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The map label for this gene is licC [H]

Identifier: 126697709

GI number: 126697709

Start: 183344

End: 184678

Strand: Direct

Name: licC [H]

Synonym: CD0137

Alternate gene names: 126697709

Gene position: 183344-184678 (Clockwise)

Preceding gene: 126697708

Following gene: 126697710

Centisome position: 4.27

GC content: 30.79

Gene sequence:

>1335_bases
ATGAATAGATTGGAAAGAATACTTATGCCATTGGCTGAAAAAATAGGTAAAAATAAATTATTAATTGCAATTAGAGATGG
TTTTTTAGTATCATCACCATTATTAATAATAGGTTCATTATTTTTATTAGTAGCAAATTTTCCTATAAAAGGATGGAATG
AATTTGTAGGTCAAATTTTTGGTCCAGATTGGGCTGTAAAATTGCAACAACCAACTGTAGCAACATTTGAAGTAATGACT
CTACTTGCAGTTTTAGGGATTGGATATTCTTATGCAAAGCAAATAGATGTAGACCCAATAGCATCAGCAGCAGTTGCAAT
AGTTGCCTTTTTTATAATAACACCATTTGTAATACCATATACACCAGAAGGAACAGAATCAGTTTACATGGTAACAGGTA
TACCACTAGGTTGGATGGGTTCTAAGGGAATGTTTGTAGGTATGATAACAGCAATAACCTCTGTAAAATTATTTGCTGCA
GTTGTAAAAAAAGGATGGACATTGAAAATGCCAGATGGAGTTCCTCCAACTGTATCAAAATCATTTGCAGCATTAATACC
AAGTGCAATAGTTATGGTAGTTTTCTTTTTAGTTAAGATAGCTTTTGAAGCTACACCATATGGAAATGTACATGAATTTA
TATTTAATTTTTTACAAATACCATTATTAAAATTAGGAAATACTTTAAGCGCTACAGCAATTGCTTATGTATTCTTACAT
CTATTCTGGTTCTTTGGAATAAATGGAAGTAGTGTTGTTGGAGCTGTGTATAATCCAATATTAAAAATTCTATCAGCTGA
AAACTTAGCTGCTTTTCAAGCTGGTACAAAACTACCAAACATAATAACTGCTCAATTTCAAGATATGTTTGCAACATTTG
GTGGGGCAGGTAGTACATTATCATTAATTATAGCTATGTTATTAATATGTAAAAGTAAACGTATAAAATCAATAGGAAAA
TTATCAATTTTACCAGGTATATTTGGTATAAATGAGCCATTGATATTTGGTCTACCGATAATGCTTAATCCATTGCTATT
GATACCATTTGCATTAGTTCCAACAGTAAATATAATAATAGCTTATTTCTGTATGTCAACAGGATTAGTACCACTTACAA
ATGGAGTTCAGCTACCGTGGACAACTCCAATTATATTCTCTGGATTTCTAACAACGGGATGGCAAGGGGCAGTTTTACAA
TTAGTACTTCTTATACTAGGAATATTTATGTATATACCATTTATAAAAATACTAGACAAACAATATTTAAAAGACGAAAA
ATCAAATGTTGCAGAGGAAGATGATGATATATCTTTTGATGATTTAGTATTATAG

Upstream 100 bases:

>100_bases
CTATGAATGGGGAAAAAGTATTAAAGCTTGCTATAAAGCTAATAAAATCTAAGCAAGCGTAGAATTATAGTAAAAAATAA
TAGGAAATGAGGGTGGATAG

Downstream 100 bases:

>100_bases
GAGGAAGATTATGAAGAAAATAGTGATGATATTGGACCAAATACAAGCTGGAGCTGGAGGAAAAGAGAAAAGTAATATAC
CTCCTGCTGGAAAATCAAGC

Product: PTS system transporter subunit IIC

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLVANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMT
LLAVLGIGYSYAKQIDVDPIASAAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGNVHEFIFNFLQIPLLKLGNTLSATAIAYVFLH
LFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGTKLPNIITAQFQDMFATFGGAGSTLSLIIAMLLICKSKRIKSIGK
LSILPGIFGINEPLIFGLPIMLNPLLLIPFALVPTVNIIIAYFCMSTGLVPLTNGVQLPWTTPIIFSGFLTTGWQGAVLQ
LVLLILGIFMYIPFIKILDKQYLKDEKSNVAEEDDDISFDDLVL

Sequences:

>Translated_444_residues
MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLVANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMT
LLAVLGIGYSYAKQIDVDPIASAAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGNVHEFIFNFLQIPLLKLGNTLSATAIAYVFLH
LFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGTKLPNIITAQFQDMFATFGGAGSTLSLIIAMLLICKSKRIKSIGK
LSILPGIFGINEPLIFGLPIMLNPLLLIPFALVPTVNIIIAYFCMSTGLVPLTNGVQLPWTTPIIFSGFLTTGWQGAVLQ
LVLLILGIFMYIPFIKILDKQYLKDEKSNVAEEDDDISFDDLVL
>Mature_444_residues
MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLVANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMT
LLAVLGIGYSYAKQIDVDPIASAAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGNVHEFIFNFLQIPLLKLGNTLSATAIAYVFLH
LFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGTKLPNIITAQFQDMFATFGGAGSTLSLIIAMLLICKSKRIKSIGK
LSILPGIFGINEPLIFGLPIMLNPLLLIPFALVPTVNIIIAYFCMSTGLVPLTNGVQLPWTTPIIFSGFLTTGWQGAVLQ
LVLLILGIFMYIPFIKILDKQYLKDEKSNVAEEDDDISFDDLVL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=464, Percent_Identity=31.6810344827586, Blast_Score=212, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 48344; Mature: 48344

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLVANFPIKGWNEFVGQIF
CCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIASAAVAIVAFFIITPFVIPY
CCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHEECC
TPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAAVVKKGWTLKMPDGVPPTVSK
CCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHH
SFAALIPSAIVMVVFFLVKIAFEATPYGNVHEFIFNFLQIPLLKLGNTLSATAIAYVFLH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGTKLPNIITAQFQDMFATFGGAGSTL
HHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHH
SLIIAMLLICKSKRIKSIGKLSILPGIFGINEPLIFGLPIMLNPLLLIPFALVPTVNIII
HHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHH
AYFCMSTGLVPLTNGVQLPWTTPIIFSGFLTTGWQGAVLQLVLLILGIFMYIPFIKILDK
HHHHHHCCCEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QYLKDEKSNVAEEDDDISFDDLVL
HHHHHHHHCCCCCCCCCCHHHHCC
>Mature Secondary Structure
MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLVANFPIKGWNEFVGQIF
CCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIASAAVAIVAFFIITPFVIPY
CCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHEECC
TPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAAVVKKGWTLKMPDGVPPTVSK
CCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHH
SFAALIPSAIVMVVFFLVKIAFEATPYGNVHEFIFNFLQIPLLKLGNTLSATAIAYVFLH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGTKLPNIITAQFQDMFATFGGAGSTL
HHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHH
SLIIAMLLICKSKRIKSIGKLSILPGIFGINEPLIFGLPIMLNPLLLIPFALVPTVNIII
HHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHH
AYFCMSTGLVPLTNGVQLPWTTPIIFSGFLTTGWQGAVLQLVLLILGIFMYIPFIKILDK
HHHHHHCCCEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QYLKDEKSNVAEEDDDISFDDLVL
HHHHHHHHCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]