATGTCAGAAGAAAATATAGATGTGATAAACGAATATAAAAATGACATATGTATAGTTA
AGACTCCAAAAAAAGGTGGAATTGGTCTTAATGATTCATTAAATAACATATGTAAATTGGCAAAAGCAATAGCAAATAAA
GAAGATATAACTTTGATGAAAGAAGAATTTTGTTATTAA

Upstream 100 bases:

>100_bases
AAAATACTAGACAAACAATATTTAAAAGACGAAAAATCAAATGTTGCAGAGGAAGATGATGATATATCTTTTGATGATTT
AGTATTATAGGAGGAAGATT

Downstream 100 bases:

>100_bases
TAAGAGTATTAATTATTAGCAAGTTTAAATATTATACTATTTATAATAAGCATACATTAGTAAAATCTATATAATTTAAG
GAGGGGAATTTTAACATGTG

Product: hypothetical protein

Products: NA

Alternate protein names: Selenoprotein PB gamma [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMDPFLNESKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDV
VICGPSFNYENFSKMSAILSKNINDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
EDITLMKEEFCY

Sequences:

>Translated_172_residues
MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMDPFLNESKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDV
VICGPSFNYENFSKMSAILSKNINDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
EDITLMKEEFCY
>Mature_172_residues
MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMDPFLNESKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDV
VICGPSFNYENFSKMSAILSKNINDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
EDITLMKEEFCY

Specific function: In the first step of glycine reductase, the substrate is bound to component PB via a Schiff base intermediate. Then the PB- activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated seleno

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the grdB/grdF/grdH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010186
- InterPro:   IPR022787
- InterPro:   IPR010187 [H]

Pfam domain/function: PF07355 GRDB [H]

EC number: =1.21.4.2 [H]

Molecular weight: Translated: 18833; Mature: 18833

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMDPFLNESKVIATLFCGDEFFVN
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEEEECCCCEEC
NQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKNINDKTDIPAFAAMSEENI
CHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCCC
DVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANKEDITLMKEEFCY
HHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMDPFLNESKVIATLFCGDEFFVN
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEEEECCCCEEC
NQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKNINDKTDIPAFAAMSEENI
CHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCCC
DVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANKEDITLMKEEFCY
HHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA